[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"video-assisted-thoracoscopic-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:video-assisted-thoracoscopic-surgery":187},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,50,76,100,127,151,174,200],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100649440","analgesia-with-transdermal-buprenorphine-patch-in-adults-undergoing-video-assisted-thoracoscopic-surgery-100649440",false,"NCT07733128","Analgesia With Transdermal Buprenorphine Patch in Adults Undergoing Video-Assisted Thoracoscopic Surgery","Analgesia With a 5 mcg\u002FHour Transdermal Buprenorphine Patch as Part of Multimodal Analgesia in Adults Undergoing Unilateral Video-Assisted Thoracoscopic Surgery: A Triple-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Scheduled for elective unilateral video-assisted thoracoscopic surgery (VATS).\n* American Society of Anesthesiologists (ASA) physical status I-III.\n* Able to understand the study procedures and provide written informed consent.\n\nExclusion Criteria:\n\n* Known allergy or hypersensitivity to buprenorphine or any component of the transdermal patch.\n* Chronic opioid use before surgery.\n* Severe hepatic impairment.\n* Pregnancy or breastfeeding.\n* Inability to complete postoperative pain assessments.\n* Any condition that, in the investigator's opinion, could interfere with study participation or outcome assessment.","ALL","18 Years",{"count":19,"type":20},90,"ESTIMATED","INTERVENTIONAL",[23],"NA","Postoperative pain remains a major challenge after video-assisted thoracoscopic surgery (VATS), despite the use of multimodal analgesia. This randomized, triple-blind, placebo-controlled clinical trial will evaluate whether adding a 5 mcg\u002Fhour transdermal buprenorphine patch to the standard multimodal analgesic regimen reduces postoperative pain in adults undergoing unilateral VATS. Participants will be randomly assigned to receive either transdermal buprenorphine or placebo in addition to standard analgesia. Postoperative pain will be assessed at 24, 48, and 72 hours and 7 days after surgery. Secondary outcomes include opioid rescue requirements, length of hospital stay, postoperative nausea and vomiting, pruritus, and urinary retention.",[26,27,28],"Postoperative Pain","Thoracic Surgery","Video-Assisted Thoracoscopic Surgery",[30,31,32,28,33,26,34,27,35,36],"Buprenorphine","Transdermal Patch","Multimodal Analgesia","VATS","Randomized Controlled Trial","Acute Pain","Opioid Analgesia","RECRUITING","2026-07-24",{"date":40,"type":41},"2026-07-29","ACTUAL",{"date":43,"type":41},"2026-03-01",{"date":45,"type":20},"2027-07",{"name":47,"class":48},"Clínica Dávila","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":4},"100645564","two-point-versus-single-point-serratus-anterior-plane-block-for-post-thoracoscopic-surgery-analgesia-100645564","NCT07700823","Two-Point Versus Single-Point Serratus Anterior Plane Block for Post-Thoracoscopic Surgery Analgesia","Comparison of Ultrasound-Guided Two-Point Combined vs Single-Point Serratus Anterior Plane Block for Postoperative Analgesia in Thoracoscopic Surgery: A Prospective Observational Cohort Study","Inclusion Criteria:\n\n* Aged 18 to 85 years at enrollment, regardless of sex\n* American Society of Anesthesiologists (ASA) physical status grade I to III\n* Scheduled for elective unilateral video-assisted thoracoscopic surgery\n* Planned to receive ultrasound-guided SAPB for routine perioperative analgesia\n* Able to understand study procedures and provide written informed consent\n\nExclusion Criteria:\n\n* Local infection or skin lesion at the block puncture site\n* Known hypersensitivity or allergy to amide local anesthetics\n* Preexisting sensory abnormality in the chest wall surgical area\n* Chronic opioid use for \\> 3 months, history of chronic pain syndrome, or history of opioid abuse\n* Severe coagulopathy (international normalized ratio \\> 1.5 or platelet count \\\u003C 80 × 10⁹\u002FL)\n* Cognitive impairment or inability to cooperate with postoperative pain assessment\n* Refusal to provide written informed consent","85 Years",{"count":59,"type":20},88,"OBSERVATIONAL","Postoperative pain remains a common clinical challenge in patients undergoing video-assisted thoracoscopic surgery (VATS), impairing early recovery and increasing opioid consumption. The serratus anterior plane block (SAPB) is a widely used regional analgesic technique for thoracic surgery, but conventional single-point injection may have limited spread of local anesthetics, resulting in suboptimal analgesia in some patients. Preliminary anatomical evidence suggests that two-point combined SAPB may achieve wider dermatomal coverage and better analgesic efficacy.