[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"transcranial-random-noise-stimulation-trns\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:transcranial-random-noise-stimulation-trns":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100656642","transcranial-random-noise-trns-for-bpsd-in-alzheimers-disease-a-double-blind-randomized-controlled-trial-100656642",false,"NCT07827196","Transcranial Random Noise (tRNS) for BPSD in Alzheimer's Disease: A Double-blind Randomized Controlled Trial","Transcranial Random Noise (tRNS) for Behavioral and Psychological Symptoms in Alzheimer's Disease (BPSD): A Randomized, Double-blind, Sham-Controlled Trial","Inclusion Criteria:\n\n* Subject diagnosed with early Alzheimer's disease or related diseases according to NINCDS-ACDRADA criteria.\n* Subjects must have a MMSE score between 10 and 27,indicating mild cognitive impairment or dementia\n* CDR score ≤ 2\n* Subject under treatment by IAChE for at least 3 months.\n* psychotropic treatments are tolerated if they were administered and unchanged for at least 3 months\n\nExclusion Criteria:\n\n* NPI ≥ 4\n* CDR \\> 2\n* Any history or clinical signs of other severe psychiatric illnesses (like major depression,psychosis or obsessive compulsive disorder).\n* History of head injury,stroke,or other neurologic disease.\n* Organic brain defects on T1 or T2 images.\n* History of seizures or unexplained loss of consciousness.\n* Implanted pacemaker,medication pump,vagal stimulator,deep brain stimulator.\n* Family history of medication refractory epilepsy.\n* History of substance abuse within the last 6 months.","ALL","45 Years","84 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","To investigate the treatment effect of Transcranial random noise (tRNS) on Alzheimer patients, and the underlying neural mechanism by EEG.",[27,28,29,30],"Transcranial Random Noise Stimulation (tRNS)","Electroencephalography","Alzheimer Disease","BPSD (Behavioral and Psychological Symptoms of Dementia)",[32,33,29,34],"Transcranial random noise","electroencephalography","BPSD (behavioral and psychological symptoms of dementia)","RECRUITING","2026-09-14",{"date":38,"type":39},"2026-09-18","ACTUAL",{"date":41,"type":39},"2026-09-01",{"date":43,"type":21},"2027-09-01",{"name":45,"class":46},"Anhui Medical University","OTHER"]