[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"wound-complications\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:wound-complications":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,53],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":48,"leadSponsor":50,"locationsCount":4},"100647280","closed-incision-npwt-to-prevent-wound-complications-post-ecmo-100647280",false,"NCT07709546","Closed Incision NPWT to Prevent Wound Complications Post-ECMO","The Prophylactic Effect of Closed Incision Negative Pressure Therapy on Vascular Entry Site Complications Following ECMO Decannulation","PREVENT-ECMO","Inclusion Criteria:\n\n* Patient is aged 18 years or older\n* Is currently receiving ECMO therapy and is eligible for weaning from the device\n* The patient must have at least one cannula inserted at the groin site\n* (Proxy) informed consent\n\nExclusion Criteria:\n\n* Duration ECMO run \\\u003C 24 hours\n* Expected death within 24 hours after decannulation\n* Extracorporeal carbon dioxide removal (ECCO2R) using low blood flow devices or pumpless devices (i.e., MINILUNG ®, PrismaLung+)\n* Wound closure is not possible after decannulation.\n* Presence of drain in the wound site\n* Participants who are not proficient in Dutch or English, or whose legal representative is not proficient, if applicable","ALL","18 Years",{"count":20,"type":21},144,"ESTIMATED","INTERVENTIONAL",[24],"NA","Patients undergoing extracorporeal membrane oxygenation (ECMO) are at increased risk of wound complications at the vascular access site after decannulation. These complications may delay recovery and increase healthcare burden. Closed incision negative pressure wound therapy (NPWT) may improve wound healing by reducing fluid accumulation and supporting the incision. This study evaluates whether prophylactic NPWT reduces wound complications compared to standard wound care following ECMO decannulation.",[27,28,29],"ExtraCorporeal Membrane Oxygenation (ECMO)","Wound Complications","Surgical Site Infection (SSI)",[31,32,33,34,35,36,37,28,38,39,40,41],"ECMO","Extracorporeal Membrane Oxygenation","Negative Pressure Wound Therapy","NPWT","Prevena","Closed Incision Negative Pressure Therapy","ciNPT","Surgical Site Infection","CRWC","Groin wound","Vascular access site","NOT_YET_RECRUITING","2026-07-13",{"date":45,"type":46},"2026-07-16","ACTUAL",{"date":43,"type":21},{"date":49,"type":21},"2029-03-18",{"name":51,"class":52},"St. Antonius Hospital","OTHER",{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":22,"phases":63,"briefSummary":64,"conditions":65,"keywords":73,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":87},"100593147","clinical-impact-of-surgical-wound-morbidity-according-to-the-type-of-saphenous-vein-harvesting-technique-endoscopic-vs-open-in-patients-undergoing-myocardial-revascularization-surgery-100593147","NCT07002658","Clinical Impact of Surgical Wound Morbidity According to the Type of Saphenous Vein Harvesting Technique (Endoscopic vs. Open) in Patients Undergoing Myocardial Revascularization Surgery","Endoscopic Saphenous Vein Harvesting Versus Conventional Open Harvesting in Patients Undergoing Coronary Artery Bypass Grafting, Either Alone or in Combination With Another Cardiac Surgical Procedure, in Terms of the Clinical Impact of Surgical Wound Morbidity","EndOSiC","Inclusion Criteria:\n\n* Patients undergoing coronary artery bypass grafting (CABG), alone or in combination with other surgery (valve or arrhythmia surgery), with or without cardiopulmonary bypass (CPB), in which preoperative evaluation includes the plan to use a short saphenous vein segment (alone or in addition to arterial conduits).\n* Availability of a surgeon or cardiac surgery resident trained in endoscopic harvesting in the operating room.\n* Patients undergoing myocardial revascularization surgeries with or without extracorporeal circulation.\n* Patients undergoing concomitant cardiac valve replacement surgery, atrial fibrillation surgery, and others, in addition to CABG\n\nExclusion Criteria:\n\n* Emergent surgery or procedures performed during cardiorespiratory arrest\n* Myocardial revascularization with arterial grafts only\n* Presence of varicose veins\n* History of infrainguinal vascular surgery\n* Presence of ulcers and\u002For active infection in the lower limbs\n* Previous stroke with neurological sequelae in the legs\n* History of deep vein thrombosis in the legs\n* Pregnancy\n* Age under 18 years\n* Lack of signed informed consent",{"count":62,"type":21},356,[24],"The goal of this clinical trial is to compare two different techniques: endoscopic saphenous vein harvesting versus conventional open harvesting in patients undergoing coronary artery bypass grafting, either alone or in combination with another cardiac surgical procedure (valve surgery or arrhythmia surgery). The main questions the trial aims to answer are:\n\nDoes the endoscopic technique reduce surgical wound morbidity in terms of shorter hospital stays? Does endoscopic saphenous harvesting reduce the use of antibiotics for saphenectomy wound infections? Does the endoscopic technique reduce need for wound dressings due to necrosis and\u002For wound infection, and reduce need for analgesic treatment for wound pain? This prospective, randomized study will be conducted in the Cardiovascular Surgery Service at Hospital Clínico San Carlos.\n\nParticipants will be randomly assigned to a different saphenectomy technique. All patients will be assessed for saphenectomy wound complications upon discharge, and by phone call at 7 days, 1 month, and 3 months following the intervention.",[66,67,68,28,69,70,71,72],"CABG-patients","Saphenectomy","Endoscopic Surgery","Antibiotic Use","Cardiac Surgery","Off Pump Coronary Artery Bypass Graft","Coronary Artery Bypass Graft With or Without ECC",[74,75,76,77],"endoscopic vein harvesting","CABG surgery","open vein harvesting","wound morbidity","2025-06-03",{"date":80,"type":46},"2025-06-06",{"date":82,"type":21},"2025-07-01",{"date":84,"type":21},"2026-08-01",{"name":86,"class":52},"Hospital San Carlos, Madrid",1]