\n\nThis is a single-center, prospective observational cohort study conducted at Shanghai Pulmonary Hospital, China. A total of 88 adult patients scheduled for elective unilateral VATS will be consecutively enrolled and naturally assigned to either the two-point combined SAPB group (injection at the 3rd and 5th rib levels, total 30 ml local anesthetic) or the single-point SAPB group (injection at the 5th rib level, 30 ml local anesthetic) according to routine clinical practice.\n\nThe primary outcome is the verbal rating scale (VRS) pain score on coughing at 24 hours postoperatively. Secondary outcomes include resting and dynamic pain scores at multiple time points, cumulative opioid consumption at 24 and 48 hours, incidence of postoperative nausea and vomiting, block-related complications, length of hospital stay, and Quality of Recovery-15 (QoR-15) scores. This study aims to provide clinical evidence for optimizing perioperative analgesic strategies for thoracoscopic surgery.",[63,64,28,65],"Lung Cancer","Pain","Serratus Anterior Plane Block","NOT_YET_RECRUITING","2026-07-08",{"date":69,"type":41},"2026-07-14",{"date":71,"type":20},"2026-08-01",{"date":73,"type":20},"2026-09-05",{"name":75,"class":48},"Shiyou Wei",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":21,"phases":86,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":99},"100630970","teas-for-ipsilateral-shoulder-pain-after-video-assisted-thoracoscopic-lung-surgery-100630970","NCT07494591","TEAS for Ipsilateral Shoulder Pain After Video-Assisted Thoracoscopic Lung Surgery","Preoperative Transcutaneous Electrical Acupoint Stimulation for Ipsilateral Shoulder Pain After Video-Assisted Thoracoscopic Lung Surgery: A Multi-Center, Single-Blind, Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients scheduled for unilateral thoracic surgery\n* Age ≥ 18 years, regardless of gender\n* ASA physical status classification I-III\n* No severe cardiopulmonary insufficiency or other major comorbidities\n\nExclusion Criteria:\n\n* Pre-existing shoulder pain or functional impairment\n* Severe mental illness or cognitive impairment\n* Bilateral thoracic surgery\n* Any other conditions deemed inappropriate by the investigators (with reasons to be documented)","99 Years",{"count":85,"type":20},216,[23],"Shoulder pain is a common problem after certain types of lung surgery called video-assisted thoracoscopic surgery (VATS). This study examines whether a treatment called transcutaneous electrical acupoint stimulation (TEAS) can help reduce this pain. TEAS is a non-invasive technique that uses mild electrical stimulation at specific points on the body.Patients who are having VATS lung surgery will be randomly assigned to either receive TEAS before surgery or standard care. Researchers will measure how much shoulder pain patients experience and compare the two groups.The goal is to see if TEAS can help patients feel less pain and recover better after this type of lung surgery.",[89,28],"Ipsilateral Shoulder Pain","2026-03-20",{"date":92,"type":41},"2026-03-27",{"date":94,"type":20},"2026-04-01",{"date":96,"type":20},"2026-12-30",{"name":98,"class":48},"Shanghai Pulmonary Hospital, Shanghai, China",3,{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":4,"eligibilityCriteria":106,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":107,"enrollmentInfo":108,"targetDuration":4,"studyType":21,"phases":110,"briefSummary":111,"conditions":112,"keywords":115,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":125,"locationsCount":49},"100594528","serratus-posterior-superior-intekcostal-plane-block-vs-serratus-anterior-plane-block-for-postoperative-analgesia-in-vats-a-randomized-trial-100594528","NCT07020624","Serratus Posterior Superior Intekcostal