[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"this-study-aims-to-evaluate-the-safety-profile-and-tissue-changes-after-biostimulatory-treatments-to-the-face-in-healthy-volunteers\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:this-study-aims-to-evaluate-the-safety-profile-and-tissue-changes-after-biostimulatory-treatments-to-the-face-in-healthy-volunteers":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100592448","analysis-of-safety-and-tissue-interaction-of-injectable-biosmulators-100592448",false,"NCT06993558","Analysis of Safety and Tissue Interaction of Injectable Biosmulators","Analysis of Safety and Tissue Interaction of Injectable Biosmulators.","Biostimulation","-Inclusion Criteria:\n\nMen and women aged 30 years and older\n\nGood general health, no relevant pre-existing conditions\n\nPatients planning to undergo PLLA or CAHA treatment as part of routine care due to skin laxity or volume loss\n\nCognitive ability and willingness to provide informed consent\n\nWillingness and ability to attend follow-up visits\n\n-Exclusion Criteria:\n\nAge under 30 years\n\nPregnant or breastfeeding individuals\n\nSignificant open wounds or lesions in the treatment area\n\nMetallic implants in the treatment area\n\nPsychiatric disorders (psychosis, body dysmorphic disorders)\n\nMissing informed consent and\u002For data privacy declarations",true,"ALL","30 Years",{"count":21,"type":22},90,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to analyse tissue changes in the pre-auricular region after injectable (Poly-L-Lactic-Acid\u002FCalcium-Hydroxylapatit) biostimulatory interventions in healthy volunteers. The main questions it aims to answer are:\n\nHow is the Safety Profile of injectable Biostimulatory Treatments? How are the Tissue Interactions after injectable Biostiomulatory Treatments?\n\nParticipants will:\n\n* Recieve one of 2 possible biostumulatory treatments (PLLA\u002FCAHA\u002F\n* Attend 4 follow-up appointments after treatment for checkups, surveillance and examinations.",[28],"This Study Aims to Evaluate the Safety Profile and Tissue Changes After Biostimulatory Treatments to the Face in Healthy Volunteers",[30,15,31,32],"Ultrasound","Poly-L-Lactic-Acid","Calcium-Hydroxylapatit","RECRUITING","2026-07-13",{"date":36,"type":37},"2026-07-15","ACTUAL",{"date":39,"type":37},"2025-07-31",{"date":41,"type":22},"2027-09-15",{"name":43,"class":44},"Universitätsklinikum Hamburg-Eppendorf","OTHER"]