[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"serrated-polyps\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:serrated-polyps":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":5},"100654176","evaluation-of-versatile-intelligent-staining-technology-vist-and-spectral-flexible-imaging-sfi-for-detection-and-optical-characterization-of-colorectal-lesions-a-prospective-randomized-controlled-study-100654176",false,"NCT07797361","Evaluation of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for Detection and Optical Characterization of Colorectal Lesions: A Prospective Randomized Controlled Study","Evaluation of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for Detection and Optical Characterization of Colorectal Lesions: A Prospective Randomized Controlled Study (INSIGHT Study)","INSIGHT","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Undergoing screening or surveillance colonoscopy\n* Adequate bowel preparation (Boston Bowel Preparation Scale ≥6, with ≥2 per segment)\n* Ability to understand and sign informed consent\n\nExclusion Criteria:\n\n* History of inflammatory bowel disease (Crohn's disease or ulcerative colitis)\n* Prior colorectal resection\n* Colorectal stenosis preventing scope progression\n* Pregnancy or breastfeeding\n* Inadequate bowel preparation\n* Clinical contraindication to colonoscopy","ALL","18 Years",{"count":20,"type":21},990,"ESTIMATED","INTERVENTIONAL",[24],"NA","This prospective randomized controlled study aims to evaluate the diagnostic accuracy of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for detection and optical characterization of colorectal lesions during colonoscopy. The performance of VIST and SFI will be compared with high-definition white light endoscopy (WLE), using histopathology as the reference standard and established endoscopic classifications (Paris, Kudo, and JNET). The study will also assess adenoma detection rate, serrated lesion detection, inter- and intraobserver agreement, and procedure-related metrics.",[27,28,29,30,31],"Colorectal Neoplasms","Colonic Polyps","Adenoma","Serrated Polyps","Colorectal Cancer Screening",[33,34,35,36,37,38,39,40,41,42],"Colonoscopy","Adenoma Detection Rate","Optical Diagnosis","Image-Enhanced Endoscopy","Electronic Chromoendoscopy","Versatile Intelligent Staining Technology (VIST)","Spectral Flexible Imaging (SFI)","White Light Endoscopy","JNET Classification","Kudo Pit Pattern","NOT_YET_RECRUITING","2026-08-26",{"date":46,"type":47},"2026-09-01","ACTUAL",{"date":49,"type":21},"2026-10-01",{"date":51,"type":21},"2028-08-31",{"name":53,"class":54},"Alexandre Vontobel Padoin","OTHER"]