Plane Block vs Serratus Anterior Plane Block for Postoperative Analgesia in VATS: A Randomized Trial\"","Comparison of the Analgesic Effects of Serratus Posterior Superior Intercostal Plane Block (SPSIPB) and Serratus Anterior Plane Block (SAPB) on Postoperative Analgesia in Video-Assisted Thoracoscopic Surgery (VATS)","Inclusion Criteria:\n\n* BMI \\\u003C 35 kg\u002Fm² Patients with ASA scores I, II, III\n\nExclusion Criteria:\n\n* Patients who do not want to be included in the study Psychiatric and neurological disease with blurred consciousness Patients with ASA \\> 3 BMI \\> 35 kg\u002Fm² Abnormality in coagulation parameters History of allergy to local anesthetic drugs Infection at the injection site Patients whose surgical procedure time exceeds 150 minutes","80 Years",{"count":109,"type":20},50,[23],"Thoracotomy is known as one of the most painful surgical procedures, with up to 65% of patients developing chronic post-thoracotomy pain syndrome (PTPS), and approximately 10% experiencing pain that significantly impacts quality of life. Video-assisted thoracoscopic surgery (VATS) has become increasingly common over the past decade and offers reduced postoperative pain, morbidity, and length of hospital stay compared to open thoracotomy. However, VATS can still cause moderate to severe postoperative pain and a high risk of chronic pain. Optimizing analgesia after VATS remains critical. With advances in ultrasound technology, several regional anesthesia techniques such as serratus anterior plane block (SAPB), erector spinae plane block (ESPB), and thoracic epidural analgesia (TEA) have shown comparable efficacy. In 2023, Tulgar et al. described the serratus posterior superior intercostal plane block (SPSIPB), which demonstrated dermatomal coverage from C3 to T10. This randomized controlled trial aims to compare the analgesic efficacy of SPSIPB and SAPB in patients undergoing VATS procedures.",[113,114],"Video Assisted Thoracoscopic Surgery","Postoperative Analgesia",[116,117,118],"serratus posterior superior intercostal plane block","Video-assisted thoracoscopic surgery","serratus anterior plane block","2025-06-10",{"date":121,"type":41},"2025-06-13",{"date":123,"type":20},"2025-07-01",{"date":71,"type":20},{"name":126,"class":48},"Samsun University",{"id":128,"slug":129,"hasResults":11,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":4,"eligibilityCriteria":133,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":107,"enrollmentInfo":134,"targetDuration":4,"studyType":21,"phases":135,"briefSummary":136,"conditions":137,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":49},"100593794","rhomboid-intercostal-and-subserratus-plane-block-vs-erector-spinae-plane-block-in-video-assisted-thoracoscopic-surgery-100593794","NCT07011069","Rhomboid Intercostal and Subserratus Plane Block vs Erector Spinae Plane Block in Video-Assisted Thoracoscopic Surgery","Comparison of the Efficacy of Rhomboid Intercostal and Subserratus Plane Block (RISS) Versus Erector Spinae Plane (ESP) Blocks in Video-Assisted Thoracoscopic Surgery (VATS) for Postoperative Pain Management and Respiratory Function","Inclusion Criteria:\n\n* Patients who will undergo VATS\n* Who agrees to participate\n* American Society of Anesthesiologists (ASA) physical status I, II, and III\n* Elective surgery\n* Age between 18 and 80 years\n\nExclusion Criteria:\n\n* Local anesthetic allergy\n* Who disagrees to participate\n* ASA physical status IV and V\n* Emergency surgery\n* Hemorrhagic disease\n* Thoracic vertebrae deformity\n* Thoracic vertebrae surgery",{"count":19,"type":20},[23],"To compare the rhomboid intercostal subserratus plane block with the erector spinae plane block regarding their analgesic efficacy and effects on respiratory function for patients undergoing video-assisted thoracoscopic surgery.",[113,138,139,140],"Regional Block for Pain Control","Regional Blocks","Pulmonary Functions","2025-06-04",{"date":143,"type":41},"2025-06-08",{"date":145,"type":41},"2024-11-15",{"date":147,"type":20},"2026-12-31",{"name":149,"class":150},"Bursa City