A Resilience-Based Approach to Improve Long-term Quality of Life in Post-treatment Lymphoma Survivorship

ConditionLymphoma
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMassachusetts General Hospital

About this trial

The goal of this trial is to learn if a resilience intervention can lead to improvements in lymphoma survivors' quality of life.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

English or Spanish speaking adults (18+ at time of enrollment)

Within 1-5 years of completing active treatment for lymphoma (includes surgery, chemotherapy, immunotherapy, radiation therapy, or other); individuals may be on maintenance treatment.

Disqualifiers

Active psychiatric, medical concern or cognitive comorbidity as determined by the site PI or treating clinician

Trial design

Design model

Parallel

Treatments tested in this trial

  • Health Education Program

    Other intervention

    8 weekly sessions that include education on the co-occurrence of mental and physical problems, goal setting for health behavior change, and self-monitoring. Each session includes basic didactic information, interactive application of the information, and open discussion of didactic material.

  • SMART3RP-Lymphoma

    Other intervention

    The SMART3RP-lymphoma is a group program that, through a variety of mind-body approaches, such as imagery, relaxation, and yoga, seeks to buffer stress and promote psychological resiliency and physical well-being.

Treatment groups

254 Participants
are divided into 2 treatment groups
Group A: Health Education ProgramActive comparator 1 intervention
Group B: SMART3RP-LymphomaExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Quality of Life (QoL): Change in PROMIS-29

To examine the effects of the SMART3RP-Lymphoma vs. a Health Education Program (HEP) in improving quality of life in early posttreatment lymphoma survivors. Quality of life will be measured using the PROMIS-29 which assesses physical, functional, emotional, and social quality of life. Each survey item is measured on a 1-5 scale. The unit of measurement is a score on a scale.

Time frame
From enrollment to 6 month follow up

Secondary outcomes

1

Resilience: Change in Scores on the Current Experiences Scale (CES)

To compare the effects of the SMART3RP-Lymphoma vs. a Health Education Program (HEP) on resilience in posttreatment lymphoma survivors. Resilience will be measured by the Current Experiences Scale (CES). The CES is a 23-item measure that assesses the following domains of resilience on 0-5 scale: appreciation for life, adaptive perspectives, personal strength, spiritual connectedness, relating to others, and health behaviors. The unit of measurement is a score on a scale.

Time frame
Enrollment to 3 month follow up

Other outcomes

1

Correlation between scores on measures of Resilience (CES) and Quality of Life (PROMIS-29)

The investigators will determine how resilience at 3 months correlates to quality-of-life improvements at 6 and 12 months. Resilience will be measured by the Current Experiences Scale (CES), which is a 23-item measure. The CES assesses 6 domains of resilience including appreciation for life, adaptive perspectives, personal strength, spiritual connectedness, relating to others, and health behaviors). Quality of life will be measured by the PROMIS-29 which is a 29-item measure. It assesses physical, functional, emotional, and social quality of life domains. The unit of measurement for both assessments are scores on a scale.

Time frame
3, 6 and 12 months

Sponsors and contacts

Click on the lead sponsor to view all of their trials.