[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"swallowing-function\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:swallowing-function":33},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,53,85,113,145],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":35,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100647853","effects-of-a-perma-h-model-mobile-based-rehabilitation-support-program-on-hope-self-efficacy-perceived-social-support-and-rehabilitation-outcomes-in-post--tracheostomy-oral-cancer-patients-100647853",false,"NCT07714967","Effects of a Perma-h Model Mobile-based Rehabilitation Support Program on Hope, Self-efficacy, Perceived Social Support and Rehabilitation Outcomes in Post- Tracheostomy Oral Cancer Patients","Inclusion Criteria:\n\n* Aged ≥18 years\n* Pathologically diagnosed with oral squamous cell carcinoma and undergoing, or scheduled to undergo, tracheostomy followed by decannulation\n* Fully conscious, with a Glasgow Coma Scale score of 15, and able to successfully complete the Three-Step Command Test, indicating intact comprehension ability\n* Able to communicate effectively through verbal speech or alternative methods, including writing, gestures, electronic device input, or voice-assisted tools\n* Able to use WeChat independently or after brief guidance, without communication barriers\n* Has at least one regular family caregiver; both the patient and caregiver fully understand the study content and voluntarily provide written informed consent\n* Free from severe cardiovascular, cerebrovascular, hepatic, renal, or pulmonary disease\n\nExclusion Criteria:\n\n* Presence of other serious malignancies or extensive tumor metastasis\n* Previous or current diagnosis of severe mental illness, such as schizophrenia or severe bipolar disorder\n* Significant cognitive impairment, severe depressive symptoms, or suicide risk that precludes effective participation in psychological interventions\n* Inability to complete assessments or interventions due to severe hearing, visual, or language impairments\n* Inability to communicate effectively through any available alternative means\n* Lack of access to a smartphone and absence of a designated caregiver\n* Explicit unwillingness or inability to use a mobile-based rehabilitation support program\n* Unexpected inability to complete the full intervention cycle, including planned hospital transfer or prolonged loss to follow-up\n* Concurrent participation in other clinical studies primarily focused on psychological or mobile health interventions that could confound study outcomes","ALL","18 Years",{"count":18,"type":19},100,"ESTIMATED","INTERVENTIONAL",[22],"NA","The goal of this study (exploratory sequential design; mixed-methods study) is to evaluate whether a PERMA-H model mobile-based rehabilitation support program delivered to post-tracheostomy oral cancer patients can improve psychological and rehabilitation outcomes, compared with a control group receiving usual care\u002Fstandard support. The study will focus on post-tracheostomy oral squamous cell carcinoma (OSCC) patients (aged ≥18 years) who are undergoing or scheduled to undergo tracheostomy followed by decannulation, and who have adequate communication ability and caregiver support.\n\nThe main questions it aims to answer are:\n\nDoes the PERMA-H model mobile-based rehabilitation support program improve patients' hope? (primary hypothesis\u002Foutcome measure 1) Does the PERMA-H model mobile-based rehabilitation support program improve patients' self-efficacy, perceived social support, and rehabilitation outcomes? (primary hypothesis\u002Foutcome measure 2) If there is a comparison group, researchers will compare the PERMA-H model mobile-based rehabilitation support program (intervention group) to a control group receiving standard\u002Fusual care (control group) to determine differences in outcomes between groups.\n\nParticipants will be asked to complete the main study tasks, including:\n\nparticipating in qualitative interviews to explore their digital needs, expectations, and experiences regarding psychosocial care (Phase I); using the WeChat mini-program platform that incorporates a PERMA-H evidence-based module set and a chatbot (Decannulationbot \u002F Digital rehabilitation Assistant, DDA) as part of the rehabilitation support program; completing validated assessments at study endpoints to measure hope (Herth Hope Index), self-efficacy (General Self-Efficacy Scale), and perceived social support (Perceived Social Support Scale), as well as rehabilitation-related outcomes (including rehabilitation willingness\u002Fparticipation and functional measures such as swallowing function and speech intelligibility as rated by speech-language pathologists).