[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ventilatory-function\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ventilatory-function":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100648066","effect-of-thoracic-mobilization-in-people-with-central-obesity-100648066",false,"NCT07718178","Effect of Thoracic Mobilization in People With Central Obesity","Effect of Mulligan Thoracic Mobilization on Ventilatory Functions and Chest Wall Expansion in Central Obesity","Inclusion Criteria:\n\n* Males aged 25-35 years.\n* Presence of central obesity, defined as:\n\n  * Waist circumference ≥102 cm in males.\n  * Waist-hip ratio (WHR) ≥0.90 in males.\n* BMI from 30-39.9 kg\u002Fm².\n* Willing to comply with conventional physiotherapy (diet and exercise) and mobilization programs.\n* Medically stable individuals with a restrictive lung pattern (Normal FEV₁\u002FFVC ratio and FVC \\\u003C 80% of predicted).\n* Low level physical activity (using the International Physical Activity Questionnaire-Short Version).\n* Non-smokers.\n\nExclusion Criteria:\n\n* Diagnosed COPD, asthma, or other chronic respiratory diseases.\n* Recent thoracic spine or rib injury\u002Fsurgery.\n* Cardiovascular instability or uncontrolled hypertension.\n* Contraindications to manual therapy (e.g., osteoporosis, rib fractures, or spinal tumors).\n* Participation in any structured weight loss program or exercise regimen in the past 6 months.\n* History of bariatric surgery (e.g., gastric sleeve, gastric bypass).\n* Use of medications that affect body weight or metabolism (e.g., corticosteroids, antipsychotics, weight loss drugs).\n* Neurological or musculoskeletal conditions that limit mobility or exercise participation and interfere with gait.\n* Any acute respiratory infections in the past 6 weeks.","MALE","25 Years","35 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to learn whether Mulligan thoracic mobilization in extension improves ventilatory functions and chest wall expansion in adults with central obesity. It will also evaluate whether adding Mulligan thoracic mobilization to a low-carbohydrate diet and aerobic exercise provides greater benefits than diet and exercise alone.\n\nThe main questions it aims to answer are:\n\nDoes Mulligan thoracic mobilization improve ventilatory functions (FVC, FEV₁, FEV₁\u002FFVC ratio, and MVV) in adults with central obesity? Does Mulligan thoracic mobilization improve chest wall expansion, functional capacity, and health-related quality of life?\n\nResearchers will compare Mulligan thoracic mobilization combined with a low-carbohydrate diet and aerobic exercise to a low-carbohydrate diet and aerobic exercise alone to determine whether the addition of thoracic mobilization improves respiratory outcomes.\n\nParticipants will:\n\nBe randomly assigned to either the intervention group or the control group. Receive an individualized low-carbohydrate diet and supervised aerobic exercise for 8 weeks.\n\nReceive Mulligan thoracic mobilization in extension five times per week for 8 weeks if assigned to the intervention group.\n\nUndergo assessments of ventilatory functions, chest wall expansion, functional capacity, and quality of life before and after the intervention.",[27,28],"Central Obesity","Ventilatory Function","NOT_YET_RECRUITING","2026-07-28",{"date":32,"type":33},"2026-07-29","ACTUAL",{"date":35,"type":21},"2026-07-25",{"date":37,"type":21},"2027-02-10",{"name":39,"class":40},"Cairo University","OTHER"]