About this trial
The goal of this observational study is to develop and validate a predictive model for prolonged mechanical ventilation (PMV) following acute type A aortic dissection (ATAAD) surgery.
The main questions it aims to answer are:
1. To validate the predictive performance of the model for PMV after ATAAD surgery 2. To assess the proportion of PMV among patients undergoing ATAAD surgery 3. To evaluate the ICU length of stay and operative mortality in patients with PMV following ATAAD surgery
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age ≥18 years;
Diagnosis of acute type A aortic dissection (ATAAD) confirmed by computed tomography angiography and echocardiography;
Patients who underwent aortic surgery requiring cardiopulmonary bypass (CPB), were admitted to the surgical intensive care unit (SICU), and received mechanical ventilation.
Disqualifiers
Reintubation;
Intraoperative death or failure to survive beyond 72 hours postoperatively;
Pregnancy;
Severe comorbidities (e.g., lung cancer);
Trial population
ATAAD postoperative patients admitted to SICU
Trial design
Cohort
Retrospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
The predictive performance of the model for prolonged mechanical ventilation (PMV) following acute type A aortic dissection (ATAAD) surgery
The predictive performance of PMV following ATAAD surgery includes its discriminative ability and calibration ablility.
The proportion of patients with PMV
The proportion of patients with PMV refers to the proportion of patients with PMV among the total included ATAAD postoperative patients. PMV is defined as postoperative mechanical ventilation lasting more than 72 hours
Secondary outcomes
ICU length of stay (ICU-LOS)
ICU length of stay was defined as the length of time spent in ICU from surgery to discharge or death.
surgery-related mortality
surgery-related mortality encompassed any death occurring during the index hospitalization (even beyond 30 days) or after discharge but before postoperative day 30.
Sponsors and contacts
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