About this trial
This prospective observational case-control study will investigate whether the 2D:4D digit ratio is associated with urinary stone disease. Adults undergoing non-contrast computed tomography at Malatya Training and Research Hospital will be classified as cases if kidney and/or ureteral stones are detected and as controls if no urinary stones are detected and there is no previous history of stone disease or stone surgery. The lengths of the second and fourth fingers of both hands will be measured using a digital caliper by two independent observers who are blinded to the participant group. The study will also examine whether the 2D:4D ratio is associated with recurrent stone disease, stone burden, and bilateral or multiple stones.
Eligibility criteria
Qualifiers
Age 18 years or older
Provision of written informed consent
Undergoing non-contrast computed tomography at Malatya Training and Research Hospital during the study period
For cases: presence of at least one kidney and/or ureteral stone on non-contrast computed tomography
Disqualifiers
Congenital deformity of the hands or fingers
History of hand or finger trauma, fracture, surgery, or amputation that may affect digit length measurement
Severe hand deformity, contracture, or advanced joint disease preventing reliable measurement
Incomplete, inadequate, or technically unreliable 2D:4D measurements
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Sponsors and collaborators
Emrah Kızılay
Lead sponsor
Malatya Governor Research Hospital
Sponsor institution