\n\nExpected outcomes include: comprehensive qualitative findings to inform the content and delivery of digital psychosocial support; a functional mobile intervention platform with evidence-based modules validated through expert appraisal and pilot testing; and statistically significant improvements in hope, self-efficacy, perceived social support, and rehabilitation outcomes in the intervention group compared with the control group.",[25,26,27,28,29,30,31,32,33,34],"Tracheostomized Patients","Decanulation","Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer","Rehabilitation Outcome","Mental Health","Hope","Self Efficacy","Perceived Social Support","Swallowing Function","Speech Intelligibility",[36,37,38,39],"PERMA-H","chatbot","Digital Rehabilitation Support","MODEL MOBILE","NOT_YET_RECRUITING","2026-07-15",{"date":43,"type":44},"2026-07-20","ACTUAL",{"date":46,"type":19},"2026-08-01",{"date":48,"type":19},"2027-02-01",{"name":50,"class":51},"Hainan Medical College","OTHER",2,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":62,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":84},"100639039","ddk-acoustic-analysis-and-swallowing-indicators-100639039","NCT07626749","DDK Acoustic Analysis and Swallowing Indicators","Acoustic Analysis of Performance in Diadochokinetic (DDK) Tasks and Swallowing Function Indicators Among Adults Across Different Age Groups","AAP-DDK","Inclusion Criteria:\n\n* 1.Community-dwelling adults aged 18 years or older, with no upper age limit.\n* 2.Ability to communicate in Mandarin or Taiwanese and understand the study procedures.\n* 3.Willingness to provide written informed consent.\n* 4 .Ability to complete the DDK tasks and RSST.\n\nExclusion Criteria:\n\n* 1.Presence of acute respiratory infection, upper respiratory inflammation, or other acute conditions that may significantly affect speech or swallowing.\n* 2.Impaired consciousness, significant cognitive deficits, or inability to understand the study procedures.\n* 3.Recent surgery or radiotherapy involving the oral cavity or pharynx that affects speech or swallowing.\n* 4.Severe hearing impairment that prevents understanding of instructions.\n* 5.Any other condition deemed unsuitable for participation by the investigators.",true,{"count":63,"type":19},720,"OBSERVATIONAL","This study examines whether simple speech tasks and a swallowing screening test can help identify swallowing risk in adults of different ages. Participants will complete basic questions, a swallowing self-assessment, a saliva swallowing test, and short voice recordings of rapid syllables. The study is non-invasive, takes about 75 minutes, and may help develop an easy, low-cost screening tool for early swallowing problems.",[33,67,68],"Swallowing Risk","Dysphagia",[68,33,70,71,72,73,74],"diadochokinetic","Acoustic Analysis","Repetitive Saliva Swallowing Test","EAT-10","Older Adults","2026-05-29",{"date":77,"type":44},"2026-06-04",{"date":79,"type":19},"2026-06-15",{"date":81,"type":19},"2030-04-09",{"name":83,"class":51},"Kaohsiung Medical University",1,{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":93,"targetDuration":95,"studyType":64,"phases":4,"briefSummary":96,"conditions":97,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":4},"100617607","quality-of-life-and-functional-outcomes-in-laryngeal-cancer-patients-100617607","NCT07320820","Quality of Life and Functional Outcomes in Laryngeal Cancer Patients","Assessment of Quality of Life, Patient Satisfaction, Swallowing Function, Voice Outcomes, Pain, and Anxiety-Depression at Baseline and at 3-, 6-, and 12-Month Follow-Up in Patients Diagnosed With Laryngeal Squamous Cell Carcinoma: A Prospective Questionnaire-Based Study","QoL in LSSC","Inclusion Criteria:\n\n* Age ≥ 18 years at the time of enrollment.\n* Histopathologically confirmed diagnosis of laryngeal squamous cell carcinoma.\n* Planned to undergo surgical treatment or radiotherapy\u002Fchemoradiotherapy as part of standard oncological care.\n* Willing and able to participate in the study and to provide written informed consent.\n* No history of psychiatric or neurological disorders that could impair comprehension, questionnaire completion, or study participation.\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years.\n* Presence of comorbid conditions that may independently affect swallowing or voice functions.\n* Patients who withdraw consent or request to discontinue participation during or after the treatment period.\n* History of psychiatric disorders or use of psychiatric medications that may interfere with study participation or completion of patient-reported outcome measures.",{"count":94,"type":19},120,"12 Months","Laryngeal squamous cell carcinomas are head and neck malignancies that directly affect both swallowing and voice functions and are associated with a significant deterioration in patients' quality of life throughout the treatment process.