[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"young-adults\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:young-adults":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,15,0,[8,46,73,101,128,155,178,212,246,277,306,334,361,395,422],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100652094","evaluating-food-messaging-campaigns-for-young-adults-100652094",false,"NCT07768488","Evaluating Food Messaging Campaigns for Young Adults","Evaluating a Counter-marketing Campaign to Improve Diet Quality Among Young Adults","Inclusion Criteria:\n\n* 18-29 years old\n* Reside in the US\n* Speak English\n* Use Instagram 3-4 times per week or more\n* Consume sugary drinks 5-6 times per week or more and consume sweet and salty snacks 5-6 times per week or more\n\nExclusion Criteria:\n\n* Younger than 18 years or older than 29 years\n* Do not reside in the US\n* Do not speak English\n* Use Instagram less than 3-4 times per week\n* Consume sugary drinks less than 5-6 times per week or consume sweet and salty snacks less than 5-6 times per week",true,"ALL","18 Years","29 Years",{"count":21,"type":22},750,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to determine whether online social media campaigns improve diet quality among young adults. Young adults will be exposed to one of three social media campaigns.",[28,29,30,31,32,33],"Social Media","Diet Quality","Diet Intervention","Communication","Young Adults","Nutrition","NOT_YET_RECRUITING","2026-08-14",{"date":37,"type":38},"2026-08-17","ACTUAL",{"date":40,"type":22},"2027-09",{"date":42,"type":22},"2029-04",{"name":44,"class":45},"Stanford University","OTHER",{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":16,"sex":54,"minAge":18,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100641580","effects-of-passive-recovery-methods-after-high-intensity-cycling-exercise-100641580","NCT07652398","Effects of Passive Recovery Methods After High-Intensity Cycling Exercise","Acute Effects of Five Passive Recovery Interventions Following High-Intensity Cycling Exercise: A Randomized Five-Period Crossover Trial","RECOVER-CYCLE","Inclusion Criteria:\n\n* Healthy adult volunteers aged 18-30 years\n* Able to perform high-intensity cycling exercise\n* No musculoskeletal injury within the last six months\n* No known cardiovascular, neurological, or metabolic disease\n* Not using medication that may affect exercise performance, pain perception, or recovery\n* Willing to attend all five study sessions\n* Willing to receive all five passive recovery interventions\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Presence of acute or chronic musculoskeletal injury\n* History of cardiovascular, neurological, respiratory, or metabolic disease\n* Contraindication to high-intensity exercise\n* Contraindication to compression therapy, vacuum therapy, kinesiology taping, passive rest, or classical massage\n* Skin allergy, open wound, dermatological disease, or sensitivity to kinesiology tape\n* Use of analgesic, anti-inflammatory, muscle relaxant, or performance-enhancing medication during the study period\n* Participation in another exercise or recovery intervention study during the study period\n* Failure to attend all study sessions or comply with study procedures","FEMALE","30 Years",{"count":57,"type":22},12,[25],"This randomized crossover trial will investigate the acute effects of five passive recovery interventions following a standardized high-intensity cycling exercise protocol. Participants will complete the standardized high-intensity cycling exercise protocol during five separate study sessions. Immediately after each exercise session, participants will receive one of five recovery interventions: compression therapy, vacuum therapy, kinesiology taping, passive rest, or classical massage. The order of the interventions will be randomized according to a balanced crossover sequence. Each participant will experience all five recovery interventions during the study period. Outcomes related to post-exercise recovery will be assessed across intervention periods.",[61,32],"Young Adult Health","RECRUITING","2026-08-07",{"date":65,"type":38},"2026-08-11",{"date":67,"type":38},"2026-06-22",{"date":69,"type":22},"2026-08-21",{"name":71,"class":45},"Pamukkale University",1,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":23,"phases":83,"briefSummary":84,"conditions":85,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":72},"100648858","digital-psychoeducational-intervention-for-young-adults-with-fertility-related-distress-following-cancer-diagnosis-100648858","NCT07729696","Digital Psychoeducational Intervention for Young Adults With Fertility Related Distress Following Cancer Diagnosis","Effectiveness of a Digital Psychoeducational Intervention for Young Adults With Fertility Related Distress Following Cancer Diagnosis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosed with cancer.\n* Self-report fertility-related distress.\n* Aged 18 to 40 years old.\n* Able to speak Bahasa (the national language of Indonesia).\n* Have a performance status ECOG score of 0-2.\n\nExclusion Criteria:\n\n* Have a severe medical condition which impacts their level of consciousness.\n* Diagnosed with a major psychiatric comorbidity.\n* Unable to fill out the study questionnaires.