[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"rotator-cuff-tears-rcts\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:rotator-cuff-tears-rcts":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100652948","smallest-worthwhile-effect-of-rotator-cuff-repair-and-supervised-exercise-100652948",false,"NCT07779876","Smallest Worthwhile Effect of Rotator Cuff Repair and Supervised Exercise","Determining the Smallest Worthwhile Effect of Rotator Cuff Repair and Supervised Exercise: A Benefit-Harm Trade-off Study","Inclusion Criteria:\n\n* Over 18 years of age\n* Diagnosed with rotator cuff tear by a specialist doctor\n* Having pain and functional limitation for at least 4 weeks\n* Having a pain level of 3 or higher on the Numeric Pain Scale (NPS)\n\nExclusion Criteria:\n\n* Presence of another pathology in the affected shoulder region\n* Presence of radiculopathy originating from the cervical region or internal organs\n* Presence of neurological, rheumatological, or oncological disease\n* Insufficient cooperation of the patient with the procedures to be performed within the scope of the study","ALL","18 Years",{"count":19,"type":20},104,"ESTIMATED","OBSERVATIONAL","The goals of this observational study are (1) to determine the smallest worthwhile effect of rotator cuff repair surgery compared to exercise therapy in rotator cuff patients; (2) to determine the smallest worthwhile effect of supervised exercise therapy compared to unsupervised exercise therapy in rotator cuff patients. Another objective of the study is to identify the demographic and clinical factors affecting the smallest worthwhile effect.\n\nThe main questions it aims to answer are:\n\n1. What is the smallest worthwhile effect of rotator cuff repair surgery compared to exercise therapy?\n2. What is the smallest worthwhile effect of supervised exercise therapy compared to unsupervised exercise therapy?\n3. Do demographic and clinical factors influence the smallest worthwhile effect? Participants will be asked to provide demographic and clinical data and to answer questions on a survey.",[24],"Rotator Cuff Tears (RCTs)",[26,27,28,29,30],"rotator cuff tear","rotator cuff repair","exercise","smallest worthwhile effect","benefit-harm trade-off method","NOT_YET_RECRUITING","2026-08-18",{"date":34,"type":35},"2026-08-21","ACTUAL",{"date":37,"type":20},"2026-10",{"date":39,"type":20},"2027-12",{"name":41,"class":42},"Kırklareli University","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":4},"100641423","platelet-rich-plasma-for-partial-rotator-cuff-tears-100641423","NCT07659600","Platelet-Rich Plasma for Partial Rotator Cuff Tears","Performance of Autologous Platelet-rich Plasma Injection for Tendon Regeneration in Partial Supraspinatus Tears","OPTIMISE","Inclusion Criteria:\n\n* Eligible patients are at least 18 years old, and have clinical (VAS pain score ≥4, loss of \\>25% in ROM, positive in at least one clinical test such as Jobe, Neer, Drop arm, Hawins-Kennedy, Patte) and imaging findings compatible with partial supraspinatus tear, within 3 months of diagnosis.\n* Patients may have undergone conservative treatments, including lifestyle modification, oral analgesics, or physical therapy, with the exception of shoulder injections.\n* Must be willing to provide consent.\n\nExclusion Criteria:\n\n* Patients less than 18 years old\n* Patients with other or concomitant rotator cuff or shoulder muscle\u002Ftendon tear(s), complete tears, SLAP tears ≥ grade 2\n* Patients with auto-immune based joint diseases, osteoarthritis (KL grade ≥ 2), adhesive capsulitis, infection, nerve-related conditions, immunocompromised conditions, malignancy, coagulopathy\n* Patients on antiplatelet, anticoagulant, antitumor or immunosuppressive drugs\n* Uncontrolled diabetes, other systemic disorders (hepatitis, rheumatoid arthritis)\n* Pregnancy\n* Shoulder instability\n* Previous shoulder injection or surgery\n* Unwillingness to provide informed consent",{"count":52,"type":20},100,"INTERVENTIONAL",[55],"NA","The goal of this clinical trial is to learn whether platelet-rich plasma (PRP) injection, made from a participant's own blood, can help heal the tendon and improve shoulder symptoms in people with partial tears of the supraspinatus tendon.\n\nThe main questions it aims to answer are:\n\n* Does PRP help the tendon heal?\n* Does PRP improve pain, shoulder movement, daily function, and shoulder magnetic resonance imaging (MRI) findings?\n\nResearchers will compare PRP plus standard of care (physical therapy) to standard of care alone to see if PRP leads to better healing and better clinical results. Researchers will also study if differences in specific biomolecules in PRP are associated with differences in treatment response.\n\nParticipants will:\n\n* receive standard of care treatment, with or without PRP injection depending on the study group\n* have blood collected for PRP preparation\n* have their pain, shoulder movement, and shoulder function assessed\n* undergo shoulder MRI scans\n* be followed over time to measure healing and symptom improvement",[58,24,59],"Partial Supraspinatus Tear","Rotator Cuff Injury",[61,62,63,64,65,66],"Platelet-Rich Plasma","Partial Supraspinatus Tears","Rotator Cuff Tears","Autologous PRP","PRP","Shoulder pain","2026-06-15",{"date":69,"type":35},"2026-06-22",{"date":71,"type":20},"2026-06-01",{"date":73,"type":20},"2029-12-01",{"name":75,"class":42},"Universidade Nova de Lisboa"]