[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"wide-neck-aneurysm\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:wide-neck-aneurysm":98},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,54],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100651102","early-complications-after-flow-diverter-versus-stent-assisted-coiling-for-unruptured-wide-neck-intracranial-bifurcation-aneurysms-100651102",false,"NCT07754188","Early Complications After Flow Diverter Versus Stent-Assisted Coiling for Unruptured Wide-Neck Intracranial Bifurcation Aneurysms","Early Complications After Flow Diverter Versus Stent-Assisted Coiling for Unruptured Wide-Neck Intracranial Bifurcation Aneurysms: A Prospective Real-World Cohort Study","FD-SAC BAS","Inclusion Criteria:\n\n* Voluntarily provides written informed consent.\n* Aged 18 to 75 years.\n* Diagnosed by CTA, MRA, or DSA as having an unruptured, bifurcation, saccular, wide-neck intracranial aneurysm.\n* Able to understand the purpose of the study.\n\nExclusion Criteria:\n\n* Patients with two or more multiple aneurysms, all of which require treatment within 1 year.\n* Patients with other cerebrovascular diseases such as arteriovenous malformation or moyamoya disease.\n* Patients with ruptured aneurysms or narrow-neck aneurysms.\n* Patients who experienced stroke, including cerebral hemorrhage or cerebral infarction, within the past 1 month.\n* Patients with poor clinical condition, defined as modified Rankin Scale score ≥3.\n* Patients who have already planned to undergo surgical or interventional treatment within 3 months.\n* Patients considered by the investigator to be unsuitable for endovascular treatment, such as those with no suitable vascular access, excessively tortuous vessels, or difficulty in stent delivery.\n* Patients unsuitable for anesthesia or endovascular treatment, including those with major heart, lung, liver, spleen, or kidney disease, brain tumor, severe active infection, disseminated intravascular coagulation, or a history of severe psychiatric disorder.\n* Patients unable to receive antiplatelet or anticoagulant therapy.\n* Patients with a previous or possible severe reaction to contrast agents that would prevent completion of pre-treatment medication or treatment.\n* Patients with a known history of allergy to cobalt-chromium or nickel-titanium alloy materials.\n* Patients who participated in another drug or medical device clinical trial before enrollment and have not reached the time point of the primary endpoint.\n* Pregnant or lactating women.\n* Patients with life expectancy less than 12 months.\n* Patients judged by the investigator to have poor compliance and inability to complete the study as required","ALL","18 Years","75 Years",{"count":21,"type":22},274,"ESTIMATED","30 Days","OBSERVATIONAL","This prospective real-world cohort study aims to compare early postoperative complications between flow diverter treatment and stent-assisted coiling in patients with unruptured wide-neck intracranial bifurcation aneurysms. A total of 274 patients from three centers in China will be enrolled and assigned to the flow diverter group or the stent-assisted coiling group according to the treatment received in routine clinical practice. The primary outcome is a composite of any stroke or all-cause death within 30 days after the procedure. The study will also collect demographic, clinical, laboratory, imaging, aneurysm morphological, procedural, and follow-up data to evaluate the safety of these two endovascular treatment strategies in a real-world setting.",[27,28,29],"Unruptured Intracranial Aneurysm","Intracranial Bifurcation Aneurysm","Wide-Neck Aneurysm",[31,32,33,34,35,36,37,38,39,40],"Intracranial bifurcation aneurysm","Wide-neck aneurysm","Flow diverter","Stent-assisted coiling","Endovascular treatment","Early complications","Stroke","All-cause mortality","Real-world study","Prospective cohort","RECRUITING","2026-08-04",{"date":44,"type":45},"2026-08-10","ACTUAL",{"date":47,"type":45},"2026-03-19",{"date":49,"type":22},"2028-03-19",{"name":51,"class":52},"Nanfang Hospital, Southern Medical University","OTHER",3,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":62,"targetDuration":64,"studyType":24,"phases":4,"briefSummary":65,"conditions":66,"keywords":76,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":97},"100629458","targeting-real-world-usage-in-stroke-treatment-100629458","NCT07474935","Targeting Real World Usage In Stroke Treatment","TRUST Registry - Targeting Real World Usage In Stroke Treatment A WallabyPhenox Hemorrhagic Stroke Registry","TRUST","Inclusion Criteria:\n\n* Subject treated or intended to be treated with at least one target registry device during the procedure (i.e., at least one attempt of introduction into the vasculature of the subject),\n* Non-opposition to data collection or informed consent provided by the subject or legal representative as per country-specific legislation.\n\nExclusion Criteria:\n\n* Participation in an interventional study modifying standard care management for all relevant indications,",{"count":63,"type":22},5000,"5 Years","TRUST Registry is an observational, prospective, long-term, post-market surveillance registry of subjects treated with WallabyPhenox flow modulation devices, stent systems, bifurcation aneurysm implants including their HPC variants (Hydrophilic Polymer Coating) where applicable as well as coil systems, and other adjunctive medical devices.\n\nThe overarching purpose of this registry is to carry out a proactive gathering, recording, and analysis of data on the safety, performance and usability of the devices as applied within the routine practice of the participating registry sites.",[67,68,69,70,71,72,73,74,75],"Saccular and Fusiform Aneurysms","Pseudoaneurysm","Vascular Dissection","Perforation","Bifurcation Aneurysms","Stenosis","Neurovascular Abnormalties","Wide-neck Aneurysm","Intracranial Aneurysms",[77,78,79,80,81,82,83,84,85,86],"TRUST Registry","Registry study","Flow Diverter","WallabyPhenox","p48 MW (HPC)","p64","Avenir Coil","p64 MW (HPC)","pEGASUS HPC","pCONUS 2 (HPC)","2026-03-11",{"date":89,"type":45},"2026-03-16",{"date":91,"type":45},"2026-01-29",{"date":93,"type":22},"2041-01",{"name":95,"class":96},"Phenox GmbH","INDUSTRY",13,"Wide Neck Aneurysm"]