[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"surgical\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:surgical":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,52,86],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":31,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100646440","deformable-tissue-modelling-and-augmented-reality-based-guidance-for-head-and-neck-tumor-re-resection-task-100646440",false,"NCT07686211","Deformable Tissue Modelling and Augmented Reality Based Guidance for Head and Neck Tumor Re-Resection Task","SPeAR","Inclusion Criteria:\n\n1. Post-graduate year 1, 2, 3, 4 and 5 (PGY2-5) resident physicians. (no age limit)\n2. Surgical fellows.\n3. Attending physicians.\n4. Prior cadaver lab or surgical experience.\n5. Any surgeon, regardless of training and experience, who has been involved in the surgeon-pathologist interaction during surgical resection for frozen section and margin clearance assessment.\n\nExclusion Criteria:\n\n1\\. Non-physician surgery providers.","ALL",{"count":18,"type":19},30,"ESTIMATED","INTERVENTIONAL",[22],"EARLY_PHASE1","Head and neck cancers have one of the highest recurrence rates among solid malignancies, and recurrence is strongly correlated with overall survival. Reducing recurrence rates depends, in part, on the surgeon's ability to accurately re-resect areas of positive or close margins during surgery. Currently, margin status is communicated primarily through verbal descriptions between the surgeon and pathologist, which can be imprecise. This challenge is further compounded by the deformable nature of soft tissues, as once the specimen is resected, the shape and size of the specimen change, making it difficult to accurately map the specimen's margins back onto the surgical site.\n\nEmerging technologies -such as augmented reality (AR), 3D scanning, and advanced soft tissue modeling- offer promising solutions for improving surgical navigation and precision. Building on these advances, an AR-based surgical navigation system was developed specifically for head and neck tumor resections. The system uses a 3D scanner to generate virtual models of both the resected specimen and the patient's surgical site, as demonstrated in prior work. A soft tissue modeling algorithm is then applied to account for specimen shrinkage and deformation, enabling accurate tracking of positive tumor margins. This guidance information is visualized through an AR headset, which overlays the margin data directly onto the patient's surgical site, providing surgeons with real-time visual guidance during re-resection.\n\nIn this study, the goal is to evaluate the benefits and usability of this novel navigation software, compared to the standard of care. By assessing surgeon performance and user experience in cadaveric tasks with and without the AR system to identify strengths, limitations, and opportunities for refinement of the system, ultimately advancing surgical precision and improving patient outcomes by reducing recurrence rates.",[25,26,27,28,29,30],"Physician","Surgeon","Resident Doctor","Resident Surgeon","Surgical","Fellow",[32,33,34,35,36,37,38],"physician","surgeon","resident doctor","doctor","surgical","fellow","resident surgeon","RECRUITING","2026-08-05",{"date":42,"type":43},"2026-08-10","ACTUAL",{"date":45,"type":43},"2026-02-18",{"date":47,"type":19},"2029-06",{"name":49,"class":50},"Vanderbilt University Medical Center","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":16,"minAge":59,"maxAge":4,"enrollmentInfo":60,"targetDuration":4,"studyType":20,"phases":62,"briefSummary":64,"conditions":65,"keywords":70,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":4},"100618913","implementation-of-clinical-nutrition-practice-guidelines-in-surgical-icus-100618913","NCT07337798","Implementation of Clinical Nutrition Practice Guidelines in Surgical ICUs","Effects of Implementing Evidence-Based Clinical Nutrition Practice Guidelines in Surgical Intensive Care Units: A Cohort Study","Inclusion Criteria:\n\nFor ICU healthcare professionals:\n\nEmployed at one of the participating study sites (tertiary general hospitals)\n\nHolds a valid Registered Nurse license issued in the People's Republic of China\n\nCurrently working in frontline clinical nursing care in a surgical intensive care unit (ICU) during the study period\n\nAt least 1 year of clinical working experience\n\nAble to understand the study objectives and procedures\n\nWilling to participate and able to provide written informed consent\n\nFor surgical critically ill patients (outcome assessment population):\n\nAged 18 years or older\n\nAdmitted to a surgical ICU due to surgical-related conditions, including trauma, infection, malignancy, or postoperative complications\n\nExpected length of stay in the surgical ICU of at least 48 hours\n\nNo restriction on sex\n\nPatient or legally authorized representative able to provide written informed consent\n\nExclusion Criteria:\n\nFor ICU healthcare professionals:\n\nCurrently pregnant, breastfeeding, or