A Major Determinant Focused on the ECG or Echocardiogram for PICM and Its Clinical Outcome (PICM Syndrome)

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age20+
SponsorEulji University Hospital

About this trial

Chronic right ventricular pacing has a deleterious effect on left ventricular (LV) function, namely pacing-induced cardiomyopathy (PICM). Several parametes make difference of effect on the occurrence of PICM and its subsequent clinical outcomes. In particular, recognition of a major determinant focused on the ECG or echocardiographic parameters including strain or genetic factor for occurrence of PICM may lead to better identification of patients at high risk. Investigators prospectively enroll a participant with documented high risk of PICM and clinically follow-up to idenify clinical impact of PICM (PICM syndrome) over a long period of time.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Willng to participate in the study and able to sign informed consent

Undertaken ECG and echocardiogram including strain before and after device implantation

Disqualifiers

Less than 18 years of age

Being pregnant or plan to become pregnant

Advanced heart failure waiting in heart transplantation

Have a life expectancy of less than 1 year

Trial population

The study will enroll at least 1000 device patients from multi-centers in order to identify and assess a determinant of PICM and its clinical outcomes (PICM syndrome)

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Heart failure diagnosis and treatment

Occurrence of heart failure symptom, diagnosis and treatment

Time frame
5 years

Secondary outcomes

1

Atrial and Ventricular arrhythmia diagnosis, heart failure admisssion and all-caused mortality

Occurrence of atrial, ventricular arrhythmia, hear failure admission and all-cause mortality

Time frame
5 years

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Eulji University Hospital

Lead sponsor

Chung-Ang University Hosptial, Chung-Ang University College of Medicine

Sponsor institution

Chungnam National University Hospital

Collaborator

Chungbuk National University Hospital

Collaborator

Dankook University

Collaborator

Chung-Ang University Hosptial, Chung-Ang University College of Medicine

Collaborator