[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"return-of-spontaneous-circulation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:return-of-spontaneous-circulation":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,69],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100651475","kinetics-and-prognostic-value-of-neurofilament-light-in-post-cardiac-arrest-a-prospective-multicenter-study-100651475",false,"NCT07760636","Kinetics and Prognostic Value of NeuroFilament Light in Post-cardiac Arrest: A Prospective Multicenter Study","CINEFIL","Inclusion Criteria:\n\n* Patients admitted to the ICU for cardiac arrest,\n* Patients who regained consciousness following in-hospital or out-of-hospital cardiac arrest,\n* Patients in a coma upon arrival in the ICU, defined by a Glasgow Coma Scale (GCS) score \\\u003C8,\n* Patients included in the AfterROSC2 cohort,\n\nExclusion Criteria:\n\n* Terminally ill patients (death expected within 3 hours of admission to the ICU),\n* Minors,\n* Patients under legal guardianship,\n* Pregnant women,\n* Patients not enrolled in a social security program,\n* Prior inclusion in the CINEFIL study,\n* Restriction of active therapies prior to the first NFL biomarker assay,\n* Objection by a family member or trusted person, if present","ALL","18 Years",{"count":19,"type":20},270,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to assess the prognostic value of absolute value and kinetic of neurofilament light chain (NFL) collected at different time points (at admission, 12h, 24h, 48h, 72h, 96h, and day 7 after ICU admission) in predicting poor and good neurological outcome in comatose patients after cardiac arrest.",[24,25,26,27],"Cardiac Arrest (CA)","Intensive Care Unit (ICU) Admission","Return of Spontaneous Circulation","Comatose",[29,30,31,32,33],"Cardiac arrest","Coma","Neuroprognostication","Biomarkers","Neurofilament light chain","NOT_YET_RECRUITING","2026-08-10",{"date":37,"type":38},"2026-08-12","ACTUAL",{"date":40,"type":20},"2026-09",{"date":42,"type":20},"2028-06",{"name":44,"class":45},"Assistance Publique - Hôpitaux de Paris","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":46},"100649042","pulse-detection-in-cardiac-arrest-patients-using-a-doppler-ultrasound-patch-on-the-carotid-artery-100649042","NCT07729228","Pulse Detection in Cardiac Arrest Patients Using a Doppler Ultrasound Patch on the Carotid Artery","Inclusion Criteria:\n\n* Any adult patient aged \\> 18 to 99 years old\n* Intact skin on their neck\n* In cardiac arrest with an arterial line placed during the resuscitation event as part of the standard of care.\n\nExclusion Criteria:\n\n* Patients in cardiac arrest with a Do Not Resuscitate\u002FDo Not Intubate (DNR\u002FDNI) order.\n* Patients without an arterial line in place as part of the standard of care.\n* \\*Pregnant women\n* \\*Prisoners\n\n  * Any data from these two populations (pregnant\u002Fprisoner) will not be downloaded at all if it is discovered post-resuscitation event that the patient is pregnant and\u002For a prisoner.","99 Years",{"count":55,"type":20},20,"The purpose of this study is to find out if a Doppler ultrasound patch placed on the neck can accurately and quickly detect when a cardiac arrest patient's heart starts beating again (return of spontaneous circulation, or ROSC) during resuscitation in the emergency department. The study compares the ultrasound readings to data from an arterial line, which is considered the most reliable way to check for a pulse. The main question the study is trying to answer is whether using Doppler ultrasound is better than the traditional method of feeling for a pulse, which can be unreliable, especially in stressful situations. Secondarily, this study aims to assess blood flow through the carotid artery from chest compressions during resuscitative events to determine overall effectiveness. This research hopes to show that Doppler ultrasound can help medical teams recognize when a patient's heart has restarted more accurately and quickly, leading to better care during cardiac arrest.",[24,26,58],"CPR Quality Assessment","2026-07-24",{"date":61,"type":38},"2026-07-27",{"date":63,"type":20},"2026-08-15",{"date":65,"type":20},"2027-08-15",{"name":67,"class":68},"Heartstream US LLC","INDUSTRY",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":76,"enrollmentInfo":77,"targetDuration":4,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":4,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":46},"100551086","phase-1-post-ca-neuroprotection-with-magnesium-100551086","NCT06455514","Post-CA Neuroprotection With Magnesium","Neuroprotection Following Cardiac Arrest: A Randomized Control Trial of Magnesium","Inclusion Criteria:\n\n* Documented post-cardiac arrest patient with Return of Spontaneous Circulation (ROSC) achieved \\\u003C2 hours prior to recruitment\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years or \\> 85 years\n* Traumatic cardiac arrests\n* Unsustained ROSC (\\\u003C20 minutes)\n* Patient who is responsive\u002Fable to follow motor commands within 1 hour of achieving ROSC\n* Plan for withdrawal of life support within 72 hours of ROSC\n* Known pregnant women at the time of the cardiac arrest\n* Known prisoners at the time of the cardiac arrest\n* Subjects who have a medical o social condition that would make them inappropriate for the study based on the PI's or clinical team judgement.","85 Years",{"count":78,"type":20},178,"INTERVENTIONAL",[81],"PHASE1","The purpose of this pilot interventional study is to collect preliminary data on administering magnesium sulfate as a neuroprotective medication in patients who achieved Return of Spontaneous Circulation (ROSC) following Cardiac Arrest (CA). The primary aims are to assess the feasibility and safety of administering magnesium and measure serum markers of neuronal injury at prespecified time points in the post-cardiac arrest period. Because this is a pilot study with a limited sample size, the primary objective is to evaluate the precision and stability of the collected measures to inform the design and formal analysis in a larger trial.",[84,26],"Cardiac Arrest","RECRUITING","2026-04-01",{"date":88,"type":38},"2026-04-07",{"date":90,"type":38},"2025-03-25",{"date":92,"type":20},"2026-06-30",{"name":94,"class":45},"NYU Langone Health"]