Liberation from mechanical ventilation involves three steps: weaning, readiness assessment, and extubation. Readiness is determined using clinical criteria such as improvement of the underlying condition, hemodynamic stability, and adequate respiratory effort. Successful extubation is defined as not requiring invasive support within 48 hours. Due to the complexity of ICU patients, various clinical parameters and multi-component scores have been developed to predict extubation success. This study aims to develop and evaluate a multi-component score, the Readiness for EXtubation score (REXs), to predict extubation readiness in ICU patients under invasive mechanical ventilation.
None
Patients without legal guardian consent.
Tracheostomized patients.
Patients enrolled in other studies.
Individuals with diaphragmatic pacers.
Patients on mechanical ventilation admitted to the Intensive Care Unit
Cohort
Prospective
Not listed
Extubation failure in 48 hours
Extubation failure within 48 hours is defined as the need for reintubation or resumption of mechanical ventilation within two days after planned extubation, indicating the patient could not sustain spontaneous breathing independently.
Extubation failure in 72 hours
Extubation failure within 72 hours is defined as the need for reintubation or resumption of mechanical ventilation within three days after planned extubation, indicating the patient could not sustain spontaneous breathing independently.
Extubation failure in 24 hours
Patients included who present failure in extubation from mechanical ventilation in the first 24 hours post extubation and require orotracheal intubation
Length of intensive care stay
Length of intensive care stay refers to the total number of days a patient spends in the intensive care unit (ICU) from admission to discharge, reflecting the severity of illness and recovery progress.
Length of hospital stay
Length of hospital stay (LOS) refers to the total number of days a patient remains admitted in the hospital from initial admission until final discharge, serving as an important indicator of treatment efficiency and healthcare resource utilization.
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Medipol University
Lead sponsor
International Association of Non Invasive Ventilation
Collaborator
International Academy of Non Invasive Ventilation
Collaborator
International College of Experts of Non Invasive Ventilation
Collaborator