A New Way to Share Radiation Therapy Plans Between Doctors, CORRECT Trial

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorWake Forest University Health Sciences

About this trial

This clinical trial tests a new way to share radiation therapy plans using the Collaborative Oncology between Radiologists and Radiation oncologists for the Evaluation of Contoured Targets (CORRECT) workflow to improve communication and collaboration between radiation oncologists (ROs) and radiologists when determining cancer targets for radiation treatment. Systemic barriers limit critical communication between radiation oncologists and radiologists and can lead to both under and overdosing of radiation therapy (RT) tumor targets and failures to properly interpret post-treatment imaging. The limited formal diagnostic radiology training of many providers can make differentiating normal from disease imaging findings during target determination difficult, especially in complex disease sites like the lung, head, and neck. Inaccurate target determination may result in cancer return, excess toxicity, or both. Likewise, radiologists who cannot access prior RT plans may mistake expected RT changes for recurrent cancer or overlook true progression. The CORRECT workflow was developed by ROs and radiologists to address RO-radiology communication barriers by facilitating sharing of comprehensive RT target contours during RT planning. The CORRECT workflow begins with the normal process of RO target contouring. Computed tomography (CT) images are then fused with RT targets and pushed to a pre-designated Picture Archiving and Communications System (PACS) software folder accessible by the radiology department. The radiologist can then review the fused images at their chosen time and annotate images to indicate potential deviations (e.g., not avoiding normal tissue or not including all tumor). The RO reviews the annotated images and decides if any changes to treatment targets are needed for the final treatment plan. Through this independent, asynchronous review of high-quality images, CORRECT overcomes many of the limitations of existing communication methods between RO-radiologist, fostering a more collaborative, efficient, and precise approach to cancer treatment planning.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

PRACTICE: Must provide radiation therapy for ≥ 3 patients per month with lung cancer or head & neck cancer

PRACTICE: At least one radiation oncologist and one radiologist (in house, contracted, etc.) at the practice willing to participate, but may have multiple participants at the practice

PRACTICE: Radiation oncologist/radiologist team must use Picture Archiving and Communication System (PACS) software at this practice

RADIATION ONCOLOGIST (NON-PATIENT): Must have been in independent practice (i.e., performing duties without preceptor oversight) for a minimum of six months

Disqualifiers

PRACTICE: Participation by the Community Site or Minority/Underserved Community Site in another National Cancer Institute (NCI) Community Oncology Research Program (NCORP) Cancer Care Delivery Research (CCDR) U34-supported protocol funded in NCI fiscal year 2025 or later. (Note: WF- 2301CD CONNECT is exempt from this policy, as it was funded prior to NCI fiscal year 2025.)

RADIATION ONCOLOGIST (NON-PATIENT): Planning to leave their position at this practice within the next 12 months

RADIATION ONCOLOGIST (NON-PATIENT): Providing service on a temporary basis (i.e., locum tenens providers)

RADIOLOGIST (NON-PATIENT): Planning to leave their position at this practice within the next 12 months

Trial design

Design model

Single group

Treatments tested in this trial

  • Training and Education

    Behavioral

    Receive training and practice cases on CORRECT workflow

  • Communication Intervention

    Other intervention

    Use CORRECT workflow

  • Survey Administration

    Other intervention

    Ancillary studies

  • Interview

    Other intervention

    Ancillary studies

  • Electronic Health Record Review

    Other intervention

    Ancillary studies

Treatment groups

194 Participants
are divided into 1 treatment group
Group A: Health Services Research (CORRECT workflow)Experimental treatment 5 interventions

Trial outcomes

Primary outcomes

1

The return of radiology feedback via Collaborative Oncology between Radiologists and Radiation oncologists for the Evaluation of Contoured Targets (CORRECT) (feasibility)

If \> 50% of patients have target feedback returned to the radiation oncologist within 2 business days, this workflow will be considered feasible in community practice.

Time frame
Within 2 business days from receipt of initial radiation therapy (RT) targets

Secondary outcomes

1

Time (in business days) required to install the information technology (IT) application

Will be assessed at each practice as tracked on the CORRECT IT data form

Time frame
During study start-up prior to the enrollment of first patient case; up to 60 days after CIRB approval at the practice.
2

The number and proportion of cases per practice with reports of technical issues requiring centralized IT or CORRECT study team assistance

Will be assessed at each practice as tracked on the CORRECT IT data form.

Time frame
During RT planning for each patient; over the 9 months of of patient accrual
3

Percentage of approached patients who declined consent

Will be assessed at each practice as tracked on the Patient Refusal form.

Time frame
During screening and enrollment over the 9 months of patient accrual
4

Acceptability of the CORRECT workflow.

Will be assessed using the Acceptability of Intervention Measure. Will be collected on the post-study radiation oncologist/radiologist survey. Scale has four items measured on a Likert scale from 1 (completely disagree) to 5 (completely agree). The four items are averaged to obtain a final score.

Time frame
Up to 2 months after patient enrollment has concluded

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Wake Forest University Health Sciences

Lead sponsor

National Cancer Institute (NCI)

Collaborator

This trial is not recruiting at the moment. You can still explore other options: