[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tooth-impacted\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tooth-impacted":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,43,77,113],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100652952","thbccgf-for-alveolar-bone-regeneration-a-real-world-study-100652952",false,"NCT07779421","THBC\u002FCGF for Alveolar Bone Regeneration: A Real-World Study","A Real-World Study on Temperature-Sensitive Hydroxybutyl Chitosan-Loaded Concentrated Growth Factor for Alveolar Bone Defect Repair","* Inclusion Criteria:\n* Preoperative CBCT imaging confirming mandibular third molars (M3s) with low to moderate impaction according to the Pell and Gregory classification, and not in the acute inflammatory stage.\n* Ipsilateral mandibular second molars (M2s) with retention value and no indication for extraction.\n* Patients able to provide written informed consent and willing to comply with the scheduled follow-up visits.\n* Age between 18 and 60 years (inclusive).\n* Exclusion Criteria:\n* Presence of systemic diseases or other contraindications to tooth extraction surgery.\n* Known or suspected current malignancy.\n* History of radiation therapy to the head and neck region.\n* History of chemotherapy within 5 years prior to surgery.\n* Smoking \\> 15 cigarettes per day.\n* Subjects with mental or neurological disorders, or otherwise unable to provide informed consent.","ALL","18 Years","60 Years",{"count":20,"type":21},136,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to combine real-world research with relevant bone repair materials and techniques to improve alveolar bone resorption in extraction sockets following impacted wisdom tooth removal, while achieving effective bone preservation or promoting bone regeneration. All eligible cases within specified parameters will be included in the clinical study scope. Based on real-world clinical data, we will proactively collect postoperative clinical examination findings and imaging data. Statistical analysis will be performed on clinical outcomes and follow-up data from patients undergoing mandibular impacted M3 extraction. The study aims to clarify the therapeutic efficacy of the thermosensitive hydroxyethylchitosan-loaded concentrated growth factor group in repairing mesial bone defects of M2s following M3 extraction.",[27,28,29],"Alveolar Bone Loss","Alveolar Ridge Resorption After Extraction","Tooth, Impacted","RECRUITING","2026-08-19",{"date":33,"type":34},"2026-08-21","ACTUAL",{"date":36,"type":34},"2024-08-01",{"date":38,"type":21},"2027-07-31",{"name":40,"class":41},"Stomatological Hospital Affiliated with Fujian Medical University","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":16,"minAge":17,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":42},"100615355","optimizing-pulp-management-in-autotransplantation-of-mature-third-molars-a-randomized-controlled-trial-100615355","NCT07291531","Optimizing Pulp Management in Autotransplantation of Mature Third Molars: A Randomized Controlled Trial","Optimizing Pulp Management Strategies for Autotransplantation of Fully Developed Third Molars: A Three-Arm Randomized Controlled Trial","OPuM-ATM3","Inclusion Criteria:\n\n1. Aged 18-40 years.\n2. Requires extraction of a non-restorable first or second molar AND possesses a fully developed, morphologically healthy ipsilateral third molar as a donor tooth.\n3. Willing and able to provide written informed consent.\n\nExclusion Criteria:\n\n1. Presence of acute infection or insufficient bone volume at the recipient site.\n2. Donor tooth exhibits caries, periapical pathology, or periodontal disease.\n3. Uncontrolled systemic disease (e.g., diabetes, immunosuppression), pregnancy, or lactation.\n\n   Smoking habit of \\>10 cigarettes per day.\n4. Inability or unwillingness to comply with the long-term follow-up schedule.",true,"40 Years",{"count":54,"type":21},360,[24],"This study aims to find the best way to use your own healthy wisdom tooth to replace the bad tooth. After transplantation, how to manage the \"tooth nerve\" (dental pulp) inside the tooth is a key question. Currently, doctors have three different management strategies, but it is not clear which one is most beneficial for long-term success.\n\nThis study will compare these three strategies:\n\nPerforming standard root canal treatment (removing the tooth nerve) a few weeks after transplantation.\n\nPerforming a special procedure to treat and fill the root tip during the transplant surgery, followed by root canal treatment later.\n\nSimply trimming the root tip during the transplant surgery, hoping to preserve the vitality of the tooth nerve and thereby avoid subsequent root canal treatment.