[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"transradial-carotid-artery-stenting\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:transradial-carotid-artery-stenting":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100621961","safety-and-efficacy-of-a-novel-composite-tip-guiding-catheter-in-transcarotid-artery-stenting-via-transradial-access-100621961",false,"NCT07377422","Safety and Efficacy of a Novel Composite-Tip Guiding Catheter in Transcarotid Artery Stenting Via Transradial Access","Safety and Efficacy of a Novel Composite-Tip Guiding Catheter in Transcarotid Artery Stenting Via Transradial Access: A Prospective, Multicenter, Randomized Controlled Trial","Inclusion Criteria:\n\n1. Age ≥18 years;\n2. Patients who are candidates for endovascular intervention with CTA-confirmed stenosis in the common carotid artery or C1 segment of internal carotid artery(Symptomatic: ≥50% stenosis; Asymptomatic: 70%-99% stenosis）（NASCET criteria) ;\n\n   * Symptomatic carotid artery stenosis: Non-disabling ischemic stroke or transient ischemic symptoms (TIA, including hemispheric events or transient monocular blindness) within 180 days prior to randomization;\n\n     * Asymptomatic Carotid Stenosis: No history or examination findings suggestive of ipsilateral carotid ischemic symptoms(Non-carotid symptoms, contralateral carotid symptoms, symptom onset \\>180 days prior to randomization, or vertebrobasilar symptoms are classified as asymptomatic).\n3. Palpable radial pulse and negative Allen's test (confirming adequate ulnar collateral circulation);\n4. Feasible transradial access with achievable device delivery to the target lesion per operator assessment;\n5. Patients or legally authorized representatives comprehend the study purpose, voluntarily participate with signed informed consent, and commit to complete follow-up.\n\nExclusion Criteria:\n\n1. Patients with severe vascular tortuosity\u002Fdissection, extensive or diffuse atherosclerotic lesions involving the aortic arch or proximal common carotid artery, or post-surgical anatomy impeding catheter delivery;\n2. Severe stenosis, aneurysms ≥5mm in maximum diameter, arteriovenous malformations (AVM), or other significant cerebrovascular diseases in ipsilateral intracranial\u002Fextracranial arteries beyond the target vessel;\n3. Patients requiring simultaneous bilateral carotid interventions;\n4. Contraindicated in patients with severe allergies to interventional devices or agents related to carotid stenting (e.g., lidocaine, contrast agents, aspirin, clopidogrel);\n5. Preprocedural mRS ≥3;\n6. Progressive stroke within 2 weeks, hemorrhagic transformation of ischemic stroke within 3 months, or spontaneous intracranial hemorrhage within 12 months;\n7. Severe hematologic disorders (active bleeding, severe anemia, coagulopathy, or transfusion dependency), severe heart failure, severe hepatic\u002Frenal impairment, or acute coronary syndrome;\n8. Malignancy or life expectancy \\\u003C1 year.","ALL","18 Years",{"count":19,"type":20},204,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to evaluate the safety and efficacy of the novel composite-tip guiding catheter for transradial access in Carotid Artery Stenting procedures",[26,27],"Transradial Carotid Artery Stenting","Novel Composite-tip Guiding Catheter","RECRUITING","2026-09-30",{"date":31,"type":32},"2026-10-05","ACTUAL",{"date":34,"type":32},"2026-05-01",{"date":36,"type":20},"2027-08-16",{"name":38,"class":39},"Beijing Anzhen Hospital","OTHER"]