[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"spasticdystonic-quadriplegia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:spasticdystonic-quadriplegia":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100655764","outcomes-of-neurosurgical-tone-management-100655764",false,"NCT07817745","Outcomes of Neurosurgical Tone Management","Inclusion Criteria:\n\n* Any patients undergoing intrathecal baclofen pump insertion or combined dorsal ventral rhizotomy at Boston Children's Hospital.\n* Must be at least 6 years of age at time of enrollment\n\nExclusion Criteria:\n\n\\-","ALL","6 Years","25 Years",{"count":19,"type":20},100,"ESTIMATED","OBSERVATIONAL","Patients with spastic\u002Fdystonic quadriplegia (GMFCS IV\u002FV) are often severely disabled by their tone, and require surgical tone management to improve quality of life, allow for better function, improve comfort, and range of motion. This has historically been limited to Intrathecal Baclofen (ITB) pumps, which are effective for up to 85% of patients but carry significant morbidity \u002F complications and are not appropriate for many patients. More recently, combined dorsal\u002Fventral rhizotomy (CR) has emerged as an alternative means for tone control, a one-time surgery with no required hardware implantation. However, more information is needed regarding long-term outcomes of this procedure in addition to comparative outcomes of ITB. This information will lead to improved patient selection, counseling, and care. This is a prospectively enrolled, single-center study, involving survey administration and clinical observation of outcomes pre- and post-surgery.",[24,25],"Spastic\u002FDystonic Quadriplegia","Cerebral Palsy (CP)",[27,28,29,30,31,32,33,34],"CP","Cerebral Palsy","Tone Management","Dystonic","Spastic","Spasticity","Intrathecal Baclofen Pump","Combined Dorsal\u002FVentral Rhizotomy","RECRUITING","2026-09-08",{"date":38,"type":39},"2026-09-14","ACTUAL",{"date":41,"type":39},"2024-06-26",{"date":43,"type":20},"2031-01-01",{"name":45,"class":46},"Boston Children's Hospital","OTHER"]