About this trial
Patients at high risk of post-operative pulmonary complications (PPC) will be screened out from gynecological tumor patients undergoing surgical treatment, and randomly assigned into the HFNC group and control group, which uses conventional nasal cannula oxygen therapy. The primary outcome is the incidence of PPC, including postoperative hypoxemia, atelectasis, pneumonia, etc. Secondary outcomes are the improvement of postoperative oxygenation, antibiotic use, length of hospital stay, adverse events related to oxygen therapy, etc.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Assess respiratory risk in surgical patients in Catalonia (ARRSPC) ≥45 points;
BMI≥30;
Moderate to severe asthma;
Moderate to severe chronic obstructive pulmonary disease (COPD);
Disqualifiers
Patients with lung metastasis of malignant tumor or primary lung malignant tumor;
previous lung surgery or radiotherapy;
the surgery involved segmental bowel resection.
Trial design
Parallel
Treatments tested in this trial
heated humidified high flow nasal cannula oxygen therapy, HFNC
DeviceHFNC can accurately provide 21% \~ 100% oxygen concentration through air oxygen mixer. And through the heating and humidification device to provide 37℃, relative humidity of 100% gas, the maximum flow of 70L/min.
Nasal cannula oxygen
DeviceNasal cannula oxygen has become a routine part of postoperative treatment
Treatment groups
Trial outcomes
Primary outcomes
Postoperative pulmonary complication
The primary outcome measures were the incidence of PPC in the treatment group and the control group, including the incidence of postoperative hypoxemia, atelectasis, pneumonia, etc.
Secondary outcomes
Total Hospitalization days
Postoperative Hospitalization Days and ICU Stay Days
Oxygen therapy
The Need for Oxygen Therapy
Antibiotics
The use of antibiotics, including the type, usage, use time, etc.
Postoperative oxygenation
Improvement of Postoperative Oxygenation
Sponsors and contacts
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