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"Salivary Melatonin and Cortisol Levels in Individuals with Bruxism"

ConditionBruxism
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorYuzuncu Yil University

About this trial

The effects of the hormones melatonin and cortisol, which play a highly effective role in regulating the sleep-wake cycle, on teeth grinding will be scientifically evaluated. Based on the research results, more effective methods for treating patients suffering from bruxism may be identified.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Individuals with systemic diseases that affect or may potentially affect saliva content, or those using medications that cause these effects, will not be included in the study

Trial population

ndividuals with and without bruxism

Trial design

Design model

Case-control

Time perspective

Cross-sectional

Treatments tested in this trial

  • The investigation of melatonin and cortisol levels in the saliva

    Diagnostic test

    In the related study, patient data from individuals who visited the Oral and Maxillofacial Radiology clinic at Van Yüzüncü Yıl University Faculty of Dentistry with complaints of bruxism will be used. The diagnosis of bruxism will be made based on clinical data. Diagnoses will be made by Dr. Sema KAYA using clinical findings such as patient history used for the current diagnosis of bruxism, tooth wear, tooth mobility, pain in the temporomandibular joint (TMJ), headaches, pain in the chewing muscles, hypertrophy, and a feeling of fatigue. Before taking the saliva samples, patients will be asked to rinse their mouths with sterile water, and then they will be asked to spit into sterile plastic containers. After approximately 3 mL of saliva is collected, it will be transferred to appropriate Eppendorf tubes and stored at -80°C. Melatonin and cortisol levels will later be analyzed using the enzyme-linked immunosorbent assay (ELISA) method.

Treatment groups

100 Participants
are divided into 2 treatment groups
Group A: 11 intervention
Group B: 21 intervention

Trial outcomes

Primary outcomes

1

levels of melatonin

individuals with bruxism

Time frame
Baseline assessment at the start of the study, follow-up assessments at 3 months and 6 months, with final data collection at 12 months.
2

levels of cortisol

individuals with bruxism

Time frame
Baseline assessment at the start of the study, follow-up assessments at 3 months and 6 months, with final data collection at 12 months.

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Yuzuncu Yil University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: