A Prospective Observational Study of Transcranial Doppler Ultrasound in the Assessment of Cerebral Blood Flow After Polyetheretherketone Cranioplasty

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorRenJi Hospital

About this trial

Polyetheretherketone has become one of the most important material choices for cranioplasty surgery. It has been shown that conventional ultrasound can be performed through the polyetheretherketone material for the examination of brain tissue and ventricular morphology. Transcranial doppler ultrasound can obtain good images of cerebral hemodynamic parameters in patients through polyetheretherketone-covered temporal window. This trial is a clinical prospective observational study in which cases treated with polyetheretherketone cranioplasty, and transcranial doppler ultrasonography is performed preoperatively and 10 days postoperatively, and data were collected mainly including bilateral hemodynamic parameters of middle cerebral artery(MCA), terminal internal carotid artery(TICA), (anterior communicating artery)ACA, and posterior cerebral artery(PCA) (Vs, Vd, Vm, PI index, RI index) from temporal window.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age of 18 years or older;

Proposed polyetheretherketone cranioplasty;

Incomplete cranial bone in the lateral temporal window;

Signed informed consent for surgery and informed consent for research.

Disqualifiers

None

Trial population

1. Age of 18 years or older; 2. Proposed polyetheretherketone cranioplasty; 3. Incomplete cranial bone in the lateral temporal window.

Trial design

Design model

Other

Time perspective

Prospective

Treatments tested in this trial

  • TCD group

    Device

    Transcranial Doppler ultrasound to examine bilateral hemodynamic parameters of middle cerebral artery(MCA), terminal internal carotid artery(TICA), (anterior communicating artery)ACA, and posterior cerebral artery(PCA) (Vs, Vd, Vm, PI index, RI index) from temporal window

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

transcranial doppler ultrasonography parameters before and after cranioplasty

transcranial doppler ultrasonography's hemodynamic parameters: Pulse Index(PI) of middle cerebral artery(MCA), terminal internal carotid artery(TICA), anterior communicating artery(ACA), and posterior cerebral artery(PCA) from bilateral temporal window before and after polyetheretherketone cranioplasty. PI=(Vs - Vd )/ Vm。

Time frame
6 months

Secondary outcomes

Other outcomes

Sponsors and contacts

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