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A Research Study Exploring How Musculoskeletal Function and the Autonomic Nervous System Relate to Visceral Pain in Women With and Without Dysmenorrhea (Painful Periods).

ConditionsDysmenorrheaDysmenorrhea PrimaryVisceral PainMenstrual Pain
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-35
SponsorAzusa Pacific University

About this trial

The purpose of this clinical trial is to determine if women with dysmenorrhea demonstrate an increased musculoskeletal and autonomic nervous system response to a painful visceral stimulus compared to controls. A secondary aim is to determine if interoceptive awareness moderates this relationship. The designed methodology aims to elucidate the intricate connections between the interoceptive and musculoskeletal systems in pain perception among female participants, providing valuable insights into the underlying mechanisms of interoceptive pain and functional musculoskeletal changes.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial design

Design model

Single group

Treatments tested in this trial

  • Visceral Pain Stimulus

    Diagnostic test

    Participants will receive a visceral pain stimulus while being monitored for heart rate variability (HRV), and will have hip mobility and dorsiflexor strength assessed before and after.

Treatment groups

60 Participants
are divided into 1 treatment group
Group A: Visceral Pain StimulusExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Change in hip range of motion

The change in hip range of motion from baseline to after a visceral pain stimulus is a primary outcome measure of this study. This measurement will be compared between groups to determine if those with dysmenorrhea react to a painful stimulus differently compared to those without dysmenorrhea.

Time frame
Change from baseline to immediately after the pain stimulus is given.
2

Change in dorsiflexor strength

The change in strength of ankle dorsiflexors on the contralateral side of the hip being measured will also be assessed. This will be measured before and after the visceral pain stimulus to determine if there is a change. This measurement will be compared between groups to determine if those with dysmenorrhea react to a painful stimulus differently compared to those without dysmenorrhea.

Time frame
From baseline to immediately after the pain stimulus.
3

Heart Rate Variability

Heart rate variability will be measured throughout, and several time frames will be marked, including a 5-minute baseline within a 15-minute session, at the time of insertion of the probe, and at the pain stimulus, to determine if those with dysmenorrhea react to a painful stimulus differently compared to those without dysmenorrhea.

Time frame
From baseline to the end of the lab testing session, approximately 60 minutes.

Secondary outcomes

1

Interoceptive awareness

Participants will also be given the multidimensional analysis of interoceptive awareness, 2nd edition (MAIA-2), to assess their interoceptive awareness.

Time frame
During the testing day, following physical pain stimulus.

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Azusa Pacific University

Lead sponsor

Source ClinicalTrials.gov
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