About this trial
This clinical trial tests a new way to share radiation therapy plans using the Collaborative Oncology between Radiologists and Radiation oncologists for the Evaluation of Contoured Targets (CORRECT) workflow to improve communication and collaboration between radiation oncologists (ROs) and radiologists when determining cancer targets for radiation treatment. Systemic barriers limit critical communication between radiation oncologists and radiologists and can lead to both under and overdosing of radiation therapy (RT) tumor targets and failures to properly interpret post-treatment imaging. The limited formal diagnostic radiology training of many providers can make differentiating normal from disease imaging findings during target determination difficult, especially in complex disease sites like the lung, head, and neck. Inaccurate target determination may result in cancer return, excess toxicity, or both. Likewise, radiologists who cannot access prior RT plans may mistake expected RT changes for recurrent cancer or overlook true progression. The CORRECT workflow was developed by ROs and radiologists to address RO-radiology communication barriers by facilitating sharing of comprehensive RT target contours during RT planning. The CORRECT workflow begins with the normal process of RO target contouring. Computed tomography (CT) images are then fused with RT targets and pushed to a pre-designated Picture Archiving and Communications System (PACS) software folder accessible by the radiology department. The radiologist can then review the fused images at their chosen time and annotate images to indicate potential deviations (e.g., not avoiding normal tissue or not including all tumor). The RO reviews the annotated images and decides if any changes to treatment targets are needed for the final treatment plan. Through this independent, asynchronous review of high-quality images, CORRECT overcomes many of the limitations of existing communication methods between RO-radiologist, fostering a more collaborative, efficient, and precise approach to cancer treatment planning.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
PRACTICE: Must provide radiation therapy for ≥ 3 patients per month with lung cancer or head & neck cancer
PRACTICE: At least one radiation oncologist and one radiologist (in house, contracted, etc.) at the practice willing to participate, but may have multiple participants at the practice
PRACTICE: Radiation oncologist/radiologist team must use Picture Archiving and Communication System (PACS) software at this practice
RADIATION ONCOLOGIST (NON-PATIENT): Must have been in independent practice (i.e., performing duties without preceptor oversight) for a minimum of six months
Disqualifiers
PRACTICE: Participation by the Community Site or Minority/Underserved Community Site in another National Cancer Institute (NCI) Community Oncology Research Program (NCORP) Cancer Care Delivery Research (CCDR) U34-supported protocol funded in NCI fiscal year 2025 or later. (Note: WF- 2301CD CONNECT is exempt from this policy, as it was funded prior to NCI fiscal year 2025.)
RADIATION ONCOLOGIST (NON-PATIENT): Planning to leave their position at this practice within the next 12 months
RADIATION ONCOLOGIST (NON-PATIENT): Providing service on a temporary basis (i.e., locum tenens providers)
RADIOLOGIST (NON-PATIENT): Planning to leave their position at this practice within the next 12 months
Trial design
Single group
Treatments tested in this trial
Training and Education
BehavioralReceive training and practice cases on CORRECT workflow
Communication Intervention
Other interventionUse CORRECT workflow
Survey Administration
Other interventionAncillary studies
Interview
Other interventionAncillary studies
Electronic Health Record Review
Other interventionAncillary studies
Treatment groups
Trial outcomes
Primary outcomes
The return of radiology feedback via Collaborative Oncology between Radiologists and Radiation oncologists for the Evaluation of Contoured Targets (CORRECT) (feasibility)
If \> 50% of patients have target feedback returned to the radiation oncologist within 2 business days, this workflow will be considered feasible in community practice.
Secondary outcomes
Time (in business days) required to install the information technology (IT) application
Will be assessed at each practice as tracked on the CORRECT IT data form
The number and proportion of cases per practice with reports of technical issues requiring centralized IT or CORRECT study team assistance
Will be assessed at each practice as tracked on the CORRECT IT data form.
Percentage of approached patients who declined consent
Will be assessed at each practice as tracked on the Patient Refusal form.
Acceptability of the CORRECT workflow.
Will be assessed using the Acceptability of Intervention Measure. Will be collected on the post-study radiation oncologist/radiologist survey. Scale has four items measured on a Likert scale from 1 (completely disagree) to 5 (completely agree). The four items are averaged to obtain a final score.
Sponsors and contacts
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Wake Forest University Health Sciences
Lead sponsor
National Cancer Institute (NCI)
Collaborator
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