2D:4D Digit Ratio and Urinary Stone Disease

ConditionUrinary Stone
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorEmrah Kızılay

About this trial

This prospective observational case-control study will investigate whether the 2D:4D digit ratio is associated with urinary stone disease. Adults undergoing non-contrast computed tomography at Malatya Training and Research Hospital will be classified as cases if kidney and/or ureteral stones are detected and as controls if no urinary stones are detected and there is no previous history of stone disease or stone surgery. The lengths of the second and fourth fingers of both hands will be measured using a digital caliper by two independent observers who are blinded to the participant group. The study will also examine whether the 2D:4D ratio is associated with recurrent stone disease, stone burden, and bilateral or multiple stones.

Eligibility criteria

Qualifiers

Age 18 years or older

Provision of written informed consent

Undergoing non-contrast computed tomography at Malatya Training and Research Hospital during the study period

For cases: presence of at least one kidney and/or ureteral stone on non-contrast computed tomography

Disqualifiers

Congenital deformity of the hands or fingers

History of hand or finger trauma, fracture, surgery, or amputation that may affect digit length measurement

Severe hand deformity, contracture, or advanced joint disease preventing reliable measurement

Incomplete, inadequate, or technically unreliable 2D:4D measurements

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

300 Participants
are grouped into 2 trial groups

Sponsors and collaborators

Emrah Kızılay

Lead sponsor

Malatya Governor Research Hospital

Sponsor institution