\n* Unable to decide to participate due to cognitive impairment, decreasing consciousness level, or difficulty verbalizing their wishes.","40 Years",{"count":82,"type":22},38,[25],"The goal of this randomized controlled trial is to evaluate the effectiveness of a digital psychoeducational intervention for young adults experiencing fertility-related distress following a cancer diagnosis. It will also assess how the intervention supports the development of effective coping strategies and social support networks. The main questions it aims to answer are: Does the digital psychoeducational intervention reduce anxiety and depression severity compared with usual care? Does the digital psychoeducational intervention increase patients' self-efficacy, social support, and coping compared with usual care? Does the digital psychoeducational intervention increase patients' quality of life compared with usual care? Researchers will compare the digital psychoeducational intervention to usual care (standard treatment) to see if the intervention effectively manages psychological problems and improves quality of life. Participants will:Be randomly assigned to either the experimental group or the control group. Attend an initial face-to-face introductory session, followed by four digital psychoeducational modules delivered via a mobile phone application (if assigned to the experimental group). Engage with module content including an e-booklet, video, and quizzes, with a new module opening every two days. Receive standard treatment from healthcare providers, and later receive the psychoeducational materials at the end of the data collection period (if assigned to the control group). Complete a series of validated questionnaires measuring depression, anxiety, coping, self-efficacy, social support, and quality of life at four different time points throughout the study.",[86,87,88,32,89,90,91],"Neoplasm","Cancer","Psychoeducational Intervention","Fertility Outcomes","Psychological Distress","Anxiety","2026-07-23",{"date":94,"type":38},"2026-07-27",{"date":96,"type":22},"2026-08-24",{"date":98,"type":22},"2026-12-14",{"name":100,"class":45},"Gadjah Mada University",{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":16,"sex":17,"minAge":108,"maxAge":109,"enrollmentInfo":110,"targetDuration":4,"studyType":23,"phases":112,"briefSummary":113,"conditions":114,"keywords":115,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":72},"100648362","effects-of-tool-handling-on-language-processing-100648362","NCT07718698","Effects of Tool Handling on Language Processing","Analysis of the Effect of a Tool-Handling Intervention in a Specific Context on the Linguistic Processing of Healthy Young Adults","Inclusion Criteria:\n\n* Healthy young adults aged between 19 and 24 years;\n* Right-handed individuals.\n\nExclusion Criteria:\n\n* Previous diagnosis of neurological and\u002For psychiatric disorders;\n* History of traumatic brain injury;\n* Use of psychoactive substances or medications that may affect cognitive functioning;\n* Pregnancy or suspected pregnancy.","19 Years","24 Years",{"count":111,"type":22},60,[25],"This randomized controlled trial aims to investigate the effects of a context-specific tool-handling intervention on linguistic processing in healthy young adults. Participants will be allocated into three groups: a dexterous tool-use training group, a dexterous manual training group without tools, and a Control group.\n\nThe dexterous tool-use training group will perform a task-oriented activity involving the use of tweezers to place colored beads into a mandala within a specific functional context. The intervention requires sequential motor planning, force control, precision, and goal-directed tool use. The dexterous manual training group without tools will perform a similar bead-placement activity without tool use, involving direct hand manipulation and lower task complexity. Both intervention groups will participate in synchronous online sessions via Google Meet for 20 minutes per day, five times per week, over a two-week period.\n\nThe Control group will not receive any structured intervention and will instead be instructed to perform one activity of daily living using the non-dominant upper limb once per day during the two-week period.\n\nLinguistic processing will be assessed through a sentence judgment task involving sentences with and without semantic violations, in which participants will classify the sentences as correct or incorrect while electroencephalographic activity (EEG) is recorded. Additionally, sleep quality and manual dexterity will also be evaluated.\n\nThe findings of this study may contribute to understanding the relationship between tool-related motor training and linguistic processing, particularly the interaction between motor and language systems in healthy young adults. Additionally, the study may provide evidence regarding neurophysiological changes associated with context-specific motor interventions.",[32],[116,117,118],"tool","manual dexterity","language","2026-07-15",{"date":121,"type":38},"2026-07-22",{"date":123,"type":22},"2026-07-31",{"date":125,"type":22},"2027-03-31",{"name":127,"class":45},"Federal University of Health Science of Porto Alegre",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":134,"eligibilityCriteria":135,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":136,"enrollmentInfo":137,"targetDuration":4,"studyType":23,"phases":139,"briefSummary":140,"conditions":141,"keywords":142,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":146,"lastUpdatePostDateStruct":147,"startDateStruct":149,"completionDateStruct":151,"leadSponsor":153,"locationsCount":72},"100646156","evaluating-the-yatac-programme-100646156","NCT07692763","Evaluating the YATAC Programme","The Young Adult Taking Action Program: Protocol for a Pilot Randomized Controlled Trial of Cancer Rehabilitation for Young Adults","YATAC","Inclusion Criteria:\n\n* Between 18 and 39 years of age\n* Are currently undergoing or have completed curative-intent cancer treatment within the past five years\n* Can understand and communicate in Danish and provide informed consent independently\n* Have been referred to municipal cancer rehabilitation services in the Municipality of Aarhus\n\nExclusion Criteria:\n\n* Diagnosed with cancer before the age of 18\n* Previously or currently receive rehabilitation","39 Years",{"count":138,"type":22},50,[25],"Young adults aged 18-39 years with cancer often experience physical, psychological, and social challenges that affect their participation in everyday life and their health-related quality of life. Existing cancer rehabilitation services are rarely tailored to the specific needs of this age group. The Young Adults Taking Action (YATAC) programme was developed together with young adults with cancer, healthcare professionals, and researchers to provide age-specific rehabilitation that supports young adults in managing cancer-related challenges and returning to everyday life.