This study used a retrospective cohort study based on Multi-time longitudinal monitoring data were used to analyze the correlation mechanism between the dynamic evolution characteristics of nutrition-related biochemical indicators and individualized nutritional intervention in patients with mechanical ventilation. The inflammation-nutrition interaction model was constructed to correct the interference effect of inflammatory microenvironment on nutritional status assessment, so as to provide a basis for further achieving precision nutritional support.
age ≥18 years old;
ICU admission ≥72 hours with invasive mechanical ventilation ≥24 hours;
start nutrition therapy within 72 hours after ICU admission and receive enteral or parenteral nutrition support for ≥3 days;
Relatively complete nutritional intervention records and nutrition-related biomarkers test results on the 1st, 3rd, and 7th (±1) days of ICU admission;
women of childbearing age who have a positive pregnancy test, are pregnant or lactating;
chronic diseases with serious organ function damage or serious complications;
Kidney: chronic kidney disease stage 4 or 5;
Liver: previous history of liver failure, hepatic encephalopathy, or hepatic coma, gastrointestinal bleeding due to portal hypertension or Child-Pugh score ≥10 in recent years;
Patients admitted to the ICU
Cohort
Retrospective
Not listed
ICU mortality
Hospital mortality
Length of mechanical ventilation
Length of ICU stay
Length of hospital Stay
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options:
