A Comparative Study Between Laser and Manual Removal of Corneal Epithelium for Photorefractive Keratectomy

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssiut University

About this trial

Photorefractive keratectomy (PRK) is a laser eye surgery used to ablate the corneal stroma to correct visual refractive errors . PRK was developed in 1983 by Dr. Steven Trokel and colleagues and first performed in 1987 by Dr. Theo Seiler in Berlin. After receiving approval by the US Food and Drug Administration (FDA) in 1996, PRK was briefly the preferred surgical treatment of ametropia as it provided more predictable and stable results than incisional keratotomy. However, the number of PRK procedures fell in the late 1990s with the growing popularity of laser in situ keratomileusis (LASIK).

The study aims to compare the visual and refractive outcomes along with the pain score and patient satisfaction after photorefractive keratectomy in patients who underwent transepithelial or mechanical removal technique

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

• Age : older than 18 years old .

Gender: Include both males and females.

Stable refraction for at least 12 months .

Intraocular pressure less than 21mmHg.

Disqualifiers

_ patients with any eye disease (significant cataract or unstable glaucoma )

uncontrolled external disease such as blepharitis, dry eye syndrome, and atopy/allergy.

patients with Keratoconus and other abnormalities of the cornea such as corneal ectasias , thinning , edema , interstitial or neurotrophic keratitis and extensive vascularisation .

Patients with active systemic connective tissue disease such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA)

Trial population

Patients in the age group between 18 and 45 years will be included in this study. Subjects selected, which will consist of patients with myopia ( less than - 6 D ) will be divided into 2 groups.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

64 Participants
are grouped into 2 trial groups
Group A: group A
Group B: group B

Trial outcomes

Primary outcomes

1

visual acuity

best corrected visual acuity (BCVA) will be observed for at least 6 months postoperatively.

Time frame
6 month

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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