\n\nThe aim of this pilot randomized controlled trial is to evaluate the feasibility of conducting a larger trial of the YATAC programme in a municipal rehabilitation setting. The study will examine recruitment, retention, acceptability of randomization, data completeness, assessment burden, and adverse events. In addition, the study will provide preliminary estimates of the programme's effects on health-related quality of life and self-efficacy.\n\nFifty young adults aged 18-39 years who are undergoing or have completed curative-intent treatment will be recruited through municipal cancer rehabilitation services in Aarhus Municipality, Denmark. Participants will be randomly assigned to receive either the 16-week YATAC programme or usual cancer rehabilitation services. The YATAC programme includes an individual needs assessment and goal setting, followed by group-based and individual sessions addressing physical activity, fatigue, sleep and cognitive challenges, mental health, sexuality and relationships, family and friends, nutrition, and education or work. Outcomes will be assessed at baseline and at 4, 6, and 12 months after enrolment.",[87,32],[143,144,145],"Randomised controlled trial","Quality of life","Rehabilitation","2026-07-09",{"date":148,"type":38},"2026-07-10",{"date":150,"type":38},"2026-07-03",{"date":152,"type":22},"2028-12-31",{"name":154,"class":45},"University of Aarhus",{"id":156,"slug":157,"hasResults":11,"nctId":158,"briefTitle":159,"officialTitle":160,"acronym":4,"eligibilityCriteria":161,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":109,"enrollmentInfo":162,"targetDuration":4,"studyType":23,"phases":164,"briefSummary":165,"conditions":166,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":169,"lastUpdatePostDateStruct":170,"startDateStruct":172,"completionDateStruct":174,"leadSponsor":176,"locationsCount":72},"100595889","a-text-messaging-trial-to-test-vaping-health-messages-optimized-to-young-adults-vaping-status-100595889","NCT07038317","A Text Messaging Trial to Test Vaping Health Messages Optimized to Young Adults' Vaping Status","Identifying and Examining the Effects of Source and Presentation on Responses to Electronic Cigarette Public Education Messages in Young Adult Vapers and Non-vapers","Inclusion Criteria:\n\n* 18-24 years old\n* Fluent in English\n* Not currently using tobacco products other than e-cigarettes at the time of enrollment\n* Have a mobile phone to send and receive text messages\n\nExclusion Criteria:\n\n* Age below 18 or above 24\n* Not being fluent in English\n* Currently using tobacco products other than e-cigarettes\n* Not having a mobile phone",{"count":163,"type":22},120,[25],"The goal of this study is to examine if e-cigarette education messages delivered using a source and presentation tailored to one's vaping status influences young adults' vaping behaviors. The main questions it aims to answer are:\n\n1. Does receiving e-cigarette education messages presented using a source (expert or peer) and sidedness (one or two-sided) optimized for the current vaper group influence vaping cessation among young adults who vape daily?\n2. Does receiving e-cigarette education messages presented using a source (expert or peer) and sidedness (one or two-sided) optimized for the non-vaper group influence vaping initiation among young adults who are susceptible to vaping? Participants will be randomly assigned to either the treatment (receiving messages tailored to one's vaping status) or the control (receiving non-tobacco messages) condition and receive SMS three times per week over the course of 6 months. They will complete self-report assessment and show salivary cotinine results for nicotine testing at 4 timepoints.",[167,168,32],"Vaping Behaviors","Message Exposure","2026-06-10",{"date":171,"type":38},"2026-06-12",{"date":173,"type":22},"2026-06-30",{"date":175,"type":22},"2028-01-31",{"name":177,"class":45},"University of Hawaii",{"id":179,"slug":180,"hasResults":11,"nctId":181,"briefTitle":182,"officialTitle":182,"acronym":4,"eligibilityCriteria":183,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":184,"enrollmentInfo":185,"targetDuration":4,"studyType":187,"phases":4,"briefSummary":188,"conditions":189,"keywords":193,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":202,"lastUpdatePostDateStruct":203,"startDateStruct":205,"completionDateStruct":207,"leadSponsor":209,"locationsCount":211},"100594442","young-stroke-service-deep-phenotyping-exploring-recovery-in-young-adult-survivors-of-stroke-100594442","NCT07019493","Young Stroke Service Deep Phenotyping: Exploring Recovery in Young Adult Survivors of Stroke","Inclusion Criteria:\n\n1. Between 18 and 55 years.\n2. Within one month of acute stroke confirmed with standard of care brain imaging or clinical diagnosis or for those for whom recruitment \\\u003C1 month of stroke is not possible they may be recruited to participate within 3-months of stroke\n\nExclusion Criteria:\n\n1. Severe, intercurrent or progressive illness likely to EITHER\n\n   1. Have a prognosis for survival under 24 months; OR\n   2. In the opinion of the investigator will mask the importance to the individual participant data (e.g. severe MS, dementia, etc)\n2. Major psychiatric condition requiring medical intervention","55 Years",{"count":186,"type":22},100,"OBSERVATIONAL","The Investigators are running a small, early-phase research study across several hospitals in Melbourne, Australia. The study will involve up to 100 young adults between the ages of 18 and 55 who have had a stroke. The goal is to test how practical it is to carry out a detailed health assessment process-called \"deep phenotyping\"-with this group.