18F-choline Positron-emission-tomography - Computed-tomography Compared to Conventional Imaging for Localizing Diseased Parathyroid Glands in Primary Hyperparathyroidism

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorRegion Skane

About this trial

The goal of this open, single-center, prospective, randomized, clinical study is to compare imaging with \[18F\]fluoromethyl-dimethyl-2-hydroxyethylammonium (18F-choline) positron-emission-tomography - computed-tomography, 18F-ch-PETCT, to conventional imaging with ultrasonography and sestamibi scintigraphy in localizing diseased parathyroid glands in patients diagnosed with primary hyperparathyroidism, pHPT. The question this study aims to answer is: can 18-F-ch-PET-CT more precisely localize diseased parathyroid glands in patients with pHPT before surgery? The objective of the study is to help improve precision in parathyroid surgery, thereby increasing cure rates, minimizing complications, and shortening operation times.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Parathyroidectomy

    Procedure/Surgery

    Imaging with 18-F-choline-PET-CT

Treatment groups

88 Participants
are divided into 2 treatment groups
Group A: 18-F-choline-PETExperimental treatment 1 intervention
Group B: ConventionalActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Operation time

Operation time in minutes, skin-to-skin

Time frame
During surgery

Secondary outcomes

Other outcomes

Sponsors and contacts

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