[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tiny-isothermal-nucleic-acid-amplification-system\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tiny-isothermal-nucleic-acid-amplification-system":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":31,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100653938","new-approaches-for-the-diagnosis-of-lymphoma-and-multicentric-castleman-disease-100653938",false,"NCT07793006","New Approaches for the Diagnosis of Lymphoma and Multicentric Castleman Disease","Inclusion Criteria:\n\n* Age ≥1 year old and body weight of ≥ 10 kg.\n* HIV-infected.\n* Unexplained lymphadenopathy with at least one lymph node ≥2 cm that is amenable to biopsy.\n* Willing and able to give informed consent if the subject is 18 years of age or older, adolescent assent and legal guardian consent for subjects 15-17 years of age, pediatric assent and legal guardian consent for subjects 7-14 years of age, or legal guardian consent for pediatric subjects less than 7 years of age.\n\nExclusion Criteria:\n\n* Cannot or is not willing to follow study procedures.\n* Subjects with a previous history of cancer in the last five years with the exception of subjects with Kaposi sarcoma (i.e. history of Kaposi sarcoma is allowed in the study).","ALL","1 Year",{"count":18,"type":19},500,"ESTIMATED","INTERVENTIONAL",[22],"NA","Persons living with HIV (PLWH) in sub-Saharan Africa (SSA), lymphadenopathy often portends one of a number of life-threatening diseases including tuberculosis, lymphoma, and multicentric Castleman disease (MCD). Overcoming these delays and missed diagnoses requires new approaches to identify lymphoma and MCD.",[25,26,27,28,29,30],"HIV","Kaposi Sarcoma Herpesvirus -Associated Multicentric Castleman Disease","Hodgkin Lymphoma","Non-Hodgkin Lymphoma","Tiny Isothermal Nucleic Acid Amplification System","Lymphadenopathy",[32],"Sub-Saharan Africa","RECRUITING","2026-08-25",{"date":36,"type":37},"2026-08-28","ACTUAL",{"date":39,"type":37},"2025-03-17",{"date":41,"type":19},"2028-12",{"name":43,"class":44},"Indiana University","OTHER"]