[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"tracheostomized-patients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:tracheostomized-patients":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,53,86,108],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":35,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100647853","effects-of-a-perma-h-model-mobile-based-rehabilitation-support-program-on-hope-self-efficacy-perceived-social-support-and-rehabilitation-outcomes-in-post--tracheostomy-oral-cancer-patients-100647853",false,"NCT07714967","Effects of a Perma-h Model Mobile-based Rehabilitation Support Program on Hope, Self-efficacy, Perceived Social Support and Rehabilitation Outcomes in Post- Tracheostomy Oral Cancer Patients","Inclusion Criteria:\n\n* Aged ≥18 years\n* Pathologically diagnosed with oral squamous cell carcinoma and undergoing, or scheduled to undergo, tracheostomy followed by decannulation\n* Fully conscious, with a Glasgow Coma Scale score of 15, and able to successfully complete the Three-Step Command Test, indicating intact comprehension ability\n* Able to communicate effectively through verbal speech or alternative methods, including writing, gestures, electronic device input, or voice-assisted tools\n* Able to use WeChat independently or after brief guidance, without communication barriers\n* Has at least one regular family caregiver; both the patient and caregiver fully understand the study content and voluntarily provide written informed consent\n* Free from severe cardiovascular, cerebrovascular, hepatic, renal, or pulmonary disease\n\nExclusion Criteria:\n\n* Presence of other serious malignancies or extensive tumor metastasis\n* Previous or current diagnosis of severe mental illness, such as schizophrenia or severe bipolar disorder\n* Significant cognitive impairment, severe depressive symptoms, or suicide risk that precludes effective participation in psychological interventions\n* Inability to complete assessments or interventions due to severe hearing, visual, or language impairments\n* Inability to communicate effectively through any available alternative means\n* Lack of access to a smartphone and absence of a designated caregiver\n* Explicit unwillingness or inability to use a mobile-based rehabilitation support program\n* Unexpected inability to complete the full intervention cycle, including planned hospital transfer or prolonged loss to follow-up\n* Concurrent participation in other clinical studies primarily focused on psychological or mobile health interventions that could confound study outcomes","ALL","18 Years",{"count":18,"type":19},100,"ESTIMATED","INTERVENTIONAL",[22],"NA","The goal of this study (exploratory sequential design; mixed-methods study) is to evaluate whether a PERMA-H model mobile-based rehabilitation support program delivered to post-tracheostomy oral cancer patients can improve psychological and rehabilitation outcomes, compared with a control group receiving usual care\u002Fstandard support. The study will focus on post-tracheostomy oral squamous cell carcinoma (OSCC) patients (aged ≥18 years) who are undergoing or scheduled to undergo tracheostomy followed by decannulation, and who have adequate communication ability and caregiver support.\n\nThe main questions it aims to answer are:\n\nDoes the PERMA-H model mobile-based rehabilitation support program improve patients' hope? (primary hypothesis\u002Foutcome measure 1) Does the PERMA-H model mobile-based rehabilitation support program improve patients' self-efficacy, perceived social support, and rehabilitation outcomes? (primary hypothesis\u002Foutcome measure 2) If there is a comparison group, researchers will compare the PERMA-H model mobile-based rehabilitation support program (intervention group) to a control group receiving standard\u002Fusual care (control group) to determine differences in outcomes between groups.\n\nParticipants will be asked to complete the main study tasks, including:\n\nparticipating in qualitative interviews to explore their digital needs, expectations, and experiences regarding psychosocial care (Phase I); using the WeChat mini-program platform that incorporates a PERMA-H evidence-based module set and a chatbot (Decannulationbot \u002F Digital rehabilitation Assistant, DDA) as part of the rehabilitation support program; completing validated assessments at study endpoints to measure hope (Herth Hope Index), self-efficacy (General Self-Efficacy Scale), and perceived social support (Perceived Social Support Scale), as well as rehabilitation-related outcomes (including rehabilitation willingness\u002Fparticipation and functional measures such as swallowing function and speech intelligibility as rated by speech-language pathologists).\n\nExpected outcomes include: comprehensive qualitative findings to inform the content and delivery of digital psychosocial support; a functional mobile intervention platform with evidence-based modules validated through expert appraisal and pilot testing; and statistically significant improvements in hope, self-efficacy, perceived social support, and rehabilitation outcomes in the intervention group compared with the control group.",[25,26,27,28,29,30,31,32,33,34],"Tracheostomized Patients","Decanulation","Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer","Rehabilitation Outcome","Mental Health","Hope","Self Efficacy","Perceived Social Support","Swallowing Function","Speech Intelligibility",[36,37,38,39],"PERMA-H","chatbot","Digital Rehabilitation Support","MODEL MOBILE","NOT_YET_RECRUITING","2026-07-15",{"date":43,"type":44},"2026-07-20","ACTUAL",{"date":46,"type":19},"2026-08-01",{"date":48,"type":19},"2027-02-01",{"name":50,"class":51},"Hainan Medical College","OTHER",2,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":20,"phases":63,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":85},"100635969","high-flow-tracheal-oxygen-for-weaning-of-tracheostomized-patients-100635969","NCT07559591","High Flow Tracheal Oxygen for Weaning of Tracheostomized Patients","High Flow Tracheal Oxygen for Weaning of Tracheostomized Mechanically Ventilated Patients: A Pilot Randomised Controlled Trial (HFTO WEAN Trial)","HFTO-WEAN","Inclusion Criteria:\n\n1. Adults ≥ 18 years of age\n2. Intensive care unit (ICU) patients with tracheostomy inserted during the index ICU admission.