A Multiple-center Study on the Effect of Different Ways of Lymph Node Dissection on the Prognosis of Ground Glass Nodules Smaller Than 3cm and With More Than 50% Solid Components

ConditionProgression

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-75

SponsorShanghai Zhongshan Hospital

About this trial

A multiple-center study on the effect of different ways of lymph node dissection on the prognosis of less than 3cm ground glass nodules with more than solid components

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Aged between 18 and 75 years;

GGO is diagnosed by lung CT and failure to subside after 3 months (the patient having been re-examined by thin-section CT);

The maximum diameter of the GGO is smaller than 3cm;

The maximum diameter of the solid component in the GGO is more than 50%;

Disqualifiers

Patients with a history of using immunosuppressive or hormonal drugs;

Patients receiving radiotherapy or chemotherapy;

Patients who fail to comply with our follow-up strategy;

Other situations that are not in conformity with the standards and requirements of this trial.

Trial design

Design model

Parallel

Treatments tested in this trial

Lymphadenectomy
Procedure/Surgery
Patients with ground glass nodules smaller than 3cm and with more than 50%solid components would randomly assigned to selective lymphadenectomy group or systematic lymph node dissection group

Treatment groups

1,500 Participants

are divided into 2 treatment groups

Group A: Selective lymphadenectomyExperimental treatment 1 intervention

Group B: Systematic lymph node dissectionNo intervention 0 interventions

Trial outcomes

Primary outcomes

overall survival (OS)

five year overall survival

Time frame

5 years

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Shanghai Zhongshan Hospital

Lead sponsor

Source ClinicalTrials.gov

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