[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"unilateral-transfemoral-amputation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:unilateral-transfemoral-amputation":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100651914","a-comparison-between-ischial-containment-and-sub-ischial-prosthetic-sockets-to-determine-their-effects-on-secondary-health-conditions-100651914",false,"NCT07768072","A Comparison Between Ischial-Containment and Sub-Ischial Prosthetic Sockets to Determine Their Effects on Secondary Health Conditions","Inclusion Criteria:\n\nFor all participants:\n\n* Ability to complete the experimental protocol without undue fatigue or health risks\n* Low Back Pain scale assessment (0-10) less than 4 (activities of daily living or quality of life not impacted)\n\nIn addition for persons with lower limb amputation:\n\n* Prosthesis user for a minimum of 2 years with their current socket design\n* Good fit with either an ischial containment (IC) or sub-ischial (SI) socket\n* Good skin integrity on their residual limb upon visual inspection\n* Does not require the use of assistive devices to walk\n\nExclusion Criteria:\n\n* Previously diagnosed with a spine condition (e.g., pinched nerve, bulging disc, etc.)\n* Previously diagnosed with an orthopedic or neuromuscular condition that may affect walking or balance (e.g., ankle fusion, Parkinson's disease, stroke, etc.)",true,"ALL","18 Years","70 Years",{"count":20,"type":21},45,"ESTIMATED","OBSERVATIONAL","Long-term above-knee prosthesis users are at an increased risk of developing secondary musculoskeletal conditions compared to the general able-bodied population. One secondary physical concern is low back pain (LBP), for which the development is not entirely understood, but in above-knee prosthesis users it is believed to relate to asymmetries and compensations that are typically demonstrated and required to stand and walk. Understanding spinal motion and compensations will enhance our knowledge of the factors contributing to LBP, and possibly lead to the development of new prosthetic and therapeutic interventions to prevent or alleviate LBP, thereby improving mobility and quality of life for prosthesis users.",[25],"Unilateral Transfemoral Amputation",[27,28,29],"transfemoral amputation","prosthetic socket design","low back pain","NOT_YET_RECRUITING","2026-08-12",{"date":33,"type":34},"2026-08-17","ACTUAL",{"date":36,"type":21},"2027-01-01",{"date":38,"type":21},"2030-12-31",{"name":40,"class":41},"VA Office of Research and Development","FED",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":42},"100596724","real-time-motion-capture-and-visual-feedback-for-amputation-gait-training-100596724","NCT07049198","Real-time Motion Capture and Visual Feedback for Amputation Gait Training","The Effect of a Real-time 2D Motion Capture and Visual Feedback Gait Training Systems on Walking Performance in People With Unilateral Transfemoral Amputation","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Individuals with unilateral transfemoral amputation or knee disarticulation\n* Wear a prosthesis for at least 3 hours per day\n* Have been using a prosthesis for more than 6 months\n* Medicare Functional Classification Level (K-level) of 2 or above\n* Able to walk independently for 5 meters without assistive devices\n* No pain caused by poor prosthetic fit\n* Montreal Cognitive Assessment Taiwan Version (MoCA-T) score ≥ 26\n\nExclusion Criteria:\n\n* Uncontrolled systemic diseases (e.g., diabetes mellitus, hypertension)\n* Cardiopulmonary or cardiovascular diseases (e.g., heart failure, severe asthma)\n* History of neurological conditions that affect movement (e.g., stroke, spinal cord injury, cerebellar injury)\n* Vestibular disorders\n* Severe osteoporosis\n* Other musculoskeletal injuries or open wounds\n* Epilepsy\n* Uncorrected visual impairments\n* Congenital limb deficiency","65 Years",{"count":52,"type":21},40,"INTERVENTIONAL",[55],"NA","People with transfemoral amputation face challenges such as gait asymmetry, instability, and increased energy consumption due to loss of the knee joint. Because of the loss of proprioceptive feedback from their missing limbs, visual feedback is essential for gait correction. Additionally, current visual feedback systems lack portability, cost-effectiveness, and they fail to provide precise, intuitive feedback on spatiotemporal parameters, joint angles, and both frontal and sagittal plane information, limiting their effectiveness in correcting gait abnormalities.This study aims to investigate whether gait training using a real-time 2D motion capture and visual feedback gait training system (2DMV) can improve the gait biomechanics and psychosocial functions of people with unilateral transfemoral amputation (uTFA). The 2DMV system analyzes spatiotemporal parameters and joint kinematics during gait and displays the uTFA's image on a screen, providing visual feedback specifically targeting gait abnormalities. This allows individuals with uTFA to intuitively understand the feedback and make real-time gait adjustments. The biomechanical parameters include joint kinematics, gait symmetry, and walking performance.",[25,58],"Unilateral Knee Disarticulation","2025-07-01",{"date":61,"type":34},"2025-07-03",{"date":63,"type":21},"2025-07-15",{"date":65,"type":21},"2027-07-31",{"name":67,"class":68},"National Yang Ming Chiao Tung University","OTHER"]