About this trial
This study aims to systematically evaluate the effects of different anesthesia methods on postoperative chronic cough in lung cancer patients undergoing video-assisted thoracoscopic lung resection (VATS), and to clarify the effectiveness and safety of each anesthesia airway management strategy in reducing the incidence of postoperative chronic cough, shortening the duration of cough, alleviating the severity of symptoms, and improving the postoperative quality of life of patients.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
planned wedge resection, segmentectomy or lobectomy;
more than 18 years old;
American Society of Anesthesiologists (ASA) grade ≤Ⅲ;
body mass index (BMI) ≤24 kg/m2;
Disqualifiers
(1) patients who refuse surgery and/or anesthesia; (2) preoperative pulmonary infection; (3) previous history of ipsilateral surgery or other medical history that may cause extensive pleural adhesions; (4) phrenic nerve palsy on the non-operative side; (5) patients with high risk of preoperative reflux (fasting <6 hours) or gastroesophageal reflux disease; (6) patients with heart, kidney, liver and other organ dysfunction and surgical contraindications; (7) with severe cognitive, psychological and communication disorders.
Trial design
Parallel
Treatments tested in this trial
Patients were randomly grouped
Other interventionAll patients included in the study, were randomized
Treatment groups
Trial outcomes
Primary outcomes
The incidence of postoperative chronic cough, cough duration and cough severity score were recorded
The perioperative follow-up time points were 1 day, 2 days, 3 days, 7 days, 14 days and 1 month after operation. The follow-up time points of postoperative chronic phase were set at 3 months, 6 months and 12 months after operation.
Locations
Sponsors and contacts
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