[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"unruptured-intracranial-wide-neck-bifurcation-aneurysms\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:unruptured-intracranial-wide-neck-bifurcation-aneurysms":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100647326","flow-diverter-versus-conventional-endovascular-treatment-for-unruptured-wide-neck-bifurcation-aneurysms-fd-bwa-trial-100647326",false,"NCT07707076","Flow Diverter Versus Conventional Endovascular Treatment for Unruptured Wide-Neck Bifurcation Aneurysms (FD-BWA Trial)","Traditional Approach Versus Flow Diverter for Unruptured Intracranial Wide-neck Bifurcation Aneurysms: a Prospective International Multicenter Randomized Controlled Study (FD-BWA Study)","FD-BWA","Inclusion Criteria:\n\n1. Age 18-75 years;\n2. Diagnosis of unruptured intracranial, bifurcation, saccular, wide-neck aneurysm by DSA\u002FCTA\u002FMRA;\n3. Patients who can understand the purpose of the trial, voluntarily participate and sign the informed consent form.\n\nExclusion Criteria:\n\n1. Patients with two or more multiple aneurysms that all require treatment within 1 year;\n2. Concomitant cerebrovascular diseases such as arteriovenous malformation, moyamoya disease;\n3. Ruptured aneurysms and narrow-neck aneurysms;\n4. Patients who have had a stroke (cerebral hemorrhage, cerebral infarction) within the past 1 month;\n5. Extremely poor clinical condition, modified Rankin Score ≥3;\n6. Patients already scheduled for surgery\u002Finterventional procedure within 3 months;\n7. Patients deemed unsuitable for interventional treatment by the investigator (e.g., no suitable vascular access, excessively tortuous vessels, difficulty delivering stent);\n8. Patients unsuitable for anesthesia or endovascular surgery, such as major diseases of heart, lung, liver, spleen, kidney, brain tumors, severe active infections, disseminated intravascular coagulation, severe mental illness;\n9. Patients unable to receive antiplatelet or anticoagulant therapy;\n10. Patients who have had or may have severe reactions to contrast media precluding pre-treatment medication;\n11. Patients with a definite history of allergy to cobalt-chromium, nickel-titanium alloy materials;\n12. Participation in other drug or medical device clinical trials before enrollment without reaching the primary endpoint timeframe;\n13. Pregnant or breastfeeding women;\n14. Patient's life expectancy less than 12 months;\n15. Investigator judges that the patient has poor compliance and cannot complete the study as required.","ALL","18 Years","75 Years",{"count":21,"type":22},266,"ESTIMATED","INTERVENTIONAL",[25],"NA","Brief Summary：\n\nThe goal of this clinical trial is to compare whether the traditional approach (stent-assisted coiling) is associated with a lower complication rate than flow diverter (Pipeline™) treatment for unruptured intracranial wide-neck bifurcation aneurysms. It will also evaluate the long-term imaging outcomes and safety of both treatments. The main questions it aims to answer are:\n\n* Does the traditional approach result in a lower rate of any stroke or all-cause death within one year after treatment compared to the flow diverter?\n* What medical problems do participants experience during and after each treatment?\n* What are the imaging cure and stability rates at 1, 2, and 5 years after treatment?\n\nResearchers will compare the traditional approach (stent-assisted coiling) with the flow diverter (Pipeline™) to determine which treatment has better safety and efficacy outcomes.\n\nParticipants will:\n\n* Be randomly assigned to receive either the flow diverter or traditional stent-assisted coiling\n* Undergo the assigned endovascular procedure\n* Return for follow-up visits at 30 days, 6 months, 1 year, 2 years, and 5 years after surgery for clinical assessments and imaging examinations (DSA, MRA, or CTA)",[28],"Unruptured Intracranial Wide-neck Bifurcation Aneurysms",[30,31,32,33,34],"intracranial aneurysms","wide-neck","bifurcation","flow diverter","unruptured","RECRUITING","2026-07-10",{"date":38,"type":39},"2026-07-16","ACTUAL",{"date":41,"type":39},"2026-02-10",{"date":43,"type":22},"2030-06-30",{"name":45,"class":46},"Nanfang Hospital, Southern Medical University","OTHER"]