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A Clinical Study on the Effect of Cardiopulmonary Function and Quality of Life in Patients With Acute Coronary Syndrome Complicated by Heart Failure by "Lying-Sitting-Standing" Sequential Baduanjin

ConditionsACS (Acute Coronary Syndrome)HF - Heart Failure
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeUp to 85
SponsorXiling Qi

About this trial

This study investigates the effects of a sequential "lying-sitting-standing" Baduanjin intervention on patients with acute coronary syndrome complicated by heart failure. By evaluating cardiopulmonary function and quality of life through indicators such as echocardiography, NT-proBNP, 6MWT, NYHA classification, and SF-36, we aim to compare its efficacy with conventional treatment. The objective is to provide new insights for early cardiac rehabilitation strategies in patients with acute coronary syndrome complicated by heart failure

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients meeting the diagnostic criteria for ACS (including unstable angina, non-ST-segment elevation myocardial infarction, and ST-segment elevation myocardial infarction)

Complicated by heart failure during hospitalization

Age ≤ 85 years

Muscle strength ≥ grade 3

Disqualifiers

Patients with persistent heart failure symptoms or NYHA functional class IV despite optimal pharmacological therapy;

Patients with contraindications to cardiac rehabilitation, such as uncontrolled hypertension, uncontrolled arrhythmias, or hemodynamic instability;

Patients with untreated structural heart disease, such as heart failure caused by valvular heart disease or congenital heart disease;

Patients in the acute phase of various diseases, such as severe infection, deep vein thrombosis, or severe hepatic or renal failure;

Trial design

Design model

Parallel

Treatments tested in this trial

  • standard treatment and routine rehabilitation nursing guidance

    Behavioral

    standard treatment and routine rehabilitation nursing guidance

  • "Lying-Sitting-Standing" Sequential Baduanjin

    Behavioral

    "Lying-Sitting-Standing" Sequential Baduanjin

Treatment groups

65 Participants
are divided into 2 treatment groups
Group A: standard treatment and routine rehabilitation nursing guidancePlacebo comparator 1 intervention
Group B: "Lying-Sitting-Standing" Sequential BaduanjinExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Patients were stratified based on their 6-minute walk test distance

The 6-minute walk test is an objective indicator for evaluating exercise tolerance in patients with heart failure, representing the total distance a patient can walk in 6 minutes. The results are categorized into four grades based on the distance covered: \<300 m, 300-374.9 m, 375-449.9 m, and ≥450 m.

Time frame
From enrollment to the end of the 12-week treatment
2

NYHA（New York Heart Association）classification of cardiac function

The New York Heart Association (NYHA) Functional Classification, proposed in 1928 and still in use today, categorizes patients into classes Ⅰ through Ⅳ, with class Ⅰ representing the best condition and class Ⅳ the worst.

Time frame
From enrollment to the end of the 12-week treatment
3

Left ventricular ejection fraction (LVEF) on echocardiography

Ejection fraction is a ratio reflecting the efficiency of cardiac pumping, defined as the percentage of blood volume pumped out by the left ventricle during each contraction (stroke volume, SV) relative to its end-diastolic volume (EDV). It is measured using the Simpson's method on echocardiography.

Time frame
From enrollment to the end of the 12-week treatment
4

C-reactive protein levels

Unit:mg/L

Time frame
From enrollment to the end of the 12-week treatment

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Xiling Qi

Lead sponsor

Second Hospital of Shanxi Medical University

Sponsor institution

Source ClinicalTrials.gov
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