A New Ultrasonographic Tool to Assess Pulmonary Strain in the ICU

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentre hospitalier de l'Université de Montréal (CHUM)

About this trial

The primary objective of the study is to create a small dataset of regional pulmonary strain values in patients suffering from pulmonary diseases under mechanical ventilation in an intensive care setting.

Hypothesis: The analysis of lung ultrasonographic sequences using speckle-tracking allows the determination of local pleural strain in 4 predetermined pulmonary areas in mechanically ventilated patients suffering from pulmonary diseases.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adult intensive care patients under mechanical ventilation suffering from a pulmonary disease with a static lung compliance of less than 40 mL/cm H2O.

Disqualifiers

Obesity (Body Mass Index superior to 30 kg/m2)

Previous thoracic procedure (chest tube, thoracotomy, thoracoscopy)

Intra-abdominal pressure inferior to 15 mm Hg (if available)

Previous participation to the study

Trial population

Adult Intensive care patients under mechanical ventilation suffering from a pulmonary disease.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Lung ultrasonography

    Procedure/Surgery

    Mechanically ventilated patients suffering from pulmonary diseases will undergo a lung ultrasonography during their stay in the intensive care unit (ICU)

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Average absolute lateral deformation

Change in percentage from baseline expiratory value

Time frame
At the end of study on Day 1

Secondary outcomes

1

Cumulated range of absolute lateral deformation

Change in percentage from baseline expiratory value

Time frame
At the end of study on Day 1
2

Average absolute axial deformation

Change in percentage from baseline expiratory value

Time frame
At the end of study on Day 1
3

Cumulated range of absolute axial deformation

Change in percentage from baseline expiratory value

Time frame
At the end of study on Day 1
4

Average von mises

Change in percentage from baseline expiratory value

Time frame
At the end of study on Day 1

Other outcomes

Sponsors and contacts

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