\n\nIf you agree to participate, you will be randomly assigned to one of these groups to receive treatment. Afterwards, we will need to schedule regular check-ups for you over a period of 5 years (including X-rays and examinations) to monitor the healing of the transplanted tooth, check for any problems, and assess the status of the tooth nerve.\n\nYour participation will help us identify the most effective and long-lasting treatment method, thereby benefiting future patients in similar situations.",[58,59,29],"Tooth Avulsion","Dental Pulp Diseases",[61,62,63,64,65,66],"Autotransplantation","Third molar","Root canal therapy","Apical surgery","Root-end resection","mature tooth","NOT_YET_RECRUITING","2025-12-07",{"date":70,"type":34},"2025-12-18",{"date":72,"type":21},"2026-01",{"date":74,"type":21},"2032-06",{"name":76,"class":41},"Second Affiliated Hospital, School of Medicine, Zhejiang University",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":51,"sex":16,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":22,"phases":89,"briefSummary":90,"conditions":91,"keywords":97,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":109,"leadSponsor":111,"locationsCount":42},"100575923","comparison-of-piezoelectric-and-conventional-surgery-for-germectomy-of-the-lower-third-molar-100575923","NCT06778590","Comparison of Piezoelectric and Conventional Surgery for Germectomy of the Lower Third Molar","Comparison of Piezoelectric and Conventional Surgery for Germectomy of the Lower Third Molar: Assessment of Post-operative Sequelae","Germectomy","Inclusion Criteria:\n\n* Patients aged between 14 and 24 years, with both lower third molars in the developmental stage (with incompletely formed roots) and requiring extraction of both for prophylactic, therapeutic or strategic reasons\n* Good quality of radiographic investigations (CBCT)\n* Good health status","14 Years","24 Years",{"count":88,"type":21},22,[24],"The main objective of the study is to compare the effects of the piezoelectric surgery and the traditional technique on soft tissue edema in patients undergoing bilateral germectomy of mandibular third molars",[92,93,94,95,58,96,83],"Tooth Disease","Piezoelectric Technique","Tooth Impacted","Tooth Extraction Status Nos","Facial Swelling",[98,99,100,101,102,103,104],"third molar surgery","facial swelling","3D facial swelling evaluation","Piezoelectric technique","tooth impacted","piezosurgery","germectomy","2025-01-15",{"date":107,"type":34},"2025-01-16",{"date":36,"type":34},{"date":110,"type":21},"2025-10-31",{"name":112,"class":41},"Amerigo Giudice",{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":4,"eligibilityCriteria":119,"healthyVolunteers":51,"sex":16,"minAge":120,"maxAge":121,"enrollmentInfo":122,"targetDuration":4,"studyType":22,"phases":124,"briefSummary":125,"conditions":126,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":42},"100560233","impacted-canine-and-mixed-reality-technology---rct-100560233","NCT06574477","Impacted Canine and Mixed-reality Technology - RCT","Alignment of an Impacted Canine Using Mixed-reality HoloLens 2 Goggles - a Randomized Clinical Trial","Inclusion Criteria:\n\n* Healthy boys\u002Fmen and girls\u002Fwomen aged between 10 and 20 years.\n* Palatally impacted canine on one side\n* Axis of the canine \\> 10 degrees to the midline as measured on a pantomographic radiograph\n* During orthodontic treatment, in preparation for alignment of the impacted canine with adequate space for the retained canine\n\nExclusion Criteria:\n\n* Dental abnormalities (hyperodontia, hypodontia, etc.)\n* Impacted canines bilaterally\n* Previous trauma to the teeth or face\n* Congenital craniofacial malformations\n* Systemic diseases that would hinder orthodontic treatment\u002Foperation\n* Recent radiotherapy","10 Years","20 Years",{"count":123,"type":21},72,[24],"The goal of this clinical trial is to determine whether the use of HoloLens 2 mixed reality goggles for planning alignment of palatally impacted canine reduces: 1) treatment time and 2) the risk of complications compared to planning alignment of palatally impacted canine without HoloLens 2 goggles.\n\nParticipants will have an impacted canine on palatal side.\n\nResearchers will use or will not use HoloLens 2 goggles in planning therapy\n\nParticipants will wear fixed orthodontic appliances for the treatment of impacted canine. During treatment, attachment will fixed to an impacted canine and the direction of traction will be established.",[29],"2024-08-25",{"date":129,"type":34},"2024-08-28",{"date":131,"type":34},"2021-10-01",{"date":133,"type":21},"2027-10",{"name":135,"class":41},"Piotr Fudalej"]