The late-stage forms of degenerative osteoarthritis (OA) are very debilitating and less affordable to therapy. The main objective is to identify early onset symptoms of hand OA patients through imaging techniques (such as ultrasound and MRI). Our primary endpoint is to specify patients with high risk of radiological profression (X-ray).
None
patients suffering from rheumatoid arthritis, rheumatoid psoriasis or any other inflammatory rheumatism
patients suffering from metabolic diseasis such as gout, hemochromatosis, Wilson's disease; or from congenital disease such as displasie, osteogenesis,
Presence of advanced radiographic osteoarthritis based in Kellgreen Lawrence score (=4) in one joint among the 10 previous sites.
Not able to provide a sample of blood for any reasons
Single group
Identification of subgroups of patients with early AD with risk of progression
Diagnostic testClinical examination with questionnaires, Biological collection, Imaging (radiography, densitometry, ultrasound, and MRI)
Radiographic progression judged by the number of joints whose KL index has evolved
Evaluation of prognostic role of imaging factors in x-ray progression of early onset hand osteoarthritis
The number of painful / swollen or deformed joints in the hands.
Photographs of the patients' hands will be taken at each visit.
The location of painful / swollen or deformed joints in the hands.
Photographs of the patients' hands will be taken at each visit.
The intensity of pain over the last 48 hours
The intensity of pain over the last 48 hours will be assessed by the patient at each visit on a visual analogue scale (VAS). EVA pain (visual analogue scale over 100 mm): one-dimensional measurement of the intensity of pain. EVA pain is a continuous scale consisting of a horizontal line from 0 (no pain) to 100 mm (maximum pain)
The activity of the disease over the last 48 hours
The activity of the disease over the last 48 hours will be evaluated at each visit by the patient and the doctor on a visual analog scale from 0 (no pain) to 100 mm (maximum pain)
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