[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"traumatic-peripheral-nerve-injury\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:traumatic-peripheral-nerve-injury":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100647169","high-intensity-peripheral-magnetic-stimulation-in-traumatic-peripheral-nerve-injury-100647169",false,"NCT07705490","High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve Injury","Clinical and Electrophysiological Evaluation of the Effect of High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve Injury: A Randomized, Double-Blind, Sham-Controlled Trial","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Traumatic peripheral nerve injury\n* Unilateral traumatic peripheral neuropathy confirmed by electromyography (EMG)\n* Nerve injury occurring at least 3 months prior\n* Douleur Neuropathique 4 (DN4) score ≥ 4\n* Visual Analog Scale (VAS) score ≥ 4\n* Manual Muscle Testing score \\\u003C 5\n* No analgesic use, or stable analgesic therapy for the past month (no dose changes)\n\nExclusion Criteria:\n\n* Active infection or malignancy\n* Metal implant or shrapnel in the application area\n* Electronic implants (e.g., cardiac pacemaker, spinal cord stimulator, deep brain stimulator)\n* Central nervous system diseases\n* Non-traumatic causes of neuropathy (e.g., radiculopathy, diabetic neuropathy, entrapment neuropathies, HIV-related neuropathy, trigeminal neuralgia)\n* Complete nerve injury\n* Injury involving three or more peripheral nerves or plexus injury\n* History of peripheral nerve surgery or injection within the past 3 months\n* Active psychiatric illness\n* Coagulopathy","ALL","18 Years","65 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","Traumatic peripheral nerve injury is a common cause of chronic neuropathic pain, muscle weakness, and functional limitation, particularly in young and active individuals. Current conservative and pharmacological treatments often provide incomplete relief or carry side effects. High-intensity peripheral magnetic stimulation (PMS) is a non-invasive method that may help reduce neuropathic pain and support motor recovery, but evidence in traumatic nerve injury is limited.\n\nThis randomized, double-blind, sham-controlled trial aims to evaluate whether high-intensity PMS, added to a standardized therapeutic exercise program, improves pain, function, quality of life, and electrophysiological measures in adults with traumatic peripheral nerve injury. Participants will be randomly assigned to receive either active PMS or sham PMS, in addition to the same exercise program. Outcomes will be assessed at baseline, 4 weeks, and 8 weeks.",[27,28,29,30],"Peripheral Nerve Injuries","Traumatic Peripheral Nerve Injury","Neuropathic Pain","Peripheral Nerve Injuries, Traumatic",[32,33,29,34,35,36,37],"Peripheral Magnetic Stimulation","High-Intensity Magnetic Stimulation","Nerve Injury","Rehabilitation","Electrophysiology","Sham-Controlled Trial","NOT_YET_RECRUITING","2026-07-13",{"date":41,"type":42},"2026-07-15","ACTUAL",{"date":44,"type":21},"2026-08",{"date":46,"type":21},"2027-07",{"name":48,"class":49},"Gaziler Physical Medicine and Rehabilitation Education and Research Hospital","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":16,"minAge":58,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":70,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":5},"100579773","comparing-digitally-and-traditionally-made-ankle-foot-orthoses-100579773","NCT06828653","Comparing Digitally and Traditionally Made Ankle Foot Orthoses","Feasibility RCT Evaluating Digitally and Traditionally Produced Ankle Foot Orthoses for Individuals With Impaired Lower Limb Function","Inclusion Criteria:\n\n* Participants must be aged 8 years or older.\n* Participants should have either flaccid or spastic paresis resulting from conditions such as cerebral palsy, stroke, spinal cord injury, spina bifida, or traumatic peripheral nerve injury, leading to lower limb mobility impairments.\n* Participants must require a custom articulating, rigid, or energy storage and return (ESR) AFO to improve physical function for one or both sides (unilateral or bilateral).\n* Participants must be able to ambulate independently, though the use of gait aids is permitted.\n* Participants must be capable of completing questionnaires with no more than orienting guidance.\n* Participants must meet the requirements to have their AFO funded by the Assistive Devices Program (ADP).\n\nExclusion Criteria:\n\n* Clients for whom the primary goal of the AFO includes wound management.\n* Those whose AFO is not worn for ambulation.\n* Clients with insensate feet or a history of ulcerations.\n* First-time AFO users.","8 Years",{"count":60,"type":21},50,[24],"The research is being done to compare two methods of creating AFOs: 1. The traditional method, which involves manually creating a mold from a plaster cast of the client's limb. This is time-consuming and labor-intensive; and 2. The newer method uses digital technology, such as 3D scanning and printing, to design and produce the AFOs, potentially making the process faster and less costly. We want to know whether AFOs made using digital technology can provide the same clinical benefits as those made traditionally.",[64,65,66,67,68,69,28],"Flaccid Paresis","Spastic Paresis","Cerebral Palsy","Stroke","Spinal Cord Injury","Spina Bifida",[71,72,73,74,75,76,77],"Ankle foot orthosis","ankle foot orthoses","digital ankle foot orthoses","digital technology","3D scanning","3D printing","randomized control trial","RECRUITING","2025-11-18",{"date":81,"type":42},"2025-11-20",{"date":83,"type":42},"2025-09-05",{"date":85,"type":21},"2027-03-31",{"name":87,"class":49},"Holland Bloorview Kids Rehabilitation Hospital"]