A Randomized Study on Sagittal Angle Differences in Lower Limbs Between Normal Individuals and Osteoarthritis Patients

ConditionsOATKAEOS
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorChinese PLA General Hospital

About this trial

With China gradually entering an aging society, the proportion of the elderly population is gradually increasing, and the number of patients with knee disease is also increasing year by year. Total knee arthroplasty is one of the effective methods for the treatment of joint disease, which can effectively relieve knee pain, restore function and improve the quality of life. The goal of total knee arthroplasty is to relieve pain, restore function and obtain a long service life. Whether total knee arthroplasty can obtain good alignment is very important for the postoperative recovery of patients. The alignment of lower limb sagittal position is of great significance for evaluating whether the crowd is straightened or not, and can also evaluate and guide the TKA in sagittal position. At present, there are few studies on the sagittal position of the lower limb, and there is no clear definition of whether the lower limb is extended in the sagittal position. At the same time, there is no clear method to evaluate whether the lower limb is extended in the sagittal position in normal people and patients with OA. Therefore, it is urgent to develop a classification standard for the sagittal extension of the lower limb, which can be used in clinical evaluation and TKA operation evaluation. This study will be carried out in the first medical center of the Chinese PLA General Hospital, and a total of about 400 people are expected to be enrolled.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

The age ranged from 18 to 80 years old;

Non OA examinees of lower limb sagittal EOS in the General Hospital of Chinese PLA;

OA patients with sagittal EOS were photographed in the Department of joint surgery, General Hospital of Chinese PLA;

Patients are willing to participate in the study and sign written informed consent.

Disqualifiers

People unable to conduct EOS inspection;

Combined with knee meniscus injury, anterior cruciate ligament injury and other diseases that may affect the sagittal force line of the knee joint

Combined with other diseases that may affect the study

Patients refused to use their imaging data and knee score for this study

Trial population

Non OA patients and OA patients undergoing EOS in our hospital from September 2024 to September 2026.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

400 Participants
are grouped into 2 trial groups
Group A: Health Group
Group B: OA group

Trial outcomes

Primary outcomes

1

Sagittal plane femur lateral, tibia lateral modified mechanical axis angle.

Time frame
From admission to discharge, up to 1 week
2

Angle formed by the line connecting the center of the femoral head, the center of the ankle joint, and the hinge point of the knee joint.

Time frame
From admission to discharge, up to 1 week
3

Sagittal plane femoral anterior arch angle.

Time frame
From admission to discharge, up to 1 week
4

Sagittal posterior slope angle of the tibial plateau.

Time frame
From admission to discharge, up to 1 week

Secondary outcomes

1

Basic demographic profile of the patient

Time frame
From admission to discharge, up to 1 week

Other outcomes

Sponsors and contacts

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