\n3. Mechanically ventilated for ≤60 days.\n4. Successful spontaneous breathing trial for 1 hour.\n\nExclusion Criteria:\n\n1. Planned tracheostomy post head and neck surgery with ICU stay less than 48 hours\n2. Patient transferred from another hospital only if the intubation and tracheostomy dates are unavailable, otherwise would be eligible.\n3. Patient with an imminent plan for palliation and comfort care.\n4. Patient or substitute decision-maker declines consent to the study.\n5. The treating physician declines consent to the study.",{"count":62,"type":19},88,[22],"In this pilot randomized controlled trial (RCT), the investigators aim to explore the feasibility of conducting a powered RCT that examines the efficacy and safety of high flow tracheal oxygen (HFTO) in weaning critically ill tracheostomy patients from mechanical ventilation.\n\nObjective of the study\n\n1. To assess the feasibility of conducting a larger RCT as primary objective.\n2. To explore the effect of using HFTO in mechanically ventilated tracheostomized critically ill patients on ventilator-free days (VFD) compared to standard of care method using tracheal mask (TM) as secondary objective.",[25,66,67],"Mechanical Ventilation Weaning","High Flow Oxygen Therapy",[69,70,71,72,73,74],"tracheostomized patients","tracheostomy","mechanical ventilation weaning","high flow tracheal oxygen","mechanical ventilation liberation","critically ill","RECRUITING","2026-05-29",{"date":78,"type":44},"2026-06-02",{"date":80,"type":44},"2026-05-17",{"date":82,"type":19},"2027-05",{"name":84,"class":51},"King Faisal Specialist Hospital & Research Center",1,{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":92,"eligibilityCriteria":93,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":94,"targetDuration":4,"studyType":20,"phases":96,"briefSummary":97,"conditions":98,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":85},"100585050","high-flow-tracheal-therapy-on-tracheobronchial-secretions-in-tracheostomized-patients-100585050","NCT06897319","High-Flow Tracheal Therapy on Tracheobronchial Secretions in Tracheostomized Patients","Impact of High-Flow Tracheal Therapy on the Rheological Properties of Tracheobronchial Secretions in Tracheostomized Patients: A Randomized Crossover Study.","TRACH2O","Inclusion Criteria:\n\n* Adult patients (≥18 years old)\n* Tracheostomized patients\n* Patients requiring routine tracheal suctioning and already using HFT overnight\n\nExclusion Criteria:\n\n* Insufficient secretions for analysis\n* Cognitive impairment or confusion",{"count":95,"type":19},15,[22],"This monocentric, randomized crossover study aims to assess the impact of high-flow tracheal therapy (HFT) on the rheological properties of tracheobronchopulmonary secretions in tracheostomized patients. The primary objective is to compare the viscoelastic characteristics of secretions collected with and without HFT. Secondary objectives include evaluating the effects of HFT on dyspnea, patient comfort, and secretion appearance. The study will take place at Cliniques Universitaires Saint-Luc, with adult tracheostomized patients undergoing standard care.",[25],"2026-04-22",{"date":101,"type":44},"2026-04-27",{"date":103,"type":19},"2026-06-20",{"date":105,"type":19},"2027-08-01",{"name":107,"class":51},"Cliniques universitaires Saint-Luc- Université Catholique de Louvain",{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":114,"eligibilityCriteria":115,"healthyVolunteers":11,"sex":15,"minAge":4,"maxAge":4,"enrollmentInfo":116,"targetDuration":4,"studyType":118,"phases":4,"briefSummary":119,"conditions":120,"keywords":4,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":85},"100628864","invasive-home-ventilation-in-denmark-100628864","NCT07467187","Invasive Home Ventilation in Denmark","The Evolution of Invasive Home Mechanical Ventilation in Denmark","HOMEVENT DK","Inclusion Criteria:\n\n* Patients are included if they have or have had a respiratory certified personale care assistent during the period 2016-2025.\n\nExclusion Criteria:\n\n* Not tracheostomized\n* Tracheostomized but on spontaneous breathing throughout 1 January 2016 - 31 December 2025\n* Not discharged to home, assisted living, nursing home, or rehabilitation during 1 January 2016 - 31 December 2025",{"count":117,"type":19},450,"OBSERVATIONAL","The aim of this study is to describe national trends over the past 10 years in patients receiving invasive home mechanical ventilation (HMV) in Denmark. This includes indications for invasive HMV, diagnostic groups, and one-year mortality.",[121,122,123,124,125,126,25,127],"Neuromuscular Diseases (NMD)","ALS (Amyotrophic Lateral Sclerosis)","Spinal Cord Injuries (SCI)","Duchenne Muscular Dystrophy (DMD)","SMA - Spinal Muscular Atrophy","MSA - Multiple System Atrophy","Tracheostomy","2026-04-15",{"date":130,"type":44},"2026-04-20",{"date":132,"type":44},"2026-04-13",{"date":134,"type":19},"2028-09-01",{"name":136,"class":51},"Rigshospitalet, Denmark"]