\n\nThis process involves collecting a wide range of information and samples from stroke survivors to better understand each participant's condition. The Investigators will look at how well this approach works in practice, including how easy it is to use, whether it's done consistently, and how acceptable it is to participants.\n\nAt the same time, the Investigators will also explore how different factors-such as biological markers (biomarkers), age, sex, type of stroke, lifestyle, and environment-might be related to stroke recovery. This pilot study will prepare for larger studies in the future.",[190,191,192,32],"Stroke Patients","Stroke","Stroke; Sequelae",[194,195,196,197,198,199,200,201],"recovery","young stroke","ischemic stroke","hemorrhagic stroke","poststroke fatigue","post-stroke cognitive impairment","function","mood","2026-04-16",{"date":204,"type":38},"2026-04-21",{"date":206,"type":38},"2025-07-19",{"date":208,"type":22},"2027-12",{"name":210,"class":45},"The Florey Institute of Neuroscience and Mental Health",2,{"id":213,"slug":214,"hasResults":11,"nctId":215,"briefTitle":216,"officialTitle":217,"acronym":218,"eligibilityCriteria":219,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":220,"enrollmentInfo":221,"targetDuration":4,"studyType":23,"phases":222,"briefSummary":223,"conditions":224,"keywords":227,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":238,"startDateStruct":240,"completionDateStruct":242,"leadSponsor":244,"locationsCount":72},"100607710","a-reinforced-mindfulness-based-intervention-to-reduce-problematic-drinking-among-hispanic-emerging-adults-100607710","NCT07192094","A Reinforced Mindfulness-Based Intervention to Reduce Problematic Drinking Among Hispanic Emerging Adults","A Reinforced Mindfulness-Based Intervention to Reduce Problematic Drinking Among Hispanic Emerging Adults: Feasibility and Acceptability","Mindfulness","Inclusion Criteria:\n\n* self-identified Hispanic,\n* 18-25 years old,\n* engaged in 2 or more occasions of heavy episodic drinking occasions (HED) (4\u002F5 drinks in one sitting for females\u002Fmales) during the previous 30-days\n* actively enrolled FIU student. Exclusion Criteria\n\nParticipants will be flagged for exclusion criteria if they report any of the following:\n\n* Five or more binge drinking episodes (5+ drinks in one sitting) in the past 30 days, which averages more than once per week.\n* Weekly or more frequent use of other substances, including non-prescribed prescription drugs, illegal drugs, inhalants, or synthetic drugs.","25 Years",{"count":163,"type":22},[25],"This study is a trial to evaluate a mindfulness program designed for Hispanic young adults. Participants will be randomly assigned to one of two groups: (1) an in-person, 8-week mindfulness program (one 1.5-hour session per week at FIU's MMC campus), or (2) an assessment-only control group. Regardless of group assignment. Participants will be asked to complete online surveys at baseline, after an 8-week period, and again one month later. They will also be asked to provide a fingerpick blood sample and have their heart rate and blood pressure measured at four timepoints: baseline, 1 month, 2 months, and 3 months after baseline. Participation will involve up to 16 hours over approximately 14 weeks. This includes time for completing baseline assessments, participating in the 8-week intervention (if assigned), and completing post-program and follow-up assessments. There are no serious risks of participating in this study, but some of the questions during the assessments, interview, or the fingerpick may cause you discomfort. The main benefit from participating in this clinical trial is that participants may experience personal benefits from learning mindfulness techniques.",[225,32,226],"MBSR","Heavy Episodic Drinking",[228,229,230,231,232,218,233,234,235,225,236],"Young adults","College Students","Ages 18 - 25","Binge Drinking","Stress","Stress Reduction","HRV","Contingency Management","alcohol misuse","2026-02-24",{"date":239,"type":38},"2026-02-25",{"date":241,"type":38},"2026-01-27",{"date":243,"type":22},"2028-07",{"name":245,"class":45},"Florida International University",{"id":247,"slug":248,"hasResults":11,"nctId":249,"briefTitle":250,"officialTitle":250,"acronym":4,"eligibilityCriteria":251,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":220,"enrollmentInfo":252,"targetDuration":4,"studyType":23,"phases":254,"briefSummary":255,"conditions":256,"keywords":260,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":268,"lastUpdatePostDateStruct":269,"startDateStruct":271,"completionDateStruct":273,"leadSponsor":275,"locationsCount":72},"100552181","theory-based-social-media-intervention-for-non-medical-use-of-prescription-opioids-in-young-adults-100552181","NCT06469749","Theory-based Social Media Intervention for Non-medical Use of Prescription Opioids in Young Adults","Inclusion Criteria:\n\n* aged 18-25 years\n* from the U.S.\n* can read and speak English\n* engage in non-medical use of prescription opioids in the past three months: taking prescription opioids without a doctor's prescription\u002Ftaking more doses of prescription opioids than what a prescription allows\u002Fusing prescription opioid for reasons other than a medical purpose\n* use Instagram three times a week or more in the past three months\n\nExclusion Criteria:\n\n* receiving substance use interventions in the past three months\n* are diagnosed with substance use disorders\n* are not proficient in English",{"count":253,"type":22},70,[25],"Brief Summary\n\nThe purposes of this study are to develop and implement a peer-led intervention program on Instagram for promoting prescription opioid use management and fostering psychosocial skills among young adults who engage in non-medical use of prescription opioids in the United State. The specific aims of the study include:\n\n(1) To implement and test the feasibility of the 12-week peer-led intervention modules on Instagram among young adults who are randomly assigned to either receive the intervention (intervention group) or not receive the intervention (control group)\n\nParticipants who are assigned to the intervention group will be paired with a peer