About this trial
Polyetheretherketone has become one of the most important material choices for cranioplasty surgery. It has been shown that conventional ultrasound can be performed through the polyetheretherketone material for the examination of brain tissue and ventricular morphology. Transcranial doppler ultrasound can obtain good images of cerebral hemodynamic parameters in patients through polyetheretherketone-covered temporal window. This trial is a clinical prospective observational study in which cases treated with polyetheretherketone cranioplasty, and transcranial doppler ultrasonography is performed preoperatively and 10 days postoperatively, and data were collected mainly including bilateral hemodynamic parameters of middle cerebral artery(MCA), terminal internal carotid artery(TICA), (anterior communicating artery)ACA, and posterior cerebral artery(PCA) (Vs, Vd, Vm, PI index, RI index) from temporal window.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age of 18 years or older;
Proposed polyetheretherketone cranioplasty;
Incomplete cranial bone in the lateral temporal window;
Signed informed consent for surgery and informed consent for research.
Disqualifiers
None
Trial population
1. Age of 18 years or older; 2. Proposed polyetheretherketone cranioplasty; 3. Incomplete cranial bone in the lateral temporal window.
Trial design
Other
Prospective
Treatments tested in this trial
TCD group
DeviceTranscranial Doppler ultrasound to examine bilateral hemodynamic parameters of middle cerebral artery(MCA), terminal internal carotid artery(TICA), (anterior communicating artery)ACA, and posterior cerebral artery(PCA) (Vs, Vd, Vm, PI index, RI index) from temporal window
Treatment groups
Trial outcomes
Primary outcomes
transcranial doppler ultrasonography parameters before and after cranioplasty
transcranial doppler ultrasonography's hemodynamic parameters: Pulse Index(PI) of middle cerebral artery(MCA), terminal internal carotid artery(TICA), anterior communicating artery(ACA), and posterior cerebral artery(PCA) from bilateral temporal window before and after polyetheretherketone cranioplasty. PI=(Vs - Vd )/ Vm。
Sponsors and contacts
Click on the lead sponsor to view all of their trials.