planning pregnancy during the study period\n\nTemporarily assigned, rotating, externally dispatched, on long-term training, or on leave during the study period, making continuous participation impossible\n\nParticipation in other interventional studies that may interfere with the implementation of this study\n\nDetermined by the research team to have cognitive, communication, or other conditions that would make participation inappropriate\n\nFor surgical critically ill patients:\n\nDiagnosed with brain death or awaiting organ donation\n\nPregnant or breastfeeding women\n\nConcurrent participation in other nutrition-related clinical trials","18 Years",{"count":61,"type":19},200,[63],"NA","The goal of this interventional clinical trial is to evaluate whether the implementation of an evidence-based, context-adapted clinical nutrition practice guideline can improve clinical nutrition management in surgical intensive care units (ICUs) in China. The guideline is selected based on the best available evidence from existing surgical and critical care nutrition guidelines, adapted to the Chinese healthcare context, and implemented using an i-PARIHS-guided translation strategy. The trial involves ICU healthcare professionals working in surgical ICUs of tertiary general hospitals, while assessing nutrition-related clinical outcomes among surgical critically ill patients.\n\nThe main questions it aims to answer are:\n\nDoes guideline implementation improve ICU healthcare professionals' adherence to recommended clinical nutrition practice guidelines?\n\nDoes the implementation of the clinical nutrition practice guideline improve the proportion of surgical critically ill patients who achieve recommended energy and protein intake targets during ICU stay?\n\nResearchers will compare outcomes before and after guideline implementation to determine whether the i-PARIHS-guided guideline translation improves nutrition management processes, healthcare professional performance, and patient-related clinical outcomes.\n\nParticipants will:\n\nComplete baseline and post-implementation assessments related to clinical nutrition knowledge, attitudes, and practices.\n\nParticipate in guideline-based education, training, and implementation activities guided by the i-PARIHS framework.\n\nApply the adapted clinical nutrition practice guideline during routine clinical care in surgical ICUs.\n\nBe evaluated through on-site audits, questionnaires, and clinical data collection during the implementation process.",[66,29,67,68,69],"ICU Patients","Nutrition Intervention","Enteral Nutrition","Enteral Nutrition Intolerance",[71,72,73,74,75],"Clinical Nutrition","Surgical Intensive Care Units","i-PARIHS Framework","Implementation Science","Clinical practice guideline","NOT_YET_RECRUITING","2026-01-11",{"date":79,"type":43},"2026-01-13",{"date":81,"type":19},"2025-12-20",{"date":83,"type":19},"2026-12-31",{"name":85,"class":50},"Xuanwu Hospital, Beijing",{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":93,"minAge":59,"maxAge":4,"enrollmentInfo":94,"targetDuration":96,"studyType":97,"phases":4,"briefSummary":98,"conditions":99,"keywords":103,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":117},"100543512","national-registry-of-surgical-treatment-and-percutaneous-cryoablation-of-parietal-endometriosis-100543512","NCT06356831","National Registry of Surgical Treatment and Percutaneous Cryoablation of Parietal Endometriosis","Endomercyo","Inclusion Criteria:\n\n* Presence of parietal endometriosis: with suggestive clinical and imaging criteria (MRI and ultrasound)\n* Symptomatic parietal endometriosis (VAS \\> 3 OR bothersome bleeding OR reported impact on quality of life)\n\nExclusion Criteria:\n\n* Endometriosis not affecting the anterior wall of the abdomen (as deep pelvic muscle: ilio-psoas, obturators, perineal, ischio-anal fossa)\n* Minor patient (\\\u003C 18 years)\n* Pregnant patient at any trimester\n* Patient with hemostasis disorders (constitutional or acquired)\n* Patient with systemic infection or localized scar infection upon inclusion.\n* Patient with contraindications to MRI\n* Female patient with a planned medical or surgical procedure for the duration of the study that may interfere with the proper conduct of the study.\n* Patient unable to understand the information provided\n* Patient who is not affiliated to the social security system\n* Patient under curatorship or tutorship\n* Patient with a nodule of primary or secondary malignant tumor origin","FEMALE",{"count":95,"type":19},300,"3 Years","OBSERVATIONAL","National multicentric registry of a cohort of patient with suffering parietal endometriosis, carried out by a multidisciplinary radiosurgery team",[100,101,29,102],"Endometriosis","Cryotherapy Effect","Radiology",[104,105,106,107],"endometriosis","Cryo ablation","Surgical operation","radiology","2025-11-26",{"date":110,"type":43},"2025-11-28",{"date":112,"type":43},"2024-06-15",{"date":114,"type":19},"2028-01-31",{"name":116,"class":50},"Centre Hospitalier Intercommunal Creteil",18]