\n\nThe aim of this study is to evaluate quality of life, voice and swallowing functions, pain, anxiety-depression levels, and patient satisfaction at the pre-treatment period and at the 3rd, 6th, and 12th months post-treatment in patients with laryngeal malignancies, using validated questionnaires, in order to:\n\nElucidate the course of functional recovery following treatment,\n\nIndividualize rehabilitation and follow-up strategies, and\n\nExamine the relationship between functional outcomes and oncological survival.",[98,99,100,101,33,102,103],"Laryngeal Carcinoma","Quality of Life (QOL)","Patient Satisfaction","Voice Quality","Pain Management","Anxiety Depression","2026-04-21",{"date":106,"type":44},"2026-04-22",{"date":108,"type":19},"2026-04-02",{"date":110,"type":19},"2027-12-31",{"name":112,"class":51},"Saglik Bilimleri Universitesi",{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":117,"acronym":4,"eligibilityCriteria":118,"healthyVolunteers":61,"sex":15,"minAge":119,"maxAge":120,"enrollmentInfo":121,"targetDuration":123,"studyType":64,"phases":4,"briefSummary":124,"conditions":125,"keywords":128,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":143,"locationsCount":84},"100627949","surface-electromyographic-analysis-of-normal-swallowing-in-children-an-exploratory-study-100627949","NCT07455279","Surface Electromyographic Analysis of Normal Swallowing in Children: An Exploratory Study","Inclusion Criteria:\n\n* Children aged 2 to under 10 years\n* Children without a diagnosis of dysphagia\n* Children without congenital brain lesions or respiratory conditions (e.g., bronchopulmonary dysplasia \\[BPD\\], respiratory distress syndrome \\[RDS\\]) that may affect the swallowing process\n* Children whose legal guardians provide informed consent for participation\n* Participants who meet all of the above inclusion criteria\n\nExclusion Criteria:\n\n* Refusal to provide consent for participation in the study\n* Refusal to undergo the study procedures or assessments\n* Determined by the principal investigator to be unsuitable for participation -Meeting any of the above exclusion criteria -","2 Years","10 Years",{"count":122,"type":19},30,"1 Day","This exploratory clinical trial aims to investigate the mechanism of sequential muscle contractions during normal swallowing processes, including spoon, straw, and cup feeding, in children aged 2 to under 10 years without swallowing disorders. Surface electromyography (sEMG) will be used to evaluate activation patterns of the orbicularis oris, submental, and hyoid muscles during liquid, semi-solid, and solid intake.\n\nThe study seeks to characterize the timing, duration, amplitude, and coordination of swallowing-related muscle activity in typically developing children. Findings from this study are expected to provide foundational physiological data to inform the development of pediatric-specific neuromuscular electrical stimulation (NMES) protocols for dysphagia treatment.",[126,127,33],"Normal Pediatric Swallowing Physiology","Swallowing Muscle Activation Patterns in Children",[129,130,131,132,133,134,135],"Pediatric Swallowing","Swallowing Physiology","Surface Electromyography","Swallowing Muscle Activation","Normative Data","Deglutition","Developmental Physiology","2026-03-02",{"date":138,"type":44},"2026-03-06",{"date":140,"type":19},"2026-03-09",{"date":142,"type":19},"2028-01-31",{"name":144,"class":51},"Seoul National University Bundang Hospital",{"id":146,"slug":147,"hasResults":11,"nctId":148,"briefTitle":149,"officialTitle":150,"acronym":4,"eligibilityCriteria":151,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":152,"enrollmentInfo":153,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":155,"conditions":156,"keywords":157,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":4},"100573509","dysphagia-in-head-and-neck-cancer-with-radiation-100573509","NCT06747208","Dysphagia in Head and Neck Cancer With Radiation","The Impact of Swallowing and Nutrition in Head and Neck Cancer Patients Undergoing Chemo or Chemo-radiotherapy.","Inclusion Criteria:\n\n* Patients scheduled to undergo radiotherapy or concurrent chemoradiotherapy ;\n* Aged between 18 and 80 years;\n* Able to perform self-care independently (ECOG ≤ 2);\n* All patients provide written informed consent.\n\nExclusion Criteria:\n\n* Patients scheduled to undergo surgical treatment;\n* Patients with neuromuscular diseases, such as stroke or Parkinson's disease;\n* Patients with other diseases or complications, including heart disease classified as NYHA functional class ≥ 2 with thrombotic conditions, or lung disease classified as Hugh-Jones grade ≥ 4;\n* Patients with psychological disorders that may affect their ability to provide informed consent or comply with the study protocol;\n* Patients who do not consent to undergo high-resolution impedance manometry.","80 Years",{"count":154,"type":19},50,"This study focuses on swallowing dysfunction, a common issue affecting 60-75% of head and neck cancer patients due to tumor damage, treatment complications, and chemoradiotherapy side effects, which can lead to malnutrition and reduced quality of life. With limited research on the effects of radiation doses on swallowing muscles and nutrition, this study aims to evaluate these impacts in non-surgical patients undergoing radiotherapy, conducting assessments before treatment, three months after, and within one year post-treatment.",[33],[158,159,160],"dysphagia","head and neck cancer","radiation therapy","2024-12-18",{"date":163,"type":44},"2024-12-24",{"date":165,"type":19},"2025-01-01",{"date":167,"type":19},"2031-12-31",{"name":169,"class":51},"National Taiwan University Hospital"]