[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"uromodulin\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:uromodulin":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":4},"100651553","uromodulin-as-a-biomarker-in-lupus-nephritis-100651553",false,"NCT07763834","Uromodulin as a Biomarker in Lupus Nephritis","Evaluation of Uromodulin as a Biomarker of Renal Histological Activity\u002F Chronicity Indices in Lupus Nephritis","Inclusion Criteria:\n\n* • Group I: 30 patients with different classes of Lupus Nephritis. These cases are biopsy proven\n\nLN. Histological diagnosis of LN is according to the revised International Society of\n\nNephrology\u002F Renal Pathology Society (ISN\u002FRPS) classification and modified National Institute of Health (NIH) activity and chronicity indices (Bajema et al 2018) .\n\n* Biopsy-proven lupus nephritis at the time of uromodulin blood sampling.\n* Group II: 10 patients with active SLE without renal involvement and with SLEDAI score ≥6\n* Group III: 10 patients with non-active SLE with SLEDAI score \\\u003C6\n* Group IV: 30 patients with primary forms of non-lupus Glomerulonephritis\n* Group V: 10 healthy control subjects\n* All cases are adults ≥18 years.\n* Diagnosis of systemic lupus erythematosus according to the 2019 EULAR\u002FACR Classification\n\nCriteria (Ref).Exclusion Criteria:\n\n* • .Pregnancy or lactation\n\n  * AKI secondary to pre renal OR post renal cause (from clinical history and imaging).\n  * End-stage renal disease requiring dialysis\n  * Active infection or sepsis\n  * Active malignancy (either under treatment or within 5 years of successful treatment)\n  * History of renal transplantation\n  * Heart failure with NYHA III and IV\n  * Hhistory of other autoimmune diseases or diabetes mellitus",true,"ALL","18 Years",{"count":20,"type":21},90,"ESTIMATED","OBSERVATIONAL","Evaluation of Uromodulin as a biomarker of renal histological activity\u002F Chronicity indices in lupus nephritis",[25,26],"Uromodulin","SLE","NOT_YET_RECRUITING","2026-08-09",{"date":30,"type":31},"2026-08-13","ACTUAL",{"date":33,"type":21},"2026-10-01",{"date":35,"type":21},"2030-03-03",{"name":37,"class":38},"Assiut University","OTHER"]