[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"urinary-dysfunction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:urinary-dysfunction":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,41,69],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100565105","sexual-and-urinary-function-improvement-for-cancer-survivors-100565105",false,"NCT06637852","Sexual and Urinary Function Improvement for Cancer Survivors","Sexual and Urinary Function Improvement for Cancer Survivors- Promoting Access to Collaborative Treatment (SUFICS-PACT)","Inclusion Criteria:\n\n* At least 18 years old\n* Have a diagnosis of prostate cancer\n* Have sought care\u002Ftreatment for prostate cancer\n\nExclusion Criteria:\n\n* Patients under 18 years old\n* Patients who have not sought care\u002Ftreatment for prostate cancer\n* Patients who are categorized as \"vulnerable subjects,\" such as minors or incarcerated individuals.","MALE","18 Years",{"count":19,"type":20},200,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this study is to test the efficacy of SUFICS-PACT to identify and treat sexual and urinary dysfunction in prostate cancer survivors at NYC H+ H\u002FBellevue, the oldest public hospital in the US. This study will evaluate the implementation of an adapted sexual and urinary function collaborative care model at NYC Health+Hospitals\u002FBellevue. The study will test the efficacy of this collaborative care model through a randomized controlled trial in the adult primary care clinic; the intervention arm will receive collaborative treatment consisting of a care manager who has specialty training in mental health and psychosexual counseling, a primary care nurse practitioner who leads symptom management, primary care physicians who supervise the team, and a team specialty consult liaison.",[26,27],"Urinary Dysfunction","Sexual Dysfunction","NOT_YET_RECRUITING","2026-07-29",{"date":31,"type":32},"2026-07-30","ACTUAL",{"date":34,"type":20},"2026-10-01",{"date":36,"type":20},"2030-03-31",{"name":38,"class":39},"NYU Langone Health","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":16,"minAge":17,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":55,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":4},"100648377","effects-of-pelvic-floor-muscle-training-combined-with-bladder-training-on-some-parametrs-of-men-with-urinary-frequency-100648377","NCT07719400","Effects of Pelvic Floor Muscle Training Combined With Bladder Training on Some Parametrs of Men With Urinary Frequency","Effects of Pelvic Floor Muscle Training Combined With Bladder Training on Urinary Frequency, Pelvic Floor Function, and Post-Void Residual Volume in Men With Urinary Frequency: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Male sex\n* Age 18-65 years\n* Complaint of urinary frequency persisting for at least 3 months\n* On a 3-day bladder diary: ≥8 voids per 24 hours\n* Provision of written informed consent Sufficient cognitive capacity to learn pelvic floor muscle contraction (assessed by clinical judgment)\n\nExclusion Criteria:\n\n* Active urinary tract infection\n* Prostate cancer\n* Prostate surgery within the last 12 months\n* Parkinson's disease, Multiple sclerosis (MS), Stroke, Spinal cord injury\n* Neurogenic bladder due to diabetes mellitus\n* Bladder stones, Bladder tumor, Urethral stricture",true,"60 Years",{"count":51,"type":20},120,[23],"This prospective, single-center, parallel-group, assessor-blinded randomized controlled trial will include 120 voluntary male participants who have had complaints of urinary frequency for at least 3 months and meet the inclusion criteria. Participants will be randomly allocated into two groups (Group 1: Bladder Training + Pelvic Floor Muscle Training; Group 2: Bladder Training Alone). Assessments will be repeated at baseline, at week 4, and at week 8. The primary outcome measure will be 3-day bladder diary data (24-hour voiding frequency); secondary outcomes will include the OAB-V8, ICIQ-OAB, and PGI-I scales, as well as transabdominal ultrasonographic measurements of bladder neck elevation (strength and endurance) and PVR.",[26],[56,57,58,59],"Pelvic Floor Muscle Training","Urinary Frequency","Pelvic Floor Function","Bladder Training","2026-07-18",{"date":62,"type":32},"2026-07-22",{"date":64,"type":20},"2026-09-01",{"date":66,"type":20},"2027-12-01",{"name":68,"class":39},"Bingol University",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":76,"minAge":17,"maxAge":4,"enrollmentInfo":77,"targetDuration":79,"studyType":80,"phases":4,"briefSummary":81,"conditions":82,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":4},"100431114","the-opera-study-evaluating-qol-after-rectal-cancer-surgery-100431114","NCT04893876","The OPERa Study: Evaluating QoL After Rectal Cancer Surgery","The OPERa Study: A Multicenter Observational Prospective Cohort Study to Evaluate Determinants of Long-Term Quality of Life Following Restorative Proctectomy for Rectal Cancer Treatment","Inclusion Criteria:\n\n* Patients \\>18 years with histopathologically confirmed adenocarcinoma of the rectum, defined as tumor ≤15cm from the anal verge who are planned for RP ± neoadjuvant treatment or WW (CRT alone without surgery).\n\nExclusion Criteria:\n\n* Metastatic disease at diagnosis;\n* Planned for abdominoperineal resection (APR), low Hartmann's or pelvic exenteration (PE);\n* Cannot be contacted by telephone;\n* Unable to read and comprehend English or French;\n* Unable to give clear and informed consent.","ALL",{"count":78,"type":20},1200,"3 Years","OBSERVATIONAL","Advances in rectal cancer management have significantly reduced morbidity and mortality. The most commonly performed operation for rectal cancer is restorative proctectomy (RP), leaving up to 70% with long-term bowel dysfunction called Low Anterior Resection Syndrome (LARS). LARS manifests as stool frequency, incontinence and difficult defecation. LARS, along with other functional impairments such as sexual and urinary dysfunction (SUD), can impact quality of life (QoL) and cause emotional distress. High-quality longitudinal data on these sequalae are lacking, leading to variable estimates of their prevalence, risk factors and prognosis. Most studies are European, cross-sectional, lack pre-treatment evaluation and long-term follow-up, and use inconsistent assessment measures. Thus, a North American study that evaluates patients longitudinally from diagnosis will provide quality data to fill this knowledge gap.\n\nThe main aim of the proposed study is to contribute evidence regarding the impact of LARS, SUD, emotional\u002Ffinancial distress, and patient activation on long-term post-treatment QoL in North American rectal cancer after RP.\n\nThis multicenter North American, observational, prospective cohort study relies on validated patient reported outcome measures (PROMs) at diagnosis, during and post-treatment. Patients from 20 sites will be recruited over 2 years and followed for 3 years. The primary endpoint is QoL as measured by the European Organization for Research \\& Treatment of Cancer QoL questionnaire. We anticipate accrual of 1200 patients. Factors associated with QoL will be explored. Impact of patient activation in relation to functional outcomes on QoL over time will be explored using a difference-in-differences approach. The study involves a multidisciplinary team who will provide expertise in research methodology, nursing, oncology and surgery.\n\nThe main contributions of this study are 1) provision of reference baseline North American values for important rectal cancer PROMs for clinical and research use, 2) an understanding of the evolution of functional outcomes and QoL post-treatment to counsel patients peri-operatively and throughout survivorship, and 3) to provide the basis for future tailored programs to support rectal cancer survivors.",[83,84,85,27,26,86,87],"Rectal Cancer","Quality of Life","Bowel Dysfunction","Emotional Distress","Surgery","2022-08-17",{"date":90,"type":32},"2022-08-18",{"date":92,"type":20},"2023-01-01",{"date":94,"type":20},"2029-09-30",{"name":96,"class":39},"Jewish General Hospital"]