Health Trials

3-Dimensional Optical Scanning to Assess and Monitor Malnutrition in Eating Disorders (3D-ED) Study

ConditionsAnorexia in AdolescenceAnorexia NervosaAnorexia Nervosa, AtypicalAnorexia Nervosa, Binge Eating/Purging TypeAnorexia Nervosa Restricting TypeAnorexia Nervosa With Significantly Low Body WeightBody Composition ChangesGrowth & DevelopmentMalnutrition SevereMalnutrition, Calorie
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age15-26
SponsorUniversity of California, San Francisco

About this trial

People with anorexia nervosa often become medically unstable because of severe malnutrition and require hospitalization for nutritional rehabilitation. Clinicians currently rely heavily on body weight to assess malnutrition, but body weight does not always reflect the severity of illness. This study will use infrared scanning to assess body composition in adolescents and young adults hospitalized with anorexia nervosa. Researchers will then examine how organ and tissue stores relate to the degree of malnutrition, predict nutritional needs and medical restoration in hospital, and recovery outcomes over the following year. The goal is to develop more individualized approaches to nutritional rehabilitation and improve recovery for individuals with malnutrition due to eating disorders.

Eligibility criteria

Qualifiers

Diagnosis of anorexia nervosa (AN) or atypical anorexia nervosa (AAN), restricting or purging subtype, per DSM-5

Age 15 to 26 years

vital signs: daytime heart rate below 50 bpm or nighttime heart rate below 45 bpm, blood pressure below 90/50 mm Hg, temperature below 36 C, orthostatic increase in heart rate above 20 bpm or decrease in systolic blood pressure above 20 mm Hg or decrease in diastolic blood pressure above 10 mm Hg from lying to standing, or median BMI below 75 percent; or

laboratory abnormality: AST above 40 IU/L, ALT above 30 IU/L, estimated GFR below 90 or cystatin C below 0.7 mg/L, albumin below 3.7 g/dL, or prealbumin below 20 mg/dL

Disqualifiers

Bulimia nervosa

Another primary diagnosis causing malnutrition (not an eating disorder)

Current active suicidality

Metal implants or devices that interfere with study procedures

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Sponsors and collaborators

University of California, San Francisco

Lead sponsor

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Collaborator

Denver Health and Hospital Authority

Collaborator

University of Hawaii

Collaborator

Source ClinicalTrials.gov