A Behavioral Application for Improving Smoking Cessation Among Smokers

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorFred Hutchinson Cancer Center

About this trial

This clinical trial compares two smartphone applications, called Actify! (A \& B) for improving smoking cessation outcomes in individuals who smoke. Actify! A is an app grounded in behavioral activation therapy, an evidence-based treatment for depression that can also be used to modify health behaviors such as smoking. The Actify! B app provides evidence-based tobacco cessation strategies based on current clinical guidelines.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age 18 or older

Currently smoke, averaging at least 5 cigarettes/day for the last 30 days

Interested in quitting smoking in the next 30 days

Experience downloading and using one or more apps on their smartphone

Disqualifiers

Self-report of currently receiving behavioral treatment for depression (e.g., psychotherapy or counseling, web- or app-based interventions); current use of pharmacotherapy for depression or for other mental health conditions that are not otherwise excluded is allowable (e.g., benzodiazepines, anticonvulsants, opioid agonists, antipsychotics)

Severe depression (PHQ-9 ≥ 20)

Current suicidal ideation reported on the PHQ-9

History of a suicide attempt

Trial design

Design model

Parallel

Treatments tested in this trial

  • Smartphone app-based Intervention (Actify! A app)

    Behavioral

    Use Actify! A app

  • Smartphone app-based Intervention (Actify! B app)

    Behavioral

    Use Actify! B app

  • Health Promotion and Education

    Other intervention

    Receive motivational messages and smoking cessation information via text messages

  • Survey Administration

    Other intervention

    Ancillary studies

Treatment groups

1,812 Participants
are divided into 2 treatment groups
Group A: Arm I (Actify! A app)Experimental treatment 3 interventions
Group B: Arm II (Actify! B app)Active comparator 3 interventions

Trial outcomes

Primary outcomes

1

Self-reported 30-day point prevalence abstinence (PPA) from cigarette smoking

Percentage of participants self-reporting no smoking over the previous 30 days

Time frame
At 6 months post-randomization

Secondary outcomes

1

Biochemically-confirmed 30-day PPA from cigarette smoking

Percentage of participants reporting no smoking over the previous 30 days, confirmed via carbon monoxide testing

Time frame
At 6 months post-randomization
2

Self-reported 7-day PPA from cigarette smoking

Percentage of participants reporting no cigarette smoking over the prior 7 days

Time frame
At 8 weeks post-randomization
3

Self-reported 7-day PPA from cigarette smoking

Percentage of participants reporting no cigarette smoking over the prior 7 days

Time frame
At 6 months post-randomization
4

Self-reported 7-day PPA from use of all nicotine/tobacco products except Food and Drug Administration (FDA)-approved medications

Percentage of participants reporting no smoking over the prior 7 days and no use of any other nicotine/tobacco product except FDA-approved medications (e.g, nicotine patch or gum)

Time frame
At 8 weeks post-randomization

Other outcomes

Sponsors and contacts

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Fred Hutchinson Cancer Center

Lead sponsor

National Institute on Drug Abuse (NIDA)

Collaborator

This trial is not recruiting at the moment. You can still explore other options: