The study evaluates the effect of chondroitin sulfate derived from fermentation (MyCondro™) and bovine chondroitin sulfate, on the health and function of the skeletal system ex vivo, including cartilage, joint capsule, and bone tissue. The primary aim of the study is to determine the influence of human sera enriched with metabolites resulting from the ingestion of the ingredients on the metabolism of human primary cells of cartilage (chondrocytes), joint capsule (synoviocytes) and bone tissue (osteoblasts). Furthermore, the absorption kinetics of MyCondro™ and Bovine CS will be described.
Men.
18-35 years old (terminals included).
Liver test in the reference standards.
Renal assessment in the reference standards.
All types of vaccination under one month.
Alcohol consumption above WHO standards (>3 glasses of alcohol per day for men).
Ongoing treatment (medication, dietary supplement or probiotic) and within 4 weeks prior to inclusion.
Known pathology (including seasonal).
Lesaffre International
Lead sponsor
Clinic'n'Cell
Collaborator
University Hospital, Clermont-Ferrand
Collaborator