leader and attend to peer-guided interactive modules on Instagram over 12 weeks. They will complete an online survey at 1st week and 12th week, as well as brief evening surveys every two days during the intervention. The control group will not take part in intervention activities but will complete an online survey at 1st week and 12th week.",[32,257,258,259],"Past-3-month Non-medical Use of Prescription Opioids","Without Substance Use Disorders","Social Media Users",[261,32,262,263,264,265,266,267],"opioids","Information-Motivation-Behavioral skills Model","Psychosocial factors","social media","Resilience","Mental health","Peer role model","2026-02-20",{"date":270,"type":38},"2026-02-23",{"date":272,"type":22},"2026-11-01",{"date":274,"type":22},"2029-03-31",{"name":276,"class":45},"University of South Carolina",{"id":278,"slug":279,"hasResults":11,"nctId":280,"briefTitle":281,"officialTitle":282,"acronym":283,"eligibilityCriteria":284,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":285,"targetDuration":4,"studyType":23,"phases":286,"briefSummary":287,"conditions":288,"keywords":291,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":297,"lastUpdatePostDateStruct":298,"startDateStruct":300,"completionDateStruct":302,"leadSponsor":304,"locationsCount":72},"100625106","grow-together-thrive-together-a-feasibility-study-of-a-brief-relationship-intervention-for-emerging-adults-and-their-caregivers-100625106","NCT07418320","Grow Together, Thrive Together: A Feasibility Study of a Brief Relationship Intervention for Emerging Adults and Their Caregivers","Grow Together, Thrive Together (G2T2): A Feasibility Study of a Brief Writing-Based Relationship Intervention for Emerging Adults and Their Caregivers","G2T2","Inclusion Criteria:\n\n* Emerging adults aged 18-25 years and their primary caregiver or parent, enrolled as emerging adult-caregiver dyads\n* Both members of the dyad must independently provide informed consent prior to participation\n* Sufficient English literacy to complete online questionnaires in English\n* Reliable access to the internet via a computer or mobile device\n* Dyad members may live together or separately\n* Participants may continue usual or recommended mental health care (e.g., psychotherapy, pharmacotherapy) during the study\n\nExclusion Criteria:\n\n* Concurrent participation in a structured family-based intervention (e.g., manualized family therapy or family skills programs) during the study period",{"count":111,"type":22},[25],"Background. Emerging adulthood is a period of major change in young people's lives, including increased independence, new responsibilities, and shifting relationships with parents or caregivers. During this time, disagreements between emerging adults and caregivers are common and may become more frequent or emotionally intense. How families manage these disagreements may affect relationship quality and emotional well-being for both emerging adults and caregivers. However, there are few brief, accessible programs designed to support emerging adults and caregivers together during this transition.\n\nGrow Together, Thrive Together (G2T2) is a brief, online, writing-based relationship program designed for emerging adults and their caregivers. The program encourages participants to reflect on disagreements using a neutral, outside-observer perspective, with the goal of helping families approach conflict in healthier ways. G2T2 is designed to be low-intensity, self-directed, and accessible, and can be completed remotely using secure online platforms.\n\nThe purpose of this study is to evaluate the feasibility and acceptability of the G2T2 program and study procedures, rather than to test effectiveness. This feasibility clinical trial will examine whether emerging adult-caregiver dyads can be successfully recruited and retained, whether participants complete the writing sessions as planned, and whether participants find the program acceptable, easy to use, and understandable. The study will also explore whether participants report using the conflict reappraisal strategy outside of the writing sessions and examine changes in relationship and conflict-related outcomes before and after the program to inform future research.\n\nParticipants will take part as emerging adult-caregiver pairs. Each participant will complete an online baseline survey, three brief online writing sessions completed over approximately nine weeks, and a follow-up survey one week after the final session. Each writing session includes brief questions about recent disagreements, a short instructional video, brief questions to check understanding of the strategy, and guided writing exercises focused on reflecting on disagreements and planning how to use the strategy in future interactions. All activities are completed independently and online. Findings from this study will be used to refine the G2T2 program and study procedures and to inform the design of a future, larger randomized controlled trial.",[289,290,32],"Parent Child Relationship","Interpersonal Relations",[292,290,293,294,295,296],"Parent-Child Relations","Family Relations","Primary Prevention","Health Promotion","Emerging Adulthood","2026-02-10",{"date":299,"type":38},"2026-02-18",{"date":301,"type":22},"2026-03-20",{"date":303,"type":22},"2027-05-31",{"name":305,"class":45},"York University",{"id":307,"slug":308,"hasResults":11,"nctId":309,"briefTitle":310,"officialTitle":311,"acronym":312,"eligibilityCriteria":313,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":314,"enrollmentInfo":315,"targetDuration":317,"studyType":187,"phases":4,"briefSummary":318,"conditions":319,"keywords":321,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":326,"lastUpdatePostDateStruct":327,"startDateStruct":329,"completionDateStruct":331,"leadSponsor":332,"locationsCount":4},"100602834","clinical-features-and-long-term-prognosis-in-young-patients-with-acute-myocardial-infarction-100602834","NCT07128667","Clinical Features and Long-Term Prognosis in Young Patients With Acute Myocardial Infarction","A Prospective Cohort Study on Clinical Characteristics, Risk Factors, and Long-Term Outcomes in Young Patients With Acute Myocardial Infarction","AMI-Youth","Inclusion Criteria:\n\n1. Age between 18 and 45 years (inclusive of 18 and 45 years);\n2. Meeting the diagnostic criteria for acute myocardial infarction (including both ST-elevation myocardial infarction and non-ST-elevation myocardial infarction);\n3. Presenting for medical attention within 24 hours of symptom onset;\n4. The subject (or their legal representative) is willing and able to sign the informed consent form (for the prospective follow-up portion);\n5. Life expectancy greater than 1 year.\n\nExclusion Criteria:\n\n* (1) History of prior old myocardial infarction, severe valvular heart disease, or heart failure; (2) Pregnancy or lactation; (3) Mental disorders or other conditions that prevent cooperation with treatment; (4) Concomitant severe infection, inflammatory or immunological biomarker changes unrelated to AMI, trauma, or recent major surgery.","45 Years",{"count":316,"type":22},200,"2 Years","The incidence of acute myocardial infarction (AMI) in young patients is on the rise, placing a heavy health and economic burden on individuals, families, and society. The clinical phenotype and pathophysiological mechanisms of AMI in this population exhibit significant heterogeneity compared to elderly patients, and existing risk assessment tools have limited applicability in this specific group. The core problem this study aims to address is: how to accurately identify specific risk factors in young AMI patients and build an effective risk prediction model to prevent and optimize clinical diagnosis and treatment.\n\nThis study will adopt a prospective cohort design to collect multi-dimensional clinical data from young AMI patients. It will systematically analyze their clinical characteristics, risk factors, and coronary lesion status to comprehensively map the clinical, risk factor, and pathophysiological diversity of young AMI patients. Secondly, it will delve into identifying specific risk factors that influence the onset, progression, and long-term prognosis of young AMI. Thirdly, it will combine machine learning algorithms to develop a risk prediction model for young AMI, performing internal validation in the prospective cohort and external validation in the MIMIC-IV database. Simultaneously, it will explore novel biomarkers associated with disease onset and progression. The key outcomes of this study are to establish a high-quality clinical database of young AMI patients, design a risk prediction model for young AMI based on the study results, and produce high-level academic publications.",[320,32],"ACS (Acute Coronary Syndrome)",[322,323,324,325],"acute myocardial infarction","young adults","prognosis","risk factors","2025-08-14",{"date":328,"type":38},"2025-08-19",{"date":330,"type":22},"2025-09-01",{"date":152,"type":22},{"name":333,"class":45},"China-Japan Friendship Hospital",{"id":335,"slug":336,"hasResults":11,"nctId":337,"briefTitle":338,"officialTitle":338,"acronym":339,"eligibilityCriteria":340,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":136,"enrollmentInfo":341,"targetDuration":4,"studyType":23,"phases":343,"briefSummary":344,"conditions":345,"keywords":349,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":352,"lastUpdatePostDateStruct":353,"startDateStruct":355,"completionDateStruct":357,"leadSponsor":359,"locationsCount":72},"100596769","examining-the-circadian-timing-effects-of-the-hypotensive-response-to-exercise-100596769","NCT07049783","Examining the Circadian Timing Effects of the Hypotensive Response to Exercise","XTIME","Inclusion Criteria:\n\n* 18-39 Years old\n* Resting blood pressure greater than or equal to 120\u002F80 mmHg or less than 140\u002F90 mmHg\n\nExclusion Criteria:\n\n* Diagnosis or history of chronic or autoimmune disease (i.e., cardiovascular, metabolic, renal, endocrine, cancer)\n* Diagnosis or history of sleep disorder (i.e., obstructive sleep apnea, insomnia, restless leg syndrome)\n* Alcohol or drug dependence\n* Elevated risk for sleep disorders\n* Elevated risk for clinical depression\n* Normotensive (blood pressure less than 120\u002F80 mmHg) or stage 2+ hypertension (blood pressure greater than or equal to 140\u002F90 mmHg)\n* Body mass index less than 18.5 or greater than 35 kg\u002Fm2\n* Self-reported use of sleep medications\u002Fsupplements (e.g., melatonin)\n* Self-reported use of medications influencing vascular physiology (e.g., antihypertensive medications, weight loss medications)\n* Highly physically active (greater than or equal to 300 minutes moderate-to-vigorous physical activity per week)\n* Currently pregnant or breastfeeding\n* Current tobacco use (greater than or equal to 1 cigarette in the past month)\n* Nighttime or rotating shift work within the last 3 months\n* Contraindications to aerobic exercise",{"count":342,"type":22},30,[25],"The goal of this study is to learn how exercise timing affects blood pressure in adults with elevated or high blood pressure. Exercise can influence the body's natural 24-hour rhythms, including blood pressure patterns. A single exercise session can lower blood pressure for up to 24 hours, but it is not fully understood how the time-of-day for exercise affects this response. The main question this study aims to answer is:\n\n• When the same participant exercises at different times of day (morning, afternoon, or evening), how does this affect the participant's blood pressure over the next 24 hours?