A Platform Study for solId orgaN CancERs

ConditionsCancerSurgery
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age16-100
SponsorUniversity of Liverpool

About this trial

Generating bespoke biosampling protocols for individual tumour specific translational projects is onerous, cumbersome and inefficient. This study aims to provide a broad platform to maximise the unique access to biopsy and resected tumour specimens available from cancer patients to provide a high-quality and efficient source of biosamples for specific translational projects. Access to historical FFPE samples and clinical data, as well as prospective fresh tissue samples, will allow interrogation of the underlying biology of these cancers. Matched pseudoanonymised clinical and radiological data will allow the development of rich high-yield datasets.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Biopsy or surgical resection as standard of care

Disqualifiers

Refusal or inability to consent, paediatric patients

Trial population

All patients with a solid organ malignancy requiring surgery or biopsy as part of their routine clinical care as decided by the specialist MDT.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Biosampling

    Other intervention

    Biosampling of blood/tumour/adjacent normal tissue

Treatment groups

2,000 Participants
are divided into 1 treatment group
Group A: Patients with solid organ cancer1 intervention

Trial outcomes

Primary outcomes

1

Biosample procurement

Patient biosamples delivered via platform

Time frame
4 years

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Liverpool

Lead sponsor

Countess of Chester NHS Foundation Trust

Collaborator

Liverpool University Hospitals NHS Foundation Trust

Collaborator

Clatterbridge Centre for Oncology

Collaborator

Liverpool Heart and Chest Hospital NHS Foundation Trust

Collaborator

Liverpool Womens Hospital

Collaborator