Hospital","OTHER_GOV",{"id":152,"slug":153,"hasResults":11,"nctId":154,"briefTitle":155,"officialTitle":156,"acronym":4,"eligibilityCriteria":157,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":158,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":160,"conditions":161,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":165,"lastUpdatePostDateStruct":166,"startDateStruct":168,"completionDateStruct":170,"leadSponsor":172,"locationsCount":4},"100580330","trending-ability-of-end-tidal-capnography-to-reflect-arterial-carbon-dioxide-changes-in-one-lung-ventilation-100580330","NCT06835894","Trending Ability of End-Tidal Capnography to Reflect Arterial Carbon Dioxide Changes in One-Lung Ventilation","Do End-Tidal Capnography Trends Reflect Changes in Arterial Carbon Dioxide Partial Pressure During One-Lung Ventilation for Thoracoscopic Surgery? A Prospective Observational Study","Inclusion Criteria:\n\n* Patients undergoing thoracoscopic lung surgery with one-lung ventilation\n* Patients requiring invasive arterial blood pressure monitoring\n\nExclusion Criteria:\n\n* Chronic obstructive pulmonary disease (COPD)\n* Pulmonary hypertension\n* Systemic infection",{"count":159,"type":20},115,"In this study, we want to find out if measuring carbon dioxide from a patient's breath (end-tidal CO₂ or ETCO₂) can reliably reflect changes in blood carbon dioxide levels (arterial CO₂ or PaCO₂) during lung surgery. Instead of just looking at individual values, we are specifically investigating whether ETCO₂ and PaCO₂ rise and fall in the same direction over time.\n\nDuring lung surgery, patients often need \"one-lung ventilation,\" where only one lung is used for breathing while the other is deflated to help the surgeon. This can cause carbon dioxide levels in the blood to change, which are typically monitored by taking blood samples. If ETCO₂ trends closely follow PaCO₂ trends, doctors may not need to take as many blood samples.\n\nPatients in this study will already have a small tube in an artery for monitoring blood pressure. Whenever a blood test is taken, we will compare the blood CO₂ level with the ETCO₂ reading at that moment. We will also track heart rate, blood pressure, and body temperature.\n\nBy comparing these measurements, we hope to learn whether ETCO₂ reliably follows the same trends as PaCO₂, making it a useful tool for monitoring carbon dioxide levels in lung surgery with fewer blood tests.",[28,162,163,164],"One-Lung Ventilation","Capnography","Blood Gas Analysis","2025-02-14",{"date":167,"type":41},"2025-02-19",{"date":169,"type":20},"2025-04-01",{"date":171,"type":20},"2025-07-10",{"name":173,"class":48},"Koç University",{"id":175,"slug":176,"hasResults":11,"nctId":177,"briefTitle":178,"officialTitle":179,"acronym":4,"eligibilityCriteria":180,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":181,"enrollmentInfo":182,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":184,"conditions":185,"keywords":188,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":191,"lastUpdatePostDateStruct":192,"startDateStruct":194,"completionDateStruct":196,"leadSponsor":198,"locationsCount":49},"100556962","effect-of-chest-tube-withdrawal-on-patients-anxiety-levels-after-thoracic-surgery-100556962","NCT06531928","Effect of Chest Tube Withdrawal on Patients' Anxiety Levels After Thoracic Surgery","The Effect of Chest Tube Withdrawal on Patients' Anxiety Levels After Video-Assisted Thoracoscopic Surgery","Inclusion Criteria:\n\n* The ages of 18-65\n* BMI between 18-35 kg\u002Fm2\n* Who have undergone VATS\n* Who have a single chest tube inserted during surgery\n* who have undergone resection with VATS (wedge resection, segmentectomy, lobectomy)\n\nExclusion Criteria:\n\n* Who have undergone surgery under emergency conditions,\n* Who have undergone thoracotomy, decortication, pleural biopsy,\n* Who constantly use anti-inflammatory or analgesic drugs,\n* Patients with preoperative chronic pain,\n* Who have undergone thoracic surgery before,\n* Patients with a history of chest tube insertion and for any reason after surgery (prolonged air leakage),\n* Patients whose chest tube has not been removed for more than 7 days,\n* Who have undergone pleurodesis\n* Patients with psychiatric diagnoses or who use psychiatric drugs\n* Who are illiterate will be excluded from the study.","65 Years",{"count":183,"type":20},60,"Since the removal of the chest tube is a painful procedure, it can cause serious anxiety in patients. Patients state that chest tube removal is among the bad memories they experience. The source of the anxiety may be related to fear and anxiety about the pain caused by the upcoming chest tube removal procedure, or it may be the words they have heard from other patients who have had this experience before. There are a limited number of studies in the literature on anxiety that may occur in patients due to chest tube withdrawal. In addition, studies in the literature did not focus on whether there was a difference between pre-procedure and post-procedure anxiety levels. In this study, it was aimed to investigate the anxiety levels before and after the procedure and the pain levels felt in the patients due to the procedure due to chest tube withdrawal in patients who underwent VATS. In addition, it aimed to investigate whether there is any correlation between pre-procedure anxiety and pain experienced during the procedure. If a correlation is detected, the importance of pre-procedural anxiety management will be better understood, the necessity of interventions such as psychological and pharmacological treatment for anxiety will come to the fore, and new research on this subject will be needed.",[186,187],"Chest Tube Withdrawal","Video-assisted Thoracoscopic Surgery",[189,64,190,117,33],"Chest tube withdrawal","Anxiety","2025-01-08",{"date":193,"type":41},"2025-01-09",{"date":195,"type":41},"2024-08-15",{"date":197,"type":20},"2025-07-30",{"name":199,"class":150},"Ankara Ataturk Sanatorium Training and Research Hospital",{"id":201,"slug":202,"hasResults":11,"nctId":203,"briefTitle":204,"officialTitle":205,"acronym":4,"eligibilityCriteria":206,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":107,"enrollmentInfo":207,"targetDuration":4,"studyType":21,"phases":209,"briefSummary":210,"conditions":211,"keywords":215,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":218,"lastUpdatePostDateStruct":219,"startDateStruct":221,"completionDateStruct":222,"leadSponsor":224,"locationsCount":49},"100548877","tpvb-or-spsipb-in-pain-management-after-vats-100548877","NCT06426706","TPVB or SPSIPB in Pain Management After VATS","Paravertebral Block or Serratus Posterior Superior Intercostal Plane Block in Pain Management After Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Patients between the age of 18-80 undergoing video-assisted thoracoscopic surgery\n\nExclusion Criteria:\n\n* Allergy to local anaesthetics Chronic opioid use history Patients with psychiatric disorders Patients who are not open to communication Patients with chronic organ failure Patients that do not give consent Patients that need emergency surgery within the first 24 hours of the initial surgery",{"count":208,"type":20},44,[23],"The goal of this clinical trial is to compare the analgesic efficacy of thoracal paravertebral block (TPVB) and serratus posterior superior intercostal plane block (SPSIPB) in patients undergoing video-assisted thoracoscopic surgery (VATS). The main questions it aims to answer are:\n\nHow will the total perioperative opioid consumption of the patients receiving two different blocks change? How will TPVB and SPSIPB effect the patients' numeric rating scores for pain in the postoperative 24-hour period? How will TPVB and SPSIPB effect the incidence of opioid related side effects?\n\nParticipants will be divided in two groups:\n\nTPVB group will receive a TPVB before the surgery. SPSIPB group will receive a SPSIPB nerve block before the surgery. Researchers will compare the results between the groups to see the postoperative effects concerning opioid consumption as well as the pain scores, respiratory parameters and opioid associated side effects.\n\nThe hypothesis of this study is that participants receiving SPSIPB for VATS will have a less total opioid consumption 24 hours postoperatively.",[187,212,213,214],"Paravertebral Block","Serratus Posterior Superior Intercostal Plane Block","Regional Anesthesia Morbidity",[216,217,116],"video-assisted thoracoscopic surgery","paravertebral block","2025-01-02",{"date":220,"type":41},"2025-01-03",{"date":220,"type":20},{"date":223,"type":20},"2025-03-15",{"name":173,"class":48}]