[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"upper-limb-deficit\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:upper-limb-deficit":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100642886","impact-of-vns-with-rehab-on-gait-post-stroke-100642886",false,"NCT07643337","Impact of VNS With Rehab on Gait Post-Stroke","The Impact of Vagus Nerve Stimulation Paired With Rehabilitation on Lower Limb and Gait Functions After Ischemic Stroke","Inclusion Criteria:\n\n* Approved for Vagus Nerve Stimulation (VNS) and rehabilitation therapy\n* ≥22 years and ≤ 80 years\n* Only patients who elect to undergo VNS therapy for stroke-related upper limb deficits\n* Residual active movement in the affected limb's thumb and other 2 fingers\n* Stroke-related deficits in the lower limbs and gait with a Functional Ambulation Category (FAC) ≥3\n* Able to follow simple instructions and independently walk short distances with or without external support or leg orthoses, but without manual contact with another person\n\nExclusion Criteria:\n\n* Intact lower limb functions (Fugl-Meyer score=34)\n* Not a candidate for VNS therapy according to FDA guidelines\n* Pregnant patients","ALL","22 Years","80 Years",{"count":20,"type":21},24,"ESTIMATED","INTERVENTIONAL",[24],"NA","This is a prospective, double-blinded, randomized controlled study to evaluate the impact of Vagus Nerve Stimulation (VNS) therapy on lower limb function.",[27,28,29],"Upper Limb Deficit","Stroke Gait Rehabilitation","Stroke",[31,32,33],"vagus nerve stimulation","stroke rehabilitation","stroke related upper limb deficit","RECRUITING","2026-06-08",{"date":37,"type":38},"2026-06-11","ACTUAL",{"date":40,"type":21},"2026-06",{"date":42,"type":21},"2028-02-23",{"name":44,"class":45},"State University of New York at Buffalo","OTHER"]