\n\nParticipants will:\n\n* Undergo an in-lab assessment of individual biological rhythm that will indicate the clock-time for an individual's biological night\n* Complete 3 supervised treadmill exercise sessions\n\n  * 1 in the biological morning (biological night + 10 hours)\n  * 1 in the biological afternoon (biological night + 15 hours)\n  * 1 in the biological evening (biological night + 20 hours)\n* Complete a 24-hour blood pressure assessment before and after each exercise session",[32,346,347,348],"Hypertension","Post-Exercise Hypotension","Circadian Rhythm",[228,346,350,351],"Post-exercise hypotension","Circadian rhythm","2025-08-12",{"date":354,"type":38},"2025-08-17",{"date":356,"type":38},"2025-07-22",{"date":358,"type":22},"2026-09",{"name":360,"class":45},"Freda Patterson",{"id":362,"slug":363,"hasResults":11,"nctId":364,"briefTitle":365,"officialTitle":366,"acronym":4,"eligibilityCriteria":367,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":368,"enrollmentInfo":369,"targetDuration":4,"studyType":23,"phases":371,"briefSummary":372,"conditions":373,"keywords":381,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":387,"lastUpdatePostDateStruct":388,"startDateStruct":390,"completionDateStruct":392,"leadSponsor":393,"locationsCount":72},"100602108","the-ipeer2peer-mentorship-program-for-young-adults-with-heart-disease-100602108","NCT07119216","The iPeer2Peer Mentorship Program for Young Adults With Heart Disease","The iPeer2Peer Support Mentorship Program for Young Adult Patients With Heart Disease: A Feasibility Study","Inclusion Criteria:\n\n* Peer Mentor inclusion criteria: (a) heart disease patients, (b) at least three months post-diagnosis, (c) between the ages of 26-35 years old, (d) nominated by a member of their healthcare team as a good candidate to act in the mentor role based on maturity and emotional stability (e.g., good communication skills, positive adaptation and adjustment, strong support network), (e) willingness to commit to virtual peer mentor training, (f) able to speak and read English, and (g) access to a device (e.g., smart phone, tablet, computer) capable of using free WhatsApp software.\n* Peer Mentee inclusion criteria: (a) heart disease patients, (b) between the ages of 18-25 years old, (c) able to speak and read English, and (d) access to a device (e.g., smart phone, tablet, computer) capable of using free WhatsApp software.\n\nHeart disease patients include:\n\n* Patients with any past or present heart failure\n* Patients with cardiomyopathy seen at least 2 times a year\n* Patients who have undergone a Fontan procedure\n* Patients who have undergone a heart transplant\n\nExclusion Criteria:\n\n* Mentor and mentee exclusion criteria include: (a) Significant cognitive impairments as assessed by a qualified healthcare provider (HCP), (b) have a diagnosis of an active psychological disorder (e.g.: Major Depressive Disorder, etc.; determined through chart review by a qualified HCP) likely to influence assessment of health-related quality of life and\u002For interfere with their ability to manage their heart disease care regimen, and (c) are participating in other peer support or self-management interventions.","35 Years",{"count":370,"type":22},80,[25],"Young adults with heart failure, including those who have undergone a heart transplant, experience considerable psychosocial stressors associated with living with a chronic illness, including heightened levels of anxiety and depression, and poor health-related quality of life compared to 'healthy' peers. Psychosocial challenges during young adulthood are especially concerning as this life stage represents a unique transitional period for fostering self-identity, friendships, mastery, and decision-making competencies. As young people with heart failure transition into adult healthcare systems, they take on greater personal responsibility due to their increasing independence and involvement in care decisions, and require more support and resources to live longer, healthier lives. Peer support provided by a person with a similar experience has been found to improve disease self-management and psychosocial health outcomes in pediatric healthcare.\n\nAn established, online mentorship program, iPeer2Peer (iP2P), will be employed through a pilot feasibility waitlist randomized controlled trial with repeated measures across five sites. Sixty mentees will be recruited and randomized into intervention and control groups. Thirty mentees in the intervention group will be matched 1:1 with 20 trained mentors. These pairings will connect over 12 weeks through video calls and text messaging to provide peer support to improve self-management and psychosocial health outcomes.",[374,375,376,377,32,378,379,380],"Heart Failure","Mentorship","Peer Support","Peer Support and Chronic Disease","Cardiomyopathies","Heart Transplant Recipient","Fontan Procedure",[382,383,384,385,386],"heart failure","mentorship","peer support","young adult","heart disease","2025-08-05",{"date":389,"type":38},"2025-08-13",{"date":391,"type":22},"2025-09",{"date":208,"type":22},{"name":394,"class":45},"Samantha Anthony",{"id":396,"slug":397,"hasResults":11,"nctId":398,"briefTitle":399,"officialTitle":400,"acronym":4,"eligibilityCriteria":401,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":402,"enrollmentInfo":403,"targetDuration":4,"studyType":23,"phases":404,"briefSummary":405,"conditions":406,"keywords":407,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":413,"lastUpdatePostDateStruct":414,"startDateStruct":416,"completionDateStruct":418,"leadSponsor":420,"locationsCount":72},"100593678","cortical-excitability-and-typing-performance-after-action-observation-and-motor-execution-100593678","NCT07009561","Cortical Excitability and Typing Performance After Action Observation and Motor Execution","Comparison of Cortical Excitability and Typing Performance Across Action Observation, Motor Execution, and Control Conditions","Inclusion Criteria:\n\n* Age between 18 and 26 years\n* Healthy university students with no known neurological, psychiatric, or musculoskeletal conditions\n* Intact motor functioning of the upper limbs\n* Basic typing proficiency using a 10-finger typing method\n* Ability to understand study procedures and provide informed consent\n\nExclusion Criteria:\n\n* Typing speed less than 16 words per minute\n* Use of hunt-and-peck or single-finger typing style\n* History of seizures or epilepsy\n* Current use of neuroactive medications\n* Presence of metallic implants in the head or upper body\n* Any contraindications to Transcranial Magnetic Stimulation (TMS)\n* Left-handed individuals using non-standard typing techniques (unless provided with adapted materials)","26 Years",{"count":111,"type":22},[25],"Goal:\n\nThis study will aim to investigate the effects of different motor stimulation strategies-motor execution (ME) and action observation (AO)-on cortical excitability and typing performance in healthy individuals.\n\nRecruitment:\n\nA total of 60 healthy university students will be recruited and randomly assigned into three groups:\n\nMotor Execution group (n=20) Action Observation group (n=20) Control group (n=20)\n\nEvaluation Tools:\n\nTranscranial Magnetic Stimulation (TMS) using DEYMED DuoMAG XT will be used to measure Resting Motor Threshold (RMT), Motor Evoked Potential (MEP) Amplitude, and MEP Latency of the First Dorsal Interosseous (FDI) muscle.\n\nOnline Typing Test will be used to assess typing speed (words per minute) and accuracy (percentage of correct characters).\n\nIntervention:\n\nThe ME group will perform a 3-minute typing task. The AO group will observe a 3-minute first-person video of typing. The Control group will not receive any intervention between assessments.\n\nAll participants will undergo TMS and typing assessments twice, once before and once after the intervention.",[32],[408,409,410,411,412],"Transcranial magnetic stimulation","Cortical excitability","Action observation","Motor execution","Typing","2025-05-29",{"date":415,"type":38},"2025-06-06",{"date":417,"type":22},"2025-06-15",{"date":419,"type":22},"2025-07-30",{"name":421,"class":45},"University of Sharjah",{"id":423,"slug":424,"hasResults":11,"nctId":425,"briefTitle":426,"officialTitle":427,"acronym":4,"eligibilityCriteria":428,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":429,"targetDuration":4,"studyType":187,"phases":4,"briefSummary":431,"conditions":432,"keywords":436,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":443,"lastUpdatePostDateStruct":444,"startDateStruct":446,"completionDateStruct":448,"leadSponsor":450,"locationsCount":72},"100564495","sensory-interaction-and-balance-control-during-standing-and-walking-in-healthy-young-and-older-adults-100564495","NCT06629922","Sensory Interaction and Balance Control During Standing and Walking in Healthy Young and Older Adults","Sensory Interaction and Balance Control During Standing and Walking Under Challenging Conditions in Healthy Young and Older Adults","Inclusion Criteria:\n\n* Young adults who: a) aged between 18 to 35 years old and, b) have never been diagnosed with somatosensory, visual, and vestibular deficits as reported by the participants, will be invited to participate. Community-dwelling older adults who: a) are 65 years old and over and, b) have not fallen in the last 12 months will also be invited to participate.\n\nExclusion Criteria:\n\n* having had serious lower extremity injuries or operations in the past year,\n* having any neurological (stroke, epilepsy, Parkinson's disease, etc.), sensory (i.e. peripheral neuropathy, diminished sense of pain, etc.) or motor disorder that can interfere with the results of the study\n* Diagnosed vascular, respiratory, cardiac, orthopedic, or other disorders that affect the subject's ability to exercise safely,\n* Medication affecting exercise tolerance. Additionally, based on the CAREN High-End Systems contraindications and risk factors the following exclusion criteria will be applied to the participants: a) a body weight higher than the 135 kg, b) an inability to properly adjust the harness to the respective body part due to pregnancy, colostomy bags, skin lesions that cannot be protected appropriately and any other reason that prevents a proper, pain-free adjustment of the harness.",{"count":430,"type":22},64,"This project is designed to: a) develop a new test called UHasselt Locomotor Sensory Integration Test (UHLSINT) which would allow us to evaluate sensory interaction process in locomotion assess whether Locomotor CTSIB and to investigate whether UHLSINT is a reliable test to evaluate sensory interaction in both young and older adults, b) evaluate the difference in sensory interaction and balance performance between standing and walking between both young and older adults, c) examine the changes in sensory interaction process under challenging conditions such as perturbations, dual-task, and when both are present between both young and older adults, d) examine the association between overall fall risk defined by the single-large perturbations and sensory interaction processes used during all the trials in both age groups.\n\nIn order to achieve these aims, 10 trials will be conducted:\n\nTrial 1- Single-Large Perturbation in Standing Trial 2- Single-Large Perturbation in Walking Trial 3- Instrumented CTSIB Trial 4- Locomotor CTSIB Trial 5- Instrumented CTSIB + Perturbations Trial 6- Locomotor CTSIB + Perturbations Trial 7- Instrumented CTSIB + Auditory Stroop Test Trial 8- Locomotor CTSIB + Auditory Stroop Test Trial 9- Instrumented CTSIB + Perturbations + Auditory Stroop Test Trial 10- Locomotor CTSIB + Perturbations + Auditory Stroop Test\n\nTwo different treadmill perturbations will be applied in addition to the Instrumented CTSIB and UHLSINT: a) slip perturbations, b) continuous perturbations. An auditory stroop task will be applied in relevant trials.\n\nAll of the trials will be performed in CAREN High-End Systems (Motek Medical BV, Amsterdam, The Netherlands) which is a motion capture system that is equipped with a treadmill mounted on a 6 degree of freedom motion base, a 360º dome-shaped virtual reality (VR) screen, and a marker-based movement analysis system.",[433,32,434,435],"Healthy","Older Adults (65 Years and Older)","Elderly",[437,438,439,440,441,442],"sensory interaction","sensory reweighting","older adults","balance","fall risk","fall","2024-10-04",{"date":445,"type":38},"2024-10-08",{"date":447,"type":22},"2024-10-07",{"date":449,"type":22},"2026-12-25",{"name":451,"class":45},"Hasselt University"]