[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"viral-bronchiolitis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:viral-bronchiolitis":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":18,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100652970","internal-jugular-vein-respiratory-variability-as-a-marker-of-disease-severity-in-infant-bronchiolitis-100652970",false,"NCT07778225","Internal Jugular Vein Respiratory Variability as a Marker of Disease Severity in Infant Bronchiolitis","Respiratory Variation of Internal Jugular Vein Diameter as a Novel Ultrasonographic Marker of Disease Severity in Infants With Acute Bronchiolitis: A Prospective Observational Cohort Study","IJV-BRONCH","Inclusion Criteria:\n\n* Infants aged 1-23 months\n* Clinical diagnosis of acute bronchiolitis per AAP (2014) criteria (first wheezing episode following an upper respiratory infection prodrome, with tachypnea, retractions, and\u002For crackles)\n* Written informed consent obtained from parent\u002Flegal guardian\n* Evaluable within the first 6 hours of emergency department presentation\n\nExclusion Criteria:\n\n* Underlying congenital heart disease\n* Chronic lung disease (bronchopulmonary dysplasia, cystic fibrosis)\n* Prior history of recurrent wheezing\u002Fsuspected asthma\n* Anatomical abnormality of the neck or prior history of central venous catheterization or jugular vein thrombosis\n* Hemodynamic instability\u002Fshock\n* Immediate need for intubation\u002Fmechanical ventilation precluding ultrasound assessment\n* Parent\u002Flegal guardian declines consent","ALL","1 Month","23 Months",{"count":21,"type":22},120,"ESTIMATED","OBSERVATIONAL","This prospective observational cohort study evaluates whether respiratory-cycle variation in internal jugular vein (IJV) diameter, measured by point-of-care ultrasound, correlates with clinical disease severity in infants 1-23 months of age presenting with acute bronchiolitis. Using a standardized M-mode protocol, the IJV Variability Index (\\[IJVmax-IJVmin\\]\u002FIJVmax x 100) will be calculated and compared with the Wang Bronchiolitis Severity Score, four additional validated clinical severity instruments (Modified Tal Score, Respiratory Distress Assessment Instrument, Kristjansson Respiratory Score, Respiratory Assessment Change Score), oxygen saturation, respiratory rate, need for high-flow nasal cannula or supplemental oxygen, pediatric intensive care unit admission, and length of hospital stay. Concurrent lung and diaphragm point-of-care ultrasound will be performed to build a multimodal ultrasound severity model. No intervention is assigned; all ultrasound assessments are performed in addition to standard clinical care and do not alter treatment decisions.",[26,27,28],"Acute Bronchiolitis","Viral Bronchiolitis","Respiratory Syncytial Virus Infections",[30,31,32,33,34],"bronchiolitis","point-of-care ultrasound","internal jugular vein","lung ultrasound","pediatric emergency medicine","NOT_YET_RECRUITING","2026-08-20",{"date":38,"type":39},"2026-08-21","ACTUAL",{"date":41,"type":22},"2026-09-01",{"date":43,"type":22},"2027-08-31",{"name":45,"class":46},"Eskisehir Osmangazi University","OTHER"]