A Comparative Study of Preoperative Carbohydrate Loading Dose and Fasting on Postoperative Recovery Time in Elective Abdominal Surgery Patients

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-60
SponsorGulab Devi Hospital

About this trial

This randomized controlled trial aims to compare the effect of preoperative carbohydrate loading versus standard overnight fasting on postoperative recovery time in patients undergoing elective abdominal surgery. A total of 144 admitted patients will be randomly assigned to either receive a preoperative carbohydrate drink or follow routine fasting protocols. The primary objective is to evaluate differences in postoperative recovery time between the two groups. Secondary outcomes include length of hospital stay, postoperative complications, and patient comfort. The findings of this study may help optimize preoperative fasting guidelines and improve patient recovery outcomes.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

• Patients aged 20-60

ASA I-II classification.

Elective open or laparoscopic abdominal surgeries.

Disqualifiers

• Diabetes mellitus or impaired fasting glucose.

Emergency surgeries.

Patients with hepatic or renal dysfunction.

Patients on corticosteroids or insulin-sensitizing agents.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Patients will be given 400 mL of a carbohydrate-rich clear drink (10% daxtrosewater) approximately 2-3 hours before induction of anesthesia, according to ERAS guidelines.

    Dietary supplement

    Most previous studies have evaluated preoperative carbohydrate loading in mixed surgical populations or in settings outside Pakistan. Limited local data exist specifically for elective abdominal surgery patients in a single-center Pakistani tertiary care hospital setting. Thisstudy focuses on comparing a standardized carbohydrate loading dose with conventional fasting and assessing its direct impact on postoperative recovery time in your local population. surgery patients specifically It uses a standardized carbohydrate loading dose It compares against the routinely practiced prolonged fasting protocol It is conducted in a single-center local hospital population, where local evidence is limited It focuses on postoperative recovery time as the primary clinical outcome

  • Standard pre operative fasting

    Other intervention

    Patients in this group will follow the routine preoperative fasting protocol according to hospital and anesthesia guidelines, including overnight fasting from solids and clear liquids before elective abdominal surgery. No preoperative carbohydrate loading will be give

Treatment groups

144 Participants
are divided into 2 treatment groups
Group A: Pre operative carbohydrate Loading groupExperimental treatment 1 intervention
Group B: Standard preoperative fasting groupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Post operative insuline resistance

To evaluate the effect of preoperative oral carbohydrate loading compared with standard fasting on postoperative insulin resistance in patients undergoing elective abdominal surgery. Insulin resistance will be assessed by measuring fasting blood glucose and serum insulin levels preoperatively and postoperatively, and calculating insulin resistance using the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR).

Time frame
24 hours after surgery

Secondary outcomes

1

Time to first oral intake

To compare the duration from completion of surgery until the patient tolerates first oral intake (clear fluids or oral diet) between the preoperative carbohydrate loading group and the standard fasting group. This outcome reflects early postoperative gastrointestinal recovery and readiness for oral feeding.

Time frame
24 hours after surgery

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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