A Machine Learning Approach to Identify Patients With Resected Non-small-cell Lung Cancer With High Risk of Relapse

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Toulouse

About this trial

Early-stage non small cell lung cancer represents 20-30% of all non small cell lung cancer and is characterized by a high survival probability after surgical resection. However, considering stage IA-IIIA non small cell lung cancer, a relapse rate of about 50% is observed, with a different survival probability on the basis of tumor node metastasis status, although patients within the same tumor node metastasis stage exhibit wide variations in recurrence rate. There are currently no validated prognostic biomarkers able to identify patients with a high risk of relapse.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patient with an early stage of non small cell lung cancer

Indication of surgical resection

Patient able to understand and give his consent

Patient affiliated to the health insurance

Disqualifiers

Patient with another cancer in the last 5 years

Patient with an allergy to the contrast medium

Patient under legal protection

Trial population

Patient with an early stage of non small cell lung cancer with an indication of surgical resection

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Resected non small cell lung cancer

    Other intervention

    plasma sample, tissue sample and computed tomography scan images

Treatment groups

60 Participants
are divided into 1 treatment group
Group A: Resected early stage non small cell lung cancer1 intervention

Trial outcomes

Primary outcomes

1

Algorithm for disease free survival

Analysis on a training cohort of resected early-stage non small cell lung cancer

Time frame
18 months

Secondary outcomes

Other outcomes

Sponsors and contacts

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