A Real World Study of Respiratory Critical Disease.
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMing Zhong
About this trial
Acute Respiratory Distress Syndrome (ARDS) is a form of acute diffuse lung injury caused by various etiologies, which rapidly progresses to acute respiratory failure. It is characterized by a sudden onset and severe clinical course. Globally, ARDS affects approximately 3 million individuals each year, accounting for about 10% of admissions to intensive care units (ICUs). Due to the lack of specific pharmacological therapies, mechanical ventilation remains the mainstay of treatment. Therefore, identifying and analyzing prognostic factors for ARDS patients is of great significance for improving patient outcomes and reducing the incidence of poor prognosis.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients with underlying diseases associated with high risk of ARDS, including but not limited to: sepsis, pneumonia, multiple trauma, pulmonary contusion, inhalation injury, massive blood transfusion, other high-risk conditions, or other factors causing excessive respiratory drive.
Patients meeting the inclusion criteria for a high-risk ARDS population.
Patients (or legal representatives) who have provided a signed and dated informed consent form.
Disqualifiers
Age under 18 years.
HIV infection.
Known immunodeficiency disorders (e.g., leukemia, common variable immunodeficiency, etc.).
History of solid organ or bone marrow transplantation.
Trial population
Patients identified as high risk for ARDS after ICU admission.
Trial design
Design model
Cohort
Time perspective
Retrospective
Treatments tested in this trial
No Intervention: Observational Cohort
Other interventionObsercational study
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Mortality
Clinical observation
Time frame
Day 28 after ARDS diagnosis2
Mortality
Clinical observation
Time frame
Day 60 after ARDS diagnosisSecondary outcomes
1
Chest CT Scan
Chest CT imaging
Time frame
Monitored daily2
Complete Blood Count
Blood sampling and laboratory testing
Time frame
Monitored daily3
Serial Arterial Blood Gas Monitoring
Arterial blood gas collection
Time frame
Monitored daily after enrollment4
Fluid Input and Output Balance
Clinical nursing records
Time frame
Whenever fluid input or output occursSponsors and contacts
Click on the lead sponsor to view all of their trials.
Ming Zhong
Lead sponsor
Shanghai Zhongshan Hospital
Sponsor institution
